Vasoconstrictor nose drops rhinonorm. Rinonorm spray instructions for use
Instructions for use
Rinonorm-teva 0.1% 20ml spray nasal doses instructions for use
Dosage form
clear colorless solution
Compound
Xylometazoline hydrochloride 1 mg
Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water for injection.
Pharmacodynamics
Alpha-agonist for local use in ENT practice.
At topical application xylometazoline causes constriction of arterioles, leads to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretions. A distinct local effect of the drug is detected after a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of the patency of the nasal passages, sinus openings and Eustachian tubes. Restoration of air permeability of the nasopharynx improves the patient's well-being and reduces the risk possible complications caused by congestion of the mucous secretion.
Pharmacokinetics
When applied topically, xylometazoline is practically not absorbed, so plasma concentrations are very low (not analytically determined).
Side effects
Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the nasal mucosa, oral cavity and larynx.
From the side of the central nervous system: rarely - headache; rarely (< 1/10 000) - бессонница, повышенная возбудимость.
From the side of cardio-vascular system: rarely (< 1/10 000) - аритмия, увеличение АД.
Other: rarely - nausea; rarely (< 1/10 000) - кожные реакции.
Selling Features
Released without a prescription
Special storage conditions
after opening the vial - 1 year.
Special conditions
Influence on the ability to drive vehicles and control mechanisms
There was no effect on the ability to drive vehicles and control machines and mechanisms.
Indications
Rinonorm is used as a symptomatic therapy for the following diseases and states:
Acute viral or bacterial rhinitis;
Acute allergic rhinitis;
Acute sinusitis or exacerbation of chronic sinusitis;
Spicy otitis media(to reduce swelling of the mucous membrane of the Eustachian tube);
Preparing the patient for diagnostic procedures in the nasal passages.
Contraindications
Atrophic (dry) rhinitis;
Angle-closure glaucoma;
Condition after hypophysectomy;
Simultaneous use of MAO inhibitors and tricyclic antidepressants;
Children under 10 years of age (for adult spray);
Hypersensitivity to xylometazoline or other components of the drug.
The drug should be used with caution in arterial hypertension, serious illnesses heart, hyperthyroidism, diabetes mellitus and patients taking bromocriptine.
Use during pregnancy and lactation
The drug should not be taken during pregnancy.
The drug should be used with caution during breastfeeding.
drug interaction
Simultaneous use of tri- or tetracyclic antidepressants may increase the systemic exposure to xylometazoline.
While taking the drug with MAO inhibitors, there is a risk of increasing blood pressure.
Mode of application
Dosage
Adults and children over 10 years of age are prescribed Rinonorm nasal spray 0.1%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times / day.As much as possible, the drug can be used no more than 7 times / day. The interval between the administration of the drug should not be less than 6 hours.
The amount of fluid entering the patient's nasal passage (1 dose) is 0.14 ml of solution.
In order to avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
Before using the drug, the nasal passages should be freed from the secret. During the administration of the drug, a light breath should be taken through the nose.
Overdose
Symptoms: in rare cases overdoses that occur mainly in children, arrhythmia, increased blood pressure, and in some cases loss of consciousness can be observed.Treatment: shown symptomatic therapy under control. In severe cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally take a moderate or large amount of the drug inside, you should take Activated carbon and a laxative (such as sodium sulfate), do a gastric lavage.
Rinonorm: instructions for use and reviews
Rinonorm is a vasoconstrictor that reduces hyperemia and swelling of the mucous membranes of the nasopharynx. Used in ENT practice.
Release form and composition
Dosage form - dosed nasal spray 0.05% (for children) and 0.1%: a clear colorless solution (15 ml each in dark glass bottles equipped with a dosing device and a nasal nozzle, in a pack of cardboard 1 bottle).
Active substance: xylometazoline hydrochloride - 0.5 or 1 mg per 1 ml.
Auxiliary components: citric acid monohydrate, glycerol 85%, sodium citrate dihydrate, water for injection.
Pharmacological properties
Rinonorm is characterized by a pronounced anticongestive effect on the human body.
Pharmacodynamics
The active component of the drug - xylometazoline - is an adrenomimetic that promotes narrowing of arterioles. This favorably affects the condition of the mucous membranes of the nasopharynx, reducing swelling and eliminating hyperemia. Rinonorm improves the patency of the Eustachian tubes, sinus openings and nasal passages, and also reduces the risk of complications associated with prolonged secretion stagnation.
Pharmacokinetics
With topical application of Rinonorm, the amount of secretion in the nasopharynx decreases within a few seconds after the intake of xylometazoline in the body. The effect of the drug persists for another 3-4 hours.
Indications for use
Symptomatic treatment:
- Acute sinusitis and exacerbation of chronic sinusitis;
- Acute rhinitis of bacterial and viral origin;
- Acute allergic rhinitis;
- Acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube).
According to the instructions, Rinonorm can also be used during the preparation of the patient for diagnostic procedures in the nasal passages.
Contraindications
- Children's age up to 2 years - for 0.05% spray, up to 10 years - for 0.1% spray;
- Atrophic (dry) rhinitis;
- Conditions after hypophysectomy;
- Angle-closure glaucoma;
- Concomitant use of tricyclic antidepressants or monoamine oxidase inhibitors;
- Pregnancy;
- Hypersensitivity to any component of Rinonorm.
Carefully:
- lactation period;
- Diabetes;
- Hyperthyroidism;
- severe heart disease;
- Arterial hypertension;
- Simultaneous use of bromocriptine.
Instructions for use Rinonorm: method and dosage
Nasal spray Rinonorm is applied intranasally.
Adults and children over 10 years of age are prescribed 0.1% spray - 1 dose in each nasal passage up to 3 times / day.
Children 2-10 years old are prescribed 0.05% spray - 1 dose in each nasal passage up to 3 times / day.
1 dose corresponds to 1 pressure on the piston and is 0.14 ml of solution.
The interval between injections should be at least 6 hours. The maximum frequency of use of the drug is 4 times a day.
Duration of continuous treatment - no more than 7 days.
Before instillation of the spray, the nasal passages should be cleared of secretions.
During the administration of the drug, you need to take a light breath through the nose.
Side effects
- Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the oral mucosa, nose and / or larynx;
- From the side of the cardiovascular system: extremely rarely (less than 1 case out of 10,000) - heart rhythm disturbances, increased blood pressure;
- From the side of the central nervous system: rarely - headache; extremely rarely - irritability, insomnia;
- Other: rarely - nausea; extremely rarely - reactions on the skin.
Overdose
Cases of overdose of the drug have been registered mainly in children and are expressed in arrhythmias, increased blood pressure, and in some cases - fainting.
As a treatment, symptomatic therapy under the supervision of a specialist is recommended. In severe cases, non-selective alpha-blockers are used to lower blood pressure, and also resort to intubation and mechanical ventilation. Vasoconstrictor agents are prohibited. In case of accidental intake of Rinonorm in moderate or large amounts, it is necessary to take a laxative (for example, sodium sulfate) and activated charcoal, and gastric lavage.
Rinonorm is a local vasoconstrictor. It is prescribed to eliminate nasal congestion due to edema in infectious, inflammatory and allergic diseases, which are accompanied by a profuse runny nose. The article sets out detailed instructions on the use of Rinonorm for adults and children.
The chemical composition and medicinal properties of the solution
The main active ingredient of the drug is xylometazoline. This is an alpha-adrenergic stimulant - it affects the receptors that cause various functional changes in the body. The chemical is an anticongestant, has a vasoconstrictive, anti-edematous effect. When it enters the mucous membrane, it causes vasoconstriction - a narrowing of the lumen of small-caliber vessels.
Auxiliary components in the preparation:
- citric acid - preservative, acidity regulator;
- sodium dihydrate - complexing agent;
- glycerol - a stabilizer for the viscosity of the solution;
- water for injections.
Rinonorm drops are intended for intranasal use in otolaryngology. The medicine narrows the small arteries of the capillary network of the nasal mucosa and paranasal sinuses. This eliminates puffiness, restores the patency of the nasal passages, and resumes breathing.
The drug reduces the severity of inflammation, hyperemia of the epithelium. The solution stabilizes the secretory glands. After applying the product, the production of pathological exudate decreases, profuse rhinorrhea (runny nose) disappears.
With allergic inflammation of the mucosa after irrigation with a solution, symptoms such as itching, burning, irritation disappear.
Rinonorm restores the patency of the paranasal sinuses, improves ventilation in them. This prevents the development of stagnant processes associated with the accumulation of mucus, the accession bacterial infection. The use of the solution reduces the risk of complications, especially in children:
- eustachitis - inflammation of the Eustachian tube;
- otitis media;
- sinusitis;
- tracheitis, bronchitis, pneumonia.
After nasal administration, the drug begins to act after 5-7 minutes. The therapeutic effect lasts for 6-10 hours, depending on the characteristics of the organism.
The drug is absorbed into the systemic circulation in minimal amounts, with laboratory research blood using analytical methods, the substance is not determined.
Indications for prescribing a solution
Rinonorm nose drops are prescribed as part of complex therapy for infectious and inflammatory processes of the nasal mucosa and sinuses:
- acute rhinitis of various etiologies (viral, bacterial, fungal);
- chronic inflammation of the epithelium of the nose during an exacerbation;
- sinusitis - sinusitis, frontal sinusitis, ethmoiditis;
- inflammation of the nasopharyngeal organs, which are accompanied by severe runny nose;
- allergic perennial rhinitis in the acute phase;
- pollinosis - a seasonal allergic disease associated with inflammation of the nasal mucosa and conjunctiva of the eyes;
- eustachitis - inflammation of the duct connecting the nasal cavity and pharynx.
The instructions for use contain information that the solution is applied to the nasal mucosa before a diagnostic study using an endoscope.
A vasoconstrictor is used for severe edema before the introduction of antiseptic and disinfectants.
Rhinonorm for children is indicated for otitis media. Drops drip into the nose to restore ventilation and prevent the spread of infection.
Forms of drug release and treatment regimens
The drug is available as a solution for topical use.. It's colorless clear liquid, does not contain impurities, sediment and other particles. Solution without a specific smell.
The country of origin is Germany. The average price of 1 bottle of 15 ml is 70 rubles.
Before irrigating the epithelium, the passages must be thoroughly cleaned of mucus, pus and other pathological exudate using saline solutions for sanitation - Salin, Humer, Aqua Maris.
Rinonorm for children is a 0.05% solution. Spray is prescribed for babies over 2 years old. Treatment regimen: 1 injection in each nostril up to 3 times a day, at regular intervals (6-8 hours).
Adults and children after 12 years of age are prescribed a nasal spray concentration of 0.1%. In each nasal passage, 1-2 doses are injected 3 times a day.
The maximum therapeutic course should not exceed a week.
Side effects during treatment
Most often, patients experience side effects in the form of local allergic reactions, especially in children:
- increased redness of the mucosa, swelling;
- itching, burning, sneezing;
- skin rashes, urticaria;
- irritation of the nasopharynx, larynx.
Less commonly, reactive hyperemia develops - a sharp filling of blood vessels with a volume of blood that exceeds the norm by 5 times. This occurs after prolonged vasoconstriction (narrowing) of the capillary lumen.
When the solution flows into the gastrointestinal tract along the back wall of the nasopharynx, nausea occurs. Heartburn, discomfort in the epigastric region.
The drug may worsen the general condition of the patient. This is manifested by such symptoms:
- headache, dizziness;
- failures of heart rhythms;
- slight increase in blood pressure;
- insomnia at night, sleepiness during the day;
- increased nervous irritability and excitability.
Overdose
The facts of an overdose, subject to the prescribed scheme, are excluded. With abuse and frequent use, more than 5 times a day, in patients with cardiovascular pathology, pressure surges, arrhythmia, and in severe cases, loss of consciousness can be recorded.
When used for more than 7 days, drug rhinitis is manifested - a condition in which addiction to the solution occurs. In this case, the signs of rhinitis return with increased intensity.
It is strictly forbidden to exceed the prescribed dosage in children under 5 years of age. The nasal mucosa of babies is different in that any medicine that gets on it is immediately absorbed into the bloodstream. Vasoconstrictor drugs in the blood increase blood pressure and heart rate. This will significantly worsen the general condition of a small patient, provoke the appearance of seizures.
Contraindications for the appointment of a solution
Contraindications to the use of a nasal spray are such conditions and internal diseases:
- atrophic rhinitis - degenerative changes in the nasal mucosa, followed by thinning and loss of function;
- angle-closure glaucoma - overlap of the iris of the anterior chamber of the eye;
- children under 2 years old;
- individual intolerance to the chemical components of the drug.
Pregnant women are prescribed Rinonorm with caution. The solution is not absorbed into the systemic circulation, but there is an assumption that it disrupts the vascular tone of the placenta and the blood supply to the embryo. During lactation, the drug is safe.
Vasoconstrictor drops are contraindicated along with antidepressants.
Rinonorm for adults and children is a drug emergency care with a profuse runny nose, severe swelling of the mucosa, lack of nasal breathing. Its instant action allows you to quickly alleviate and stabilize the general condition of the patient. If the prescribed dosages are observed, the solution is safe for health. At a cost, the medicine is accessible to all social strata of the population.
Rinonorm - nasal dosed spray, given to children and adults. It has a vasoconstrictive effect, prescribed by an otolaryngologist.
It can be used independently, subject to the indications and following the instructions, it is released without a doctor's prescription. In everyday life, it is quite popular and is used by people primarily to combat the symptoms of colds, allergies, sinusitis and other diseases that affect patency. respiratory tract cause runny nose and nasal congestion.
Highly valued for ease of use and compactness.
Instructions for use
In what cases is it used:
- is prescribed to relieve inflammation of the nasal cavity caused by allergies, the action of bacteria or viruses;
- relieves the symptoms of sinusitis in the acute course of the disease or exacerbation of the chronic form;
- reduces swelling of the Eustachian tube mucosa in acute form of otitis media;
- can be useful when it is necessary to prepare the patient's nasal passages for diagnosis. Reduces hyperemia, relieves swelling, improves well-being.
Mode of application
It is used as a nasal spray, injected into the nose by pressing the plunger, and is available in two forms with different dosages:
- Children from two years of age are prescribed a spray containing 0.05% of the active substance. Daily introduction into each nostril is allowed no more than three times.
- Children from ten years of age and adults are prescribed a spray containing 0.1% of the active substance. Similarly, no more than three injections into each nostril daily are allowed.
Both children and adults need to use the drug no more than once every six hours. When you press the sprayer, 0.14 milliliters are released.
The maximum allowed to use the drug without interruption no longer than a week. It is preliminary recommended to free the nose from mucus and secretions, and after the administration of the drug, you need to slightly draw air through the nose.
Forms of release and composition of the drug
Produced in dark glass bottles with a capacity of 10 or 15 milliliters, packed in cardboard boxes. A dosing piston is put on the vial, which must be pressed to inject the drug into the nose.
The piston is protected from accidental pressing by a special cap. The dosage is of two types, 0.05% and 0.1%, indicated on the package.
The composition includes:
Side effects
During use, the following side effects are possible:
- burning and dryness in the nose, less often - irritation of the mucous membranes of the larynx, nose and mouth;
- rarely - headache, nausea;
- less than 0.01% of cases - irritability and insomnia, arrhythmia, increased blood pressure, skin irritation.
- should not be used for dry rhinitis, angle-closure glaucoma.
- not prescribed after hypophysectomy.
- used separately with tricyclic antidepressants and monoamine oxidase inhibitors.
- it is forbidden to give rhinonorm to children under two years of age.
- it is forbidden to give a spray with a dosage of 0.1% to children under ten years of age.
- contraindicated in case of hypersensitivity and intolerance to the components.
It is recommended to use cautiously and after consultation with a specialist in patients with severe heart disease, diabetes mellitus, arterial hypertension and hyperthyroidism.
During pregnancy
Terms and conditions of storage:
The optimal temperature range for storage is from +15 to +25 degrees Celsius.
The drug "Rinonorm", according to the instructions for use, copes well with infectious and inflammatory processes in the nasal cavity. If the recommended dosage and duration of treatment are observed, the drug relieves swelling, reduces nasal discharge and prevents the spread of infection to neighboring departments. Be sure to take into account contraindications and side effects.
The drug "Rinonorm" is produced in the form of a clear, odorless solution for administration into the nasal cavity. The carton box contains a dark-colored bottle of 10 or 15 ml and detailed description on the use of the spray. Drops are easy to dose, as there is a convenient nozzle for spraying.
The active substance of the nasal preparation is xylometazoline hydrochloride. Spray "Rinonorm" has two varieties that differ in the dosage of the active substance: 5 mg or 10 mg. There are also auxiliary components that enhance the therapeutic effect.
pharmachologic effect
When administered locally, the drug has the following effects:
- constricts blood vessels, as a result, swelling of the mucous surface of the nose and paranasal sinuses is eliminated;
- the area of inflammation decreases;
- the likelihood of complications is reduced, since fluid stagnation in the sinuses is excluded.
The action of the drug begins almost immediately after administration. The amount of mucus secreted in the nasopharynx decreases, nasal breathing is facilitated, pain in the head disappears. The patency of the nasal cavities and sinuses, as well as the Eustachian tube, is restored. Action is enough for 5-6 hours.
Indications for use
Spray "Rinonorm" is prescribed for diseases, the main symptom of which is a runny nose and nasal congestion:
- Drops help get rid of a runny nose caused by viruses, bacteria, allergens.
- Treats otitis media.
- Discharged for chronic or acute inflammation occurring in the paranasal sinuses.
The drug is instilled before various diagnostic procedures performed in the area of the nasal passages.
Contraindications and side effects
The cases when the spray "Rinonorm" is contraindicated include:
- spray dosage of 0.05% can not be used under the age of two years, a dosage of 0.1% is contraindicated in children under 11 years of age;
- atrophic rhinitis or runny nose, accompanied by dryness in the nasal cavity;
- severe diseases of the organs of vision;
- intolerance to the components that make up the solution.
With caution, the drug is prescribed to patients who have hypertension, severe heart pathologies, diabetes or hyperthyroidism.
Adverse reactions most often occur with improper dosing or prolonged use of the drug. Negative responses include:
- dryness and burning in the nasal passages;
- nausea;
- pain in the head;
- insomnia;
- increased blood pressure;
- itching and rash on the skin;
- violation of the heart rhythm.
If one of these symptoms appears, treatment is stopped, informing the attending physician about the condition.
Instructions for use "Rinonorm"
- before injecting the drug, the nasal cavity is cleaned of accumulated mucus;
- it is useful to wash the nose with saline;
- only after these procedures, the nozzle of the bottle is inserted alternately into each nostril, and the sprayer is pressed;
- at the time of spraying the solution into the nose, it is recommended to take a shallow breath.
Instructions for use assumes the following dosing of the drug:
- for children older than two years and up to 10 years, a 0.05% spray is chosen, which is administered one injection into each nostril three times a day;
- for patients older than 10 years and adults, a 0.1% spray is chosen, which is also injected three times.
For one session, you need to do one injection in each nostril. You can not use the drug more than 6 times a day. The interval between the introduction of the solution should be more than 5 hours. The duration of treatment should not exceed a week.
Overdose
An overdose develops extremely rarely. If the recommended dosage and duration of treatment are not observed, the following symptoms appear:
- heartbeat quickens;
- blood pressure rises;
- joins nausea and pain in the head;
- worried about dryness and tingling in the nose.
In case of exceeding the doses, it is necessary to wash the nose, stomach and take an antihistamine and laxative.
Use during pregnancy and lactation
Pregnancy is often accompanied by nasal congestion, which is associated with hormonal changes in the body. The permeability and work of the vessels changes, edema occurs. The condition is dangerous for the development of fetal hypoxia. In addition, immunity decreases, and a woman becomes more easily infected with viruses and bacteria.
The drug "Rinonorm" can not be used in the first trimester of pregnancy, as the active ingredients increase the risk of miscarriage and adversely affect the development of the fetus. It is better to opt for safer drugs, for example, Aquamaris, Marimer, Salin.
In the second and third trimester, the drug is prescribed in extreme cases, when the condition threatens the development of the fetus. As a rule, a children's version of the drug is prescribed. It is best to use the spray once, before going to bed.
The drug is released along with breast milk, so for the period of treatment it is better to replace it with mixtures.
Interaction with other drugs
Nasal solution "Rinonorm", if necessary, can be used simultaneously with antihistamines and antibiotics.
You can not combine the drug with tetracyclic antidepressants.
Terms of sale in pharmacies
The drug is supplied to all pharmacies, dispensed without a special prescription. The average price for the drug is 100 rubles.
Terms and conditions of storage
The shelf life of the spray "Rinonorm" is three years. The solution in the opened vial retains its medicinal properties over the course of one year.
The medicine should be stored in a dark place that is not accessible to children, at an air temperature of no more than +25 degrees.
Analogues
Analogues of the spray "Rinonorm" are considered: "Galazolin", "Otrivin", "Xilen", "For Nos", "Brizolin", "Tizin xylo", "Farmazolin".
