Alpha-lipoic acid is a powerful natural antioxidant and has properties that are used in therapy to treat a wide range of diseases. In addition to its antioxidant properties, it helps the body use glucose and therefore has the potential to play a role in blood sugar control.

What is lipoic acid

Lipoic acid, known as alpha lipoic acid or as a dietary supplement called thioctic acid, is a naturally occurring compound that is involved in energy metabolism. It belongs to antioxidants and is present in every cell of the human body. Antioxidants Attack free radicals, waste that is formed during the digestion of food and causes harmful chemical reactions that have a negative effect on cells that damage organs and tissues.

There are other antioxidants as well. For example, vitamin C, as a water-soluble vitamin, "works" only in water, and vitamin E - in fatty tissues. Alpha lipoic acid is a fatty and water-soluble acid. This means that it can "work" throughout the body. The amount of antioxidants, when they suppress free radicals, drops. There is scientific evidence that lipoic acid can restore these antioxidants and reactivate them.

In the cells of the body, alpha-lipoic acid is converted into dihydrolipic acid. There is confusion between alpha lipoic acid and alpha linolenic acid because both are sometimes abbreviated as ALA. Alpha lipoic acid is not the same as alpha linolenic acid, which is an omega-3 fatty acid.

How Lipoic Acid Works

The main role of lipoic acid in the human body is the deactivation of free radicals that are present throughout the body, including salts of heavy metals. They may be a key factor in the development of neurodegenerative diseases such as Alzheimer's disease.

It activates the antioxidant properties of vitamins C and E and promotes the formation of glutathione in the cells of the body, an important coenzyme of the immune system.

The blood-brain barrier is essentially a "watchman" that protects the central nervous system from harmful substances that circulate in circulatory system. It blocks their access to brain cells. But at certain times (stress, toxins, inflammation) this balance is disturbed and harmful substances penetrate the brain tissue and cause serious damage.

Lipoic acid is able to pass through the blood-brain barrier and neutralize harmful and dangerous compounds that can be harmful to health.

Lipoic acid benefits

Lipoic or alpha-lipoic acid has long been considered a vitamin and was referred to as "vitamin N". But it is produced by the body itself and therefore it would not be entirely correct to call it a true vitamin. Rather, it is a vitamin-like substance.

With significant absorbent, antioxidant, anti-inflammatory properties, lipoic acid may provide benefits to human health. Conducted studies show its effectiveness in relation to neurodegenerative diseases, anti-aging and improvement of functions. nervous system. Recently, it is recommended for weight loss and the fight against excess weight.

The main beneficial properties of this acid can be called antioxidant and metabolic properties.

Its antioxidant properties can be called unique and can be attributed to the most powerful compounds with similar properties. It provides antioxidant protection for both the aqueous phase (blood) and fat, and is able to pass through cell membranes, i.e. ensure the protection of every cell and in all parts of the human body.

It activates the work of vitamins C, E, glutathione and coenzyme Q10 and enhances their antioxidant effect.

It is a coenzyme in the energy metabolism of carbohydrates, sugars, proteins and fats. In alpha-lipoic acid deficiency, glucose cannot be converted into energy and ATP ( adenosine triphosphate).

Reduces insulin resistance.

Its ability to promote glutathione synthesis helps protect and improve liver metabolism.

Binds salts of heavy metals and removes them from the body, which is useful in the treatment of poisoning, for example, salts of cadmium, mercury, arsenic.

Protects brain cells from free radical damage.

Reduces the level of cholesterol in the blood.

Protects from radiation. As shown by studies conducted with us in the treatment of children living in areas contaminated with radiation, when taking lipoic acid, there is a decrease in lipid peroxidation in the blood even more than in children living in a prosperous area. In addition, there was an improvement in kidney and liver function.

Indications for the use of lipoic acid

Usually a varied diet is quite capable of satisfying the need for it. However, some conditions may require more alpha lipoic acid. Additionally, it is useful to take it when:

Diabetic neuropathy and other complications associated with this disease;

Glaucoma;

Cardiovascular diseases;

Alzheimer's disease;

Parkinson's disease;

radioactive damage;

cirrhosis of the liver;

Hepatitis;

In diabetes and diabetic neuropathy, it:

Slows down the progression of the disease;

Stabilizes blood glucose levels;

Increases insulin activity, which may reduce the daily dose;

Reduces numbness in limbs;

Improves the functions of the nervous system.

Alpha-lipoic acid may be useful in preventing senile dementia and other forms of dementia, although scientists do not fully confirm its benefit in the prevention and treatment of such diseases. Due to its ability to cross the blood-brain barrier, it is believed to be able to inhibit and eliminate harmful substances that can cause damage to brain cells and improve the overall health and function of the central nervous system. Scientific research in this direction continues.

According to recent studies, a hypothesis has emerged about the possibility of using lipoic acid for the treatment of cancer. Due to its antioxidant properties, it can:

Limit the growth of cancer cells;

Induce apoptosis, i.e. a process that stops the growth and spread of tumor cells, leading to their death.

It is also noted for its benefits in the treatment of:

Chronic fatigue syndrome;

cataracts;

Glaucoma.

Where is lipoic acid found?

Lipoic acid is produced by our body. However, its production and quantity decreases with age. In addition to dietary supplements, there are products that contain this acid and which can become its additional source.

The main such source is beef liver. But you can find a small amount in the kidneys, heart, red meat. Of the vegetables, the most lipoic acid contains:

Green leafy vegetables and especially spinach;

Brussels sprouts;

Broccoli;

Potato;

Tomatoes.

She is in:

Brewer's yeast;

Rice bran.

Lipoic acid and L-carnitine

Lipoic acid and L-carnitine are both powerful antioxidants. Both of these antioxidants can significantly reduce the oxidative effects of free radicals, slow down the aging process, promote cardiovascular health, and improve cognitive function.

Levocarnitine, as well as alpha-lipoic acid, can be synthesized in the human body.

Together, they can:

Relieve mental and physical fatigue;

Improve concentration;

Improve memory;

Relieve anxiety and stress;

Improve the condition of the heart and blood vessels;

Normalize and maintain normal blood pressure;

Slow down the aging process;

Strengthen the antioxidant activity of vitamin C, E and coenzyme Q10.

Contraindications and side effects

Alpha-lipoic acid should not be taken in high doses by people who are deficient in thiamine.

Be sure to consult your doctor if you have:

Liver disease;

Disorders thyroid gland;

You drink a lot of alcohol.

Also, before starting to take diabetics, it is necessary to check the level of sugar in the blood, so as not to cause a sharp decrease in it.

Pregnant and breastfeeding women and children of any age should not take lipoic acid supplements without consulting a doctor.

One of the side effects is an allergic reaction on the skin. Allergies can manifest as swelling of the face, lips, tongue, or throat.

There are suggestions that taking alpha-lipoic acid can cause mineral imbalance and lead to a deficiency of certain mineral salts. However, in clinical research this assumption has not yet been confirmed.

Stop taking it immediately if:

Sharply decreased blood sugar;

There was a headache

Weakness;

confusion of thoughts;

increased sweating;

Irritability;

Hunger;

Dizziness;

An increase in heart rate.

Are common side effects may include nausea and skin rash.

How to take lipoic acid dosage

For preventive purposes and antioxidant protection, a dose of 100 mg will be sufficient. In the treatment of diabetes and HIV infection, the most common conditions for which lipoic acid is taken can be from 300 mg to 600 mg per day.

Take it with meals. After oral intake it is quickly and completely absorbed, and enters the cells.

Learn more about the benefits of lipoic acid in this video.

Lipoic acid (alpha-lipoic acid, thioctic acid, vitamin N) - properties, content in products, instructions for the use of drugs, how to take for weight loss, analogues, reviews. Lipoic acid and carnitine

Thank you

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Lipoic acid is a biologically active substance, which was previously considered vitamin-like, and now belongs to vitamins with medicinal properties. Lipoic acid is also called lipamide, thioctic acid, para-aminobenzoic acid, alpha lipoic acid, vitamin N or berlition. Moreover, the internationally accepted name of the substance is thioctic acid, but this name is not used in the vast majority of cases, so you need to know all its names in order to freely navigate what is at stake. On the basis of this substance, drugs have already been created and successfully used, such as Berlition, Thioctacid, Lipoic acid, etc.

Consider the properties, indications and rules for the use of lipoic acid both from the standpoint of the active substance and from the point of view of drugs containing this compound as an active ingredient. At the same time, to designate lipoic acid as medicinal product we will write its name with a capital (capital) letter, and for the description as an active substance we will indicate the name with a lowercase (small) letter.

Brief characteristics of lipoic acid

According to its physical properties, lipoic acid is a yellowish crystalline powder with a bitter taste and a specific odor. The powder is highly soluble in alcohols and poorly in water. but sodium salt of lipoic acid it dissolves well in water, and therefore it is it, and not pure thioctic acid, that is used as an active substance for the manufacture of medicines and dietary supplements.

Lipoic acid was first obtained and discovered in the middle of the 20th century, but it got into the category of vitamin-like substances much later. So, in the course of research, it was found that lipoic acid is present in every cell of any organ or tissue, providing a powerful antioxidant effect that maintains human vitality at a high level. The antioxidant effect of this substance is universal, since it destroys any kind and types of free radicals. Moreover, lipoic acid binds and removes toxic substances and heavy metals from the body, and also normalizes the state of the liver, preventing its pronounced damage in chronic diseases such as hepatitis and cirrhosis. Therefore, lipoic acid preparations are considered hepatoprotectors.

In addition, thioctic acid has insulin-like action, replacing insulin with its deficiency, due to which the cells receive a sufficient amount of glucose for their vital activity. If there is a sufficient amount of lipoic acid in the cells, they do not experience glucose starvation, since vitamin N promotes the penetration of glucose from the blood into the cells, thereby enhancing the effect of insulin action. Due to the presence of glucose, all processes in cells proceed quickly and completely, since this simple substance provides the necessary amount of energy. It is precisely because of the ability to enhance the effect of insulin and, moreover, to replace this hormone in case of its deficiency, lipoic acid is used in the treatment of diabetes mellitus.

By normalizing the work of various organs and systems and providing all cells with energy, lipoic acid effective in the treatment of neurological diseases, because it helps to restore the structure of tissues. So, when using lipoic acid, recovery after a stroke is much faster and more complete, as a result of which the degree of paresis and deterioration of mental functions is reduced.

Thanks to antioxidant effect lipoic acid helps to restore the structure of the nervous tissue, due to which the use of this substance improves memory, attention, concentration and vision.

Thus, it is clear that lipoic acid is a natural metabolite formed during biochemical reactions and performs very important functions. These functions are monotonous, but provide a fairly wide range of effects due to the fact that the action is in different organs and systems and is aimed at normalizing their work. In general, we can say that lipoic acid increases activity and prolongs the performance of the human body for a long period of time.

Normally, thioctic acid enters the body from foods that are rich in this substance. In this respect, it is no different from other vitamins and minerals that a person needs for normal life. However, this substance is also synthesized in the human body, therefore it is not indispensable, like vitamins. But with age and various diseases the ability of cells to synthesize lipoic acid is reduced, as a result of which it is necessary to increase its intake from the outside with food.

Lipoic acid can be obtained not only from food, but also additionally in the form of dietary supplements and complex vitamins, which is perfect for the prophylactic use of this substance. For the treatment of various diseases, lipoic acid should be used in the form of drugs in which it is contained in high dosages.

In the body, lipoic acid accumulates in the greatest amount in the cells of the liver, kidneys and heart, since these structures are at the highest risk of damage and need a lot of energy to function normally and properly.

The destruction of lipoic acid occurs at a temperature of 100 o C, so moderate heat treatment of products during cooking does not reduce its content. However, frying food in oil high temperature can lead to the destruction of lipoic acid and, thereby, reduce its content and intake in the body. It should also be taken into account that thioctic acid is more easily and rapidly destroyed in a neutral and alkaline environment, but, on the contrary, is very stable in an acidic one. Accordingly, the addition of vinegar, citric acid, or other acids to food during cooking increases the stability of lipoic acid.

The absorption of lipoic acid depends on the composition of nutrients entering the body. Thus, the more carbohydrates present in the diet, the less vitamin N is absorbed. Therefore, to ensure the absorption of lipoic acid, it is necessary to plan the diet in such a way that it contains a significant amount of fat and protein. Lipoic acid is found in the highest quantities in the following foods:

• Bananas;
• Legumes (peas, beans, lentils, etc.);
• Beef;
• Beef liver;
• Mushrooms;
• Yeast;
• cabbage of any kind;
• Leafy greens (spinach, lettuce, parsley, dill, basil, arugula, leushtyan (lovage), etc.);
• Milk and dairy products (sour cream, cream, butter, kefir, cheeses, cottage cheese, yogurt, etc.);
• Pepper;
• kidneys;
• Wheat groats ("arnautka");
• Heart;
• Eggs.

Fruits and vegetables not on this list contain much less lipoic acid.

Vitamin N intake

Adult men and women need to consume 25 - 50 mg of lipoic acid per day, pregnant and lactating mothers - 75 mg, and children under 15 years old - 12.5 - 25 mg. In diseases of the liver, kidneys or heart, the consumption rate of lipoic acid increases to 75 mg per day, regardless of the age of the person, since it is consumed more intensively and faster.

Excess and deficiency of lipoic acid in the body

No pronounced, clearly identifiable and specific symptoms of lipoic acid deficiency in the body have been identified, since this substance is synthesized by the own cells of all tissues and organs, and therefore is constantly present at least in a minimal amount.

However, it was found that with insufficient use of lipoic acid, the following disorders develop:

• Neurological symptoms (dizziness, headaches, polyneuritis, neuropathy, etc.);
• Liver dysfunction with the formation of fatty hepatosis (fatty degeneration of the liver) and a disorder of bile formation;
• Atherosclerosis of vessels;
• metabolic acidosis;
• Muscle spasms;
• Myocardial dystrophy.

There is no excess of lipoic acid, since any excess that enters the body with food or dietary supplements is quickly excreted without any negative effect on organs and tissues.

V rare cases development of hypervitaminosis of lipoic acid is possible with prolonged use of drugs containing this substance. In this case, hypervitaminosis is manifested by the development of heartburn, increased acidity of gastric juice, pain in the epigastric region and allergic reactions.

Lipoic acid and alpha lipoic acid

Lipoic acid and alpha-lipoic acid are different names for the same biologically active substance used to make medicines and dietary supplements. In addition, Lipoic acid and Alpha lipoic acid are also the names of two drugs that contain vitamin N. Thus, it is obvious that there is simply no difference between lipoic and alpha lipoic acid.

Properties and therapeutic effect of thioctic acid

Lipoic acid has the following effect on the human body:

• Participates in the course of metabolic reactions (carbohydrate and fat metabolism);
• Participates in redox biochemical reactions in all cells;
• Supports the work of the thyroid gland and prevents the development of iodine deficiency goiter;
• Provides protection from the negative effects of solar radiation;
• Participates in the production of energy in cells, being necessary component for the synthesis of ATP (adenosine triphosphoric acid);
• Improves eyesight;
• It has neuroprotective and hepatoprotective effects, increasing the resistance of cells of the nervous system and liver to the adverse effects of various environmental factors;
• Normalizes the level of cholesterol in the blood in atherosclerosis;
• Ensures the growth of beneficial intestinal microflora;
• Has a powerful antioxidant effect;
• It has an insulin-like effect, ensuring the utilization of blood glucose by cells;
• Strengthens immunity.

By severity antioxidant properties lipoic acid is compared to vitamin C and tocopherol (vitamin E). In addition to its own antioxidant properties, thioctic acid enhances the action of other antioxidants and restores their activity when it decreases. Due to the antioxidant effect, the cells of various organs and tissues are not damaged longer and perform their functions better, which, accordingly, has a positive effect on the work of the whole organism.

In addition, the antioxidant effect allows lipoic acid to protect the walls of blood vessels from damage, as a result of which cholesterol plaques do not form on them and blood clots do not attach. That is why vitamin N effectively prevents and is used as part of the complex therapy of vascular diseases (thrombophlebitis, phlebothrombosis, varicose veins, etc.).

Insulin-like action lipoic acid lies in its ability to “bring” glucose from the blood into cells, where it is used for energy production. The only hormone in the human body that is able to “bring” glucose into cells from the blood is insulin, and therefore, with its deficiency, a unique phenomenon occurs when there is a lot of sugar in the bloodstream, and the cells starve, because glucose does not enter them. Lipoic acid enhances the action of insulin and can even "replace" it with a lack of the latter. That is why in Europe and the USA lipoic acid is often used in the complex therapy of diabetes. In this case, lipoic acid reduces the risk of developing complications of diabetes (damage to the vessels of the kidneys, retina, neuropathy, trophic ulcers, etc.), and also reduces the dosage of insulin or other hypoglycemic agents used.

In addition, lipoic acid accelerates and maintains the production of ATP in cells, which is a universal energy substrate necessary for the flow of biochemical reactions with energy expenditure (for example, protein synthesis, etc.). The fact is that at the cellular level, energy is used for biochemical reactions strictly in the form of ATP, and not in the form of fats or carbohydrates received from food, and therefore the synthesis of a sufficient amount of this molecule is critical for the normal functioning of the cellular structures of all organs and tissues.

The role of ATP in cells can be compared to gasoline, which is a necessary and common fuel for all cars. That is, for any energy-consuming reaction to take place in the body, it is ATP that is needed to ensure this process (like gasoline for a car), and not any other molecule or substance. Therefore, in cells, various molecules of fats and carbohydrates are processed into ATP in order to provide energy for the necessary biochemical reactions.

Since lipoic acid supports the synthesis of ATP at a sufficient level, it ensures the rapid and correct flow of metabolic processes and cascades of biochemical reactions, during which cells of various organs and systems perform their specific functions.

If an insufficient amount of ATP is produced in the cells, then they cannot function normally, as a result of which various disorders of the work of one or another organ (which suffers most from a lack of ATP) develop. Very often, various disorders of the nervous system, liver, kidneys and heart due to a lack of ATP develop against the background of diabetes mellitus or atherosclerosis, when the vessels become clogged, as a result of which the flow of nutrients to them is limited. But it is from the nutrients that the ATP necessary for the cells is formed. In such situations, neuropathies develop, in which a person feels numbness, tingling and other unpleasant symptoms along the course of a nerve that is in an area of ​​insufficient blood supply.

Lipoic acid in such situations compensates for nutritional deficiencies, ensuring the production of a sufficient amount of ATP, which allows you to eliminate these unpleasant symptoms. That is why vitamin N is used to treat Alzheimer's disease, as well as polyneuropathies of various origins, including alcoholic, diabetic, etc.

In addition, lipoic acid increases oxygen consumption by brain cells and thus improves productivity and efficiