Hexicon d is it possible for adults. Hexicon ® D (vaginal suppositories)

Instructions for use of candles Hexicon describes in detail their use for treatment various diseases urinary system, can also be prescribed in the course of therapy for infections of the reproductive system in women of any age, including children.

The product is an antiseptic and disinfectant for external use. Its bactericidal qualities cause a quick effect in the treatment of disorders of bacterial origin.

Candles Hexicon are available in the form of suppositories, that is, they are solid at room temperature and melt at body temperature. They are cylindrical in shape with a slightly pointed end. White colour. The surface is smooth.

Candles are sold in a carton box containing two contour cellular plates of 5 suppositories each. Instructions are also attached to the preparation.

Compound

The healing substance of Hexicon suppositories is chlorhexidine bi-gluconate in the amount of 16 mg in each individual dose (candle). Additional working components: polyethylene oxide (1500) and (400). These substances form the mass of the suppository (3.1 g) and ensure its uniform melting inside the body.

Efficiency

Chlorhexidine bi-gluconate is an antiseptic that has a bactericidal effect, destroying bacteria. Its mechanism of action is that it destroys cell membranes by osmotic dissociation, that is, it contributes to their breakdown into ions.

The drug is effective for combating many infectious bacteria, while it is useless for the treatment of viruses, acid-fast microorganisms, fungi. In the vagina, the Hexicon suppository melts, enveloping the mucous membrane, while not being absorbed into the bloodstream.

The drug Hexicon is used against such bacterial infections:


Candles work well even in the presence of pus and blood. Suppositories can also be used during menstruation.

The drug Hexicon, in addition to antibacterial, has a spermicidal effect. Therefore, it can be used before the onset of sexual intercourse - not only for the prevention of infection with a sexual infection, but also as a contraceptive. However, it should be borne in mind that the instructions for use do not provide for the constant use of suppositories as a counter to conception.

Indications for use

Hexicon suppositories (instructions for the use of suppositories describe their use in therapy and prophylactic treatment against diseases that occur by infection through sexual contact) can be used under different circumstances.

For instance:


For fungal diseases (candidiasis), Hexicon suppositories are not used, due to inefficiency.

The effectiveness of the use of Hexicon suppositories for the prevention and in the complex therapy of many well-known bacterial infections, such as gonorrhea, gardanerella, chlamydia, syphilis, trichomoniasis, genital herpes, mycoplasmosis, ureaplasmosis, has been repeatedly proven in practice.

But suppositories are also used as a disinfectant to prevent possible inflammatory complications before research, childbirth, cleansing, and surgical operations.

Contraindications for use

Candles should not be used in cases of:

  • individual intolerance;
  • pronounced sensitivity of mucous membranes to substances contained in suppositories;
  • for the treatment of children under 12 years of age (there is a special children's drug Hexicon D);
  • the presence of dermatitis.

Suppositories are used only for the treatment of female diseases. Before you start taking suppositories, you should test the drug for individual intolerance.

Dosage and administration

Suppositories are used by inserting them into the vagina.

They are used:

  • to prevent infection with sexual infections: before sexual intercourse or immediately after;
  • for the treatment of various pathologies of the vagina with pathogenic bacteria: regular use is recommended for a ten-day course, with a possible extension;
  • for disinfection before the need for surgical intervention: appoint one candle for a period of two to three days.

The introduction of the suppository requires the adoption of a horizontal position, preferably with a raised pelvis (you can put a pillow under it), followed by rest for one to two hours.

Hexicon suppositories are extremely convenient to use, as they do not require douching before use. However, increased vaginal discharge during the treatment period necessitates more intensive use of daily hygiene products (pads, tampons).

To increase the therapeutic effect of the course of taking Hexicon suppositories, it is recommended to avoid sexual contact, since their continuation during treatment can contribute to re-infection and reduce the effectiveness of the process.

Use during pregnancy and lactation

Hexicon suppositories (instructions for use allow the use of the drug during pregnancy) are absolutely safe and do not affect either the mother's body or the fetus. The need for use may be caused by a weakening of the immune system, changes in the vaginal microflora, due to the restructuring of the female body.

Such processes disrupt the immune system and allow pathogens to infect the organs of the intimate sphere. If this is not stopped in time, then the excess accumulation of harmful biological forms can adversely affect the fetus, infecting it.

The suppository dissolves inside the vagina, without getting into the gastrointestinal tract, or into the blood, or into the placenta. To be sure of the complete safety of the drug Hexicon, a woman can consult a specialist to identify allergic effects on the main active ingredients.

The overall effect of candles is to form normal microflora into the vagina, which is important for the course of pregnancy without complications. Gesikon is also used after childbirth - it counteracts purulent pathologies that can occur on fresh sutures and in unrecovered birth canals.

During the period of breastfeeding, the possible risks of genital infections increase, since the immune system does not immediately recover after childbirth. After all, the main resources of the body are directed to lactation.

Since suppositories are not absorbed into the blood, their use is allowed during breastfeeding. An exception may be allergic manifestations (itching, burning, rashes).

Dosages:

  • for preventive purposes, Hexicon can be prescribed before childbirth for admission within 5 days, 1 suppository;
  • for the purposes of therapy, the drug is administered twice a day, one suppository, freeing it from the plastic shell.

Method of application during pregnancy: insert the suppository into the vagina to the depth of one finger, preferably lying down. For convenience, you can bend your knees. During the period of application of the suppository, hygiene is carried out without the use of soap (instead of it, potassium permanganate can be used in a weak solution).

For kids

For the treatment of girls from 6 months before the onset of menstruation, Hexicon D suppositories are used. This drug has a halved dosage of the active substance. For children, candles are produced in the form of single doses weighing 8 mg of white color, with a consistency resembling paraffin. Candles are odorless. The box contains two plates with cells, 5 suppositories each.

As a positive factor in the use of the drug can be called the absence of violations of the vaginal microflora. The remnants of suppositories are excreted through the intestines.

For use, the Hexicon candle is removed from the cell and inserted into the vagina, after which it is recommended to lie down with a slightly raised pelvis. Usually two suppositories are prescribed per day. For a general course of administration, you will need 20 suppositories or two packs of the drug.

Can it be used during menstruation?

Hexicon suppositories (instructions for use allow the use of the drug during menstruation, if they began during the course of treatment) create an acidic environment. Since the blood has an alkaline composition, it can reduce the effectiveness of the suppository by neutralizing the environment created by it.

Side effects

Symptoms indicating a tendency to side effects from taking Hexicon suppositories are individual.

They are usually expressed like this:

  • the presence of itching;
  • allergic reactions on the skin;
  • feeling of stickiness in the palms;
  • increased sensitivity to light, namely to ultraviolet rays (redness of the skin when exposed to sunlight).

Allergy can be expressed in the urge to urinate, itching, burning, swelling of the mucosa, bleeding of the labia and vagina.

Candles are used exclusively by inserting a suppository into the vagina, that is, they are not intended to treat infections on other mucous membranes. However, the components that make up Hexicon (chlorhexidine bi-gluconate) can be used to treat gingivitis.

In this case, the side effects may be unexpected, such as tooth staining. These symptoms do not apply to Hexicon suppositories, since suppositories are not intended for the treatment of dental diseases.

special instructions

Directions:


Overdose

There were no established cases of overdose with Hexicon suppositories (the medicine does not harm health and does not disrupt the functioning of the body, being well tolerated by them). It is worth paying special attention to individual manifestations of the effect of intolerance to some of the constituent components of candles.

This applies to reactive reactions (itching, burning, rashes at the site of action of the suppositories). After all, if such reactions exist, they will disrupt the productive course of treatment. As a rule, the manifestation of undesirable reactions to the drug, including allergic ones, with rashes and itching, stops simultaneously with the completion of the intake.

Therefore, unexpected side effects may cause a desire to stop treatment, which should not be done immediately. As a rule, sometimes you need to be a little patient. Usually the first reaction to the drug in the form of a burning sensation is temporary, not manifesting itself in the future.

If the pain effects are unbearable and cause a persistent urge to urinate, then the remnants of the suppositories should be washed off with soap and water and after a while try to repeat the introduction of the drug into the vagina again. As a rule, repeated use does not cause irritation.

How to deal with unpleasant side effects:

  1. Washing the surface with soapy water, intimate soap, shower gel.
  2. The use of douching with Miramistin solution (the solution is injected with a syringe for 15 minutes). Instead of Miramistin, you can use an infusion of chamomile inflorescences. It is prepared by brewing two tablespoons of the collection in 300 ml of water and then heating it over low heat for up to 15 minutes.
  3. Sitz baths (you can use chamomile, celandine. Calendula). Dry fees for this are poured with boiling water and filtered.
  4. To neutralize the side effects of taking Hexicon, it is recommended to use Zalain soothing suppositories, which are inserted into the vagina.

drug interaction

The action of Hexicon is neutralized with an ordinary soapy solution. This should be taken into account and not used for douching soap and formulations based on it. Hexicon is also not used simultaneously with iodine-based drugs. It is acceptable to use suppositories together with benzalkonium (chloride), cetrimonium (bromide).


Candle Hexicon. Instructions for use states that it is impossible to use soap and compositions based on it for douching in parallel.

There are also some substances that increase the effectiveness of the effect of chlorhexidine on the mucous membrane, for example, ethanol. Therefore, taking ethanol-based drugs during the period of treatment with suppositories will be useful.

Terms and conditions of storage

After purchase, suppositories must be kept at a temperature that excludes their melting, which begins at 23 degrees Celsius - that is, the ideal conditions for the drug are a refrigerator. Shelf life of Hexicon candles from the date of issue is no more than three years.

Where to buy the drug

Hexicon suppositories (instructions for the use of this medication describe the dosage and forms of release of suppositories) are over-the-counter drugs, therefore they are available for purchase at any pharmacy without a special form from a doctor.

Usually Hexicon candles are packed in a cardboard box containing two plastic honeycomb shells of 5 pcs. suppositories in each (16 mg - the weight of each individual dose). Such packaging is sold at a price of 200 rubles. Children's candles Hexicon D are also sold in over-the-counter departments of pharmacies. One box contains 10 doses of 8 mg each.

Doses are packed in a honeycomb shell - 5 pcs. in each. Hexicon D can be bought at a price of 250 rubles. for a box.

Analogues

The main substitutes for Hexicon are drugs that are used to treat a similar range of diseases and have a comparable effect on the body. As a rule, in the case of Hexicon, only drugs that contain a solution of chlorhexidine can act as complete analogues.

There are few of them:

  1. Viferon- a popular analogue of Hexicon in the form of candles for the treatment of certain diseases. The drug is prescribed in the treatment of pathologies in women of infectious origin: vaginosis, candidal and trichomonas vaginitis. Its main purpose is the sanitation of the vagina before research and surgical operations. The drug has a rigid therapeutic focus and to start its use, it is necessary to consult with specialists.
  2. Amident- it can be found in pharmacies in the form of a liquid solution. As a rule, the drug is prescribed in the preparatory and therapeutic treatment sexual infections (both sexually transmitted and arising due to a decrease in immunity). Amident's solutions are recommended to be used immediately after sexual contact by douching. Also, the drug is effectively used to disinfect the skin with abrasions, cracking, burns, diseases of the mucous system. various bodies, in surgery, obstetrics, urology. Composition of Amident: chlorhexidine bi-gluconate, distilled glycerin, peppermint oil, methylene blue, H2O. In pharmacies, the drug is available in 100 ml glass containers.
  3. Elugel- compact packaging (in the form of a small tube) of a drug produced in the form of a gel. It is prescribed in the course of therapy for colpitis, erosive pathologies of the cervix, for the treatment of a wide range of genital infections. Also, the drug is effective for the disinfection of various wounds, burn lesions, the need for cleaning and disinfection of large areas. skin. The drug is produced on the basis of chlorhexidine bi-gluconate. The medicine is sold in plastic tubes with a capacity of 40 ml.
  4. In pharmacies, you can also buy Chlorhexidine Bi-Gluconate in a glass bottle of 100 - 500 ml, equipped with a special nozzle. This drug is effective in the treatment infectious diseases caused by microorganisms such as gardanella, treponema, chlamydia, ureaplasma and others.

Antiseptic for local application in gynecology

Active substance

Release form, composition and packaging

◊ Suppositories vaginal white or white with a yellowish tint, torpedo-shaped, marbling of the surface is allowed.

Excipients: polyethylene oxide base (polyethylene oxide 1500, polyethylene oxide 400).

5 pieces. - cellular contour packings (1) - packs of cardboard.
5 pieces. - cellular contour packings (2) - packs of cardboard.

pharmachologic effect

Antiseptic drug for local use.

Active towards gram positive and gram negative bacteria- Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis; protozoa- Trichomonas vaginalis; viruses- Herpes simplex types 1 and 2.

Does not violate the functional activity of lactobacilli.

Retains activity (albeit somewhat reduced) in the presence of blood, pus.

Pharmacokinetics

Practically not absorbed from the gastrointestinal tract. After accidental ingestion of 300 mg C max is reached after 30 minutes and is 0.206 μg / l. It is excreted mainly with feces (90%), less than 1% is excreted in the urine.

Indications

- prevention of sexually transmitted diseases (including gonorrhea, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);

— prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment gynecological diseases, before and after diathermocoagulation of the cervix, before intrauterine examinations);

- treatment of chronic exo- and endocervicitis, vaginitis (including non-specific, mixed, trichomonas).

Contraindications

- hypersensitivity to the components of the drug;

- allergic reactions.

Dosage

For prevention sexually transmitted diseases appoint once 1 soup. The drug should be used no later than 2 hours after sexual intercourse.

For treatment appoint 1 soup. 2 times / day for 7-10 days. If necessary, it is possible to extend therapy up to 20 days.

Side effects

Possible: allergic reactions, itching, passing after discontinuation of the drug.

Overdose

Currently, cases of overdose of the drug Hexicon D have not been reported.

drug interaction

Hexicon D is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate

Antiseptic, disinfectant drug.

Price from 260 rub.

Antiseptic, disinfectant drug.

Application- vaginosis, colpitis, prevention of gonorrhea.

Analogues- Depanthenol, Clioron, Macmirror. You can find out more about analogues, their prices, and whether they are substitutes at the end of this article.

Today we will talk about Hexicon candles. What kind of remedy, how does it affect the body? What are the indications and contraindications? How and in what doses is it used? What can be replaced?

What is the drug

Hexicon - vaginal suppositories with antiseptic, antimicrobial action. The drug is prescribed for the treatment and prevention of infectious and inflammatory pathologies of the cervix and vagina.

Active ingredient and composition

1 suppository contains 16 mg of the active substance - chlorhexidine bigluconate.

Auxiliary ingredients in the composition of Hexicon are a mixture of macrogols. These components allow a more uniform distribution of the active substance over the mucous membranes, penetrate deeply into the tissues.

Pharmacological properties

Hexicon is a local antiseptic and disinfectant. The drug is used against genital infections caused by gram-positive and gram-negative bacteria, protozoa and herpes viruses.

Hexion is active against:

  • treponema;
  • gonococci;
  • chlamydia;
  • gardnerell;
  • ureaplasma;
  • bacteroids fragilis;
  • Trichomonas;
  • individual strains of Pseudomonas;
  • Proteus;
  • herpes virus type II.
Viruses, fungi, acid-resistant bacteria are immune to the drug.

Pharmacodynamics and pharmacokinetics

Active substances interact with the structures of microbial cells, disrupt the processes of their vital activity and development. Which leads to the death of pathogenic microflora. At the same time, the functions of beneficial lactobacilli are not violated.

With intravaginal application, the active ingredients are practically not absorbed, systemic absorption is negligible.

Approximately 90% of the drug is excreted from the body with feces, kidneys - less than 1%.

Indications

Candles Hexicon - the main indications for use. A gynecological drug is prescribed to eliminate bacterial pathologies, prevent sexual diseases.

Hexicon - what helps:

  • reducing the risk of infection with gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis, genital;
  • bacterial;
  • nonspecific, mixed trichomonas.

Suppositories are prescribed:

  • before gynecological operations;
  • before abortion and childbirth;
  • before and after diathermocoagulation of the cervix, installation of an intrauterine device;
  • before intrauterine examinations.

Contraindications for use

Hexicon suppositories have few contraindications. The drug is not prescribed for intolerance, increased susceptibility to the components of drugs.

Method of application and dosage

Hexicon candles - instructions for use.

Elimination of infectious pathologies of the genital organs.

1 suppository in the morning and evening. Course duration - 7-10 days.

If necessary, continue therapy after 20 days.

Prevention of venereal diseases. Enter 1 suppository within 2 hours after unprotected intercourse.

In childhood, during pregnancy and breastfeeding

You can use Hexicon suppositories during pregnancy and lactation.

Suppositories are used with caution in the treatment of children. The optimal form for use in pediatrics is Hexicon D.

Side effects

When using suppositories, local allergic reactions mainly occur - burning and itching in the vaginal area. Unpleasant manifestations disappear on their own after treatment is completed.

special instructions

During treatment, you can not drink alcohol.

In the presence of pus or blood, antimicrobial activity is somewhat reduced. Candles are not contraindicated during menstruation.

intimate hygiene external genital organs does not affect the effect of the drug, since the suppositories are administered intravaginally. But before the introduction of the suppository, it is necessary to thoroughly wash off the soap from the mucous membranes and skin.

Candles should be inserted deep into the vagina, preferably to the depth of the index finger. This will prevent the suppository from leaking out and falling out.

Overdose

Cases of overdose have not been recorded.

drug interaction

Vaginal suppositories are dispensed in a pharmacy without a prescription, but before using it, you should consult a doctor and carefully study the annotation.

The material was prepared specifically for the site, the site was edited by the doctor Churilina E.Yu. Specialty: dermatovenereology, general hygiene.

Analogues

Suppository analogues:

  1. Ingredients: Depanthenol, Chlorhexidine.
  2. According to the therapeutic effect - Clomezol, Clioron, Eucolek, Levometrin, Macmirror.

Hexicon ® D, 10 suppositories

Identification and classification

Registration number

International non-proprietary name

Chlorhexidine

Dosage form

Suppositories vaginal

Compound

Composition per suppository

Active substance: chlorhexidine bigluconate solution 20% - 42.6 mg (in terms of chlorhexidine bigluconate - 8 mg);

Excipients: mixture of macrogols: macrogol 400 - 2%, macrogol 1500 - 98%.

Description

Suppositories torpedo-shaped white or white with a yellowish tint. Marbling and the presence of an air rod and a funnel-shaped recess on the cut are allowed.

Pharmacotherapeutic group

Antiseptic

pharmacological properties. Pharmacodynamics

Hexicon ® D - antiseptic drug for local (intravaginal) use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including against Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex II type. Some strains of Pseudomonas spp., Proteus spp. are slightly sensitive to the drug, as well as acid-resistant forms of bacteria, bacterial spores. Hexicon ® D does not violate the functional activity of lactobacilli.

Pharmacokinetics

Systemic absorption with intravaginal use is negligible.

Indications for use

The drug Hexicon ® D, vaginal suppositories, is indicated for local treatment genital infections in children, used in pediatric gynecology in girls from 6 months. and before menarche.

Treatment of vulvovaginitis (including nonspecific, mixed, gonorrheal, trichomonas), bacterial vaginosis.

Prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis), infectious and inflammatory complications in pediatric gynecology (for example, before surgical treatment of gynecological diseases).

Contraindications

Hypersensitivity to the components of the drug

Use during pregnancy and during breastfeeding

It is possible to use the drug during pregnancy and during breastfeeding if the intended benefit to the mother outweighs the potential risk to the fetus or child.

Dosage and administration

Having previously released the suppository from the blister pack, it is introduced into the vagina in the supine position.

For treatment: 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.

For the prevention of sexually transmitted diseases: 1 suppository no later than 2 hours after sexual intercourse.

Side effect

Frequency adverse reactions according to WHO classification: very often (≥10%), often (≥1% and<10%), нечасто (≥0,1% и <1%), редко (≥0,01% и <0,1%), очень редко (<0,01%), частота неизвестна (не может быть определена на основании имеющихся данных).

Rarely: allergic reactions, itching, passing after discontinuation of the drug.

Frequency unknown: severe allergic reactions, including anaphylaxis.

If any of the side effects listed in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

Currently, cases of drug overdose have not been reported.

Interaction with other drugs

Not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose) and soaps when administered intravaginally. The toilet of the external genitalia does not affect the efficacy and tolerability of vaginal suppositories Hexicon ® D, because the drug is administered intravaginally.

special instructions

Hexicon ® D retains activity (albeit somewhat reduced) in the presence of blood, pus. Suppositories have a reduced size, designed specifically for the treatment of girls.

Influence on the ability to drive vehicles and work with mechanisms

The description is up to date 21.11.2014
  • Latin name: Hexicon
  • ATX code: D08AC02
  • Active substance: Chlorhexidine bigluconate (Chlorhexidini bigluconas)
  • Manufacturer: OAO Nizhpharm, Russian Federation

Compound

One suppository Hexicon includes 16 mg Chlorhexidini bigluconas

Part candles Hexicon D includes 8 mg Chlorhexidini bigluconas , as well as a polyethylene oxide base (polyethylene oxide 1500/Polyaethylenoxydum 1500, polyethylene oxide 400/Polyaethylenoxydum 400).

V solution for external use contains 0.5 mg solution Chlorhexidini bigluconas with a concentration of 20%, purified water (Aqua purificata).

in one hundred grams gel contains 0.5 g Chlorhexidini bigluconas and auxiliary components: cremophor - RH 40 (Cremophor RH 40), poloxamer 407 (Poloxamerum 407), purified water (Aqua purificata).

One Hexicon vaginal tablet contains 16 mg Chlorhexidini bigluconas (as a solution Chlorhexidini bigluconas with a concentration of 20%) and auxiliary components: microcrystalline cellulose (Cellulosum microcrystallisatum), pregelatinized corn starch (Amylum maidis), low molecular weight povidone (Povidone), stearic acid (Acidum stearicum), lactose monohydrate (Lactose monohydrate).

Release form

The manufacturer produces the drug in the form of:

  • vaginal suppositories 8 and 16 mg;
  • solution;
  • gel;
  • vaginal tablets 16 mg.

pharmachologic effect

Hexicon belongs to the pharmacotherapeutic group of drugs antiseptic and disinfectant action . Interacting with structures microbial cell , it disrupts vital activity, inhibits development and provokes death pathogenic .

The use of various dosage forms of Hexicon in gynecological practice allows not only to successfully deal with pathogenic microorganisms , but also to carry out the prevention of infectious diseases transmitted by PP.

Pharmacodynamics and pharmacokinetics

Hexicon, which is part of the active ingredient, is a strong disinfectant, the sensitivity to which exhibits a wide range microorganisms , including including Gram (+) and Gram (-) bacteria , protozoa , herpesviruses .

Hexicon is effective against:

  • gonococci (Neisseria gonorrhoeae);
  • pale treponema (Treponema pallidum);
  • chlamydia (Chlamydia spp.);
  • gardnerell (Gardnerella vaginalis);
  • ureaplasma (Ureaplasma spp.);
  • bacteroid fragilis (Bacteroides fragilis);
  • Trichomonas (Trichomonas vaginalis);
  • herpesvirus type II (HSV-2).

Individual strains are characterized by weak sensitivity to the drug. pseudomonas (Pseudomonas spp.) and protea (Proteus spp.). Resistant to its effects are viruses , mushrooms , bacterial spores , acid resistant bacteria .

Thanks to the Hexicon chlorhexidine drug has a number of advantages over others antimicrobial and antiseptics . He:

  • does not violate the natural microflora of the female genital tract and does not affect activity. lactobacilli ;
  • does not cause addiction and resistance to its action in those sensitive to it microorganisms (even with repeated use);
  • licensed for treatment pregnant and lactating women ;
  • retains (albeit to a lesser extent) activity in the presence of spotting and pus.

The effectiveness of suppositories is also ensured by the features of their constituent polyethylene oxide 1500 (Polyaethylenoxydum 1500) and polyethylene oxide 400 (Polyaethylenoxydum 400). These substances provide a more uniform distribution of the active substance over the surface. mucous membrane and deeper penetration into tissues.

In addition, the polyethylene oxide base dehydrates pathogenic microorganisms and cleanses the mucosa from the products of their vital activity accumulating on it.

Hexicon vaginal tablets have been developed as an alternative to suppositories. For some women, they are somewhat more convenient than candles, since they do not increase the volume of secretions and, therefore, do not require the use of additional hygiene products.

Practically not absorbed from gastrointestinal tract , as well as through the skin and mucous membranes when applied topically. Systemic absorption when using Hexicon tablets intravaginally is extremely negligible.

In case of inadvertent ingestion of 0.3 g Cmax is reached after half an hour and is 0.206 µg / l.

The drug is eliminated from the body mainly with the contents of the intestine (90%), less than 1% is excreted by the kidneys.

Indications for use

Candles Hexicon - what are they from?

Candles Hexicon are indicated for prevention sexually transmitted infectious diseases caused by activity sensitive to the action of the drug microflora , for treatment inflammation of the genitals in women, to prevent the development of the inflammatory process and infection of the genital tract before childbirth, gynecological operations, abortion procedures, intrauterine examinations, etc.

Indications for the use of Hexicon D suppositories are children's gynecological diseases .

Indications for the use of solution, gel and vaginal tablets are the same as for suppositories.

Additional indications for the use of the solution

The solution is used as a disinfectant for processing festering wounds and infected burns . In gynecology, surgery and urology, it is used to treat skin infections and mucous .

Dentists prescribe rinses with Hexicon for aphthous stomatitis , gingivitis , inflammatory lesions of periodontal tissues and terminal parts of the respiratory tract .

Additional indications for the use of the gel

Gel Hexicon use for the treatment of inflammatory diseases in gynecology , dentistry and urology . In addition, they are treated with infected areas of the skin.

Contraindications

Contraindications to the appointment of Hexicon are hypersensitivity to its components.

Additional contraindication for the solution -.

Gel and suppositories are used with caution in the treatment of children. The optimal dosage form for a child is Hexicon D suppositories.

Side effects

The most common side effects of candles are, itching and burning into the vagina. These symptoms do not require specific treatment and disappear on their own after stopping the course of treatment.

Hexicon D vaginal suppositories provoke unwanted side effects in less than 0.1% of cases.

Undesirable reactions to the use of the solution are also extremely rare. As a rule, they are expressed in the form allergy symptoms and itching passing after the termination of the course of treatment.

For some, the Hexicon solution causes dry skin of the hands, sticky hands (usually no more than three to five minutes), photosensitivity . Rinses of the oral cavity with them lead to staining of tooth enamel, deposition of tartar, taste disturbances. Gel can also provoke similar phenomena.

Instructions for use Hexicon

Candles Hexicon: instructions for use

Candles are intended for intravaginal use.

For medicinal purposes, twice a day for 7-10 days, one suppository is administered intravaginally. If necessary, the course of treatment is repeated after 20 days.

For a warning sexually transmitted diseases it is recommended to enter one suppository no later than two hours after unprotected intercourse.

Instructions for the use of Hexicon D are similar to the instructions for the use of 16 mg suppositories.

Gel Hexicon: instructions for use

For treatment of inflammatory urological and gynecological diseases the gel should be applied to the affected surfaces twice a day. The duration of treatment can vary from 7 to 10 days.

Infectious dermatological diseases treat by thinly applying the gel to the affected surfaces two or three times a day. How long the treatment will be depends on the clinical situation.

In dental practice, the ointment is used in the form of applications with a multiplicity of 2-3 times a day. The duration of one procedure is from one to three minutes. The duration of the course is determined depending on the clinical situation.

Instructions for use of the solution

The solution is used externally and topically in the form of applications, irrigations and rinses. For one procedure, it is necessary to apply on the affected surface of the skin or mucous membranes from five to ten milliliters of the product with an exposure of one to three minutes 2 or 3 times a day (the solution can be applied on a swab or by irrigation).

For prevention infections , which are transmitted by PP, it is advisable to use Hexicon if the procedure is carried out no later than two hours after sexual contact.

Using a nozzle, the liquid contained in the vial is injected into urethra (both women and men) or vagina . Dose for injection into the urethra for men - from 2 to 3 ml, for women - 1 or 2 ml. In vagina injected from 5 to 10 ml of solution. The nozzle is delayed for 2-3 minutes.

Also, the solution should treat the genitals and the skin of the inner surfaces of the thighs and pubis. It is not recommended to urinate within two hours after the procedure.

At inflammation of the urethra (including complicated ) complex therapy is supposed, which is supplemented by injection for ten days once or twice a day into the urethra of a solution in a volume equal to 2-3 ml (it is recommended to carry out the procedure every other day).

At diseases of the oral cavity appoint rinsing with a solution of the drug. The frequency of procedures is 3-4 per day. The amount of solution required for one procedure is from 5 to 10 ml.

Instructions for use of vaginal tablets

Before use, the tablet is moistened with water and injected into vagina .Daily dose depending on the diagnosis is 1 or 2 tablets. Treatment is carried out within 7-10 days.

For infection prevention , which are transmitted by PP, the tablet, like suppositories, is recommended to be administered within two hours after unprotected intercourse.

Overdose

Since the drug is practically not absorbed from gastrointestinal tract and is not absorbed when applied topically through skin covering and mucous , the likelihood of an overdose of them is considered unlikely.

To date, there is no information on cases of overdose with Hexicon.

Interaction

The effectiveness of the drug is enhanced with simultaneous use with ethanol .

Hexicon should not be used with intravaginally administered preparations containing iodine.

Sanation external genitalia does not affect the efficacy and tolerability of suppositories, since they are applied intravaginally.

Pharmaceutically incompatible with anionic detergents (saponins, Sodium lauryl sulfate, Sodium carboxy methyl cellulose) and soap. Chlorhexidine is inactivated in the presence of soap, therefore, before using the drug, it is necessary to thoroughly wash off soap residues from the skin and mucous membranes.

It is allowed to combine Hexicon with preparations containing a cationic group.

Terms of sale

OTC

Storage conditions

In a dry place, at a temperature not higher than 25°C for tablets, solution, suppositories and not higher than 20°C for gel.

Best before date

special instructions

Hygiene procedures do not affect the efficacy and tolerability of vaginal tablets and suppositories, since the drug in these dosage forms is administered intravaginally.

When using the solution in patients with head and spinal cord injuries as well as in patients with perforation of the tympanic membrane should be avoided getting into the wound.

If the solution accidentally gets on mucous membranes of the eye , they are recommended to be rinsed quickly and very well with water.

Contact with bleaching agents containing in their composition on clothes that were previously in contact with drugs chlorhexidine , provokes the formation of brown spots on them.

An increase in the temperature of the solution causes an increase in bactericidal action . However, at temperatures exceeding 100°C, there is a partial decomposition of the drug.

How to enter candles?

To prevent leakage of the contents after the introduction of the suppository, the woman should lie on the bed, spreading her legs bent at the knee joints. The candle is inserted as deep as possible into vagina index finger (if possible to the depth of the finger).

If the suppository is not inserted deep enough, it may fall out after the woman gets up before it dissolves.

The principle of operation of Hexicon is similar to the principle of vaginal baths. A feature of these candles is that they are driven several times a day, as a result of which the amount of discharge increases significantly. Given this, during the treatment period, daily pads should be changed as often as possible.

Another feature of suppositories is that there is no need to prescribe additional sanitation before their introduction. vagina or douching, which makes their use more convenient than other vaginal suppositories.

An important recommendation for the period of treatment is the exclusion of sexual intercourse. If therapy is carried out against the background of a regular sexual life, then a positive result will not be achieved. There remains a risk of re-infection and as a result, it may be necessary to prescribe drugs not only local, but also systemic.

The use of Hexicon during menstruation

Quite often, questions arise whether it is possible to use suppositories during menstruation and whether it is allowed to be treated with vaginal tablets during menstruation.

The instructions for Hexicon indicate that the use of suppositories and tablets during menstruation is permissible. This is due to the fact that the active substance of the drug retains (albeit to a lesser extent) pharmacological properties in the presence of pus, spotting and other biological fluids.

Hexicon's analogs

Coincidence in the ATX code of the 4th level:

Analogues in composition for Hexicon in the form of a solution and gel are drugs Amident (solution for topical application) and Chlorhexidine in the form of an alcohol solution, solution, concentrate for the preparation of a solution, spray.

According to the mechanism of action, they are closest (cream), (cream), Lavasept (concentrate for preparing a solution), (solution).

Candles and tablets Hexicon have a similar composition with, respectively, candles and tablets Chlorhexidine . Similar drugs according to the mechanism of action for suppositories are (suppositories), Hyposol (spray can), Yodovidone (candles), (candles), (cream, capsules, tablets, suppositories), vaginal suppositories with trichomonacid, vaginal suppositories with eucalimine, Trichomonacid (tablets), (powder, tablets, granules for suspension), Vagiflor (capsules), (suppositories), (cream), (capsules).

Hexicon during pregnancy

All dosage forms manufactured under the Hexicon brand, with the exception of vaginal tablets, are allowed to be prescribed during and during the period. In the instructions for candles Hexicon at pregnancy and lactation it is indicated that this remedy is considered not only effective, but also safe for both mother and child.

As for vaginal tablets, their use is possible if the benefit to the mother outweighs the risk to the fetus.

Candles Hexicon at pregnancy are one of the most commonly prescribed drugs for the treatment and prevention gynecological diseases . The safety of the drug is ensured by its local effect and is confirmed by many years of experience in use.

Acting locally, its active substance practically does not enter the systemic circulation and thus does not pose a threat to the normal development of the child. Therefore, candles are allowed to be used at all stages of pregnancy.

Hexicon effectively affects pathogenic , which are the cause of women's diseases, but at the same time does not provoke any violations of their own cervical erosion . It is advisable to prescribe them in cases where the cause of ulceration is the activity of pathogens transmitted by PP, or inflammatory “female” pathologies.

During pregnancy Hexicon is most often prescribed for bacterial vaginosis when in vagina dominated pathogenic bacteria , and the quantity lactic acid bacteria (lactobacilli) - reduced or these bacteria are completely absent.

Decrease in quantity lactic acid bacteria a pregnant woman in the background bacterial vaginosis may lead to the development vulvovaginal candidiasis (or, in other words, ).

As practice shows, every year cases of combination and is getting bigger. For this reason, it is widely believed that Hexicon candles are effective in thrush .

Candles Hexicon from thrush

Provokes development vulvovaginal candidiasis yeast-like fungus of the genus Candida who, like many viruses , bacterial spores and acid-fast bacteria , immune to the effects chlorhexidine .

So why are these candles prescribed for pregnancy from thrush ? It's all about the reason thrush is uncontrolled growth Candida fungus colonies , which can be provoked, among other things, by the activity of infectious pathogens - gonococci , Trichomonas and others bacteria and protozoa .

In such cases when infection wears mixed, fungal-bacterial character , the expediency of using Hexicon is due to its ability to effectively remove signs of inflammation, reduce tissue swelling and significantly reduce the severity of pain.

To combat the over-proliferated fungus , which is the direct source of the disease, use antimycotic drugs in the form of gels, creams and vaginal tablets (for example, or).

It is important to remember that self-medication - especially during pregnancy - unacceptable, and Hexicon from thrush prescribed only on the basis of a medical examination and the delivery of all necessary tests.

Thus, Hexicon candles are an effective and safe antibacterial agent for local use, but for treatment candidiasis it is recommended to choose drugs that can actively suppress the main culprit of the disease.

A prerequisite for successful treatment is compliance with the requirements of personal hygiene and - in some cases - the preparation of a special dietary menu that involves limiting the amount of food with a high content of carbohydrates in it, and introducing a sufficient amount of fermented milk products into the diet.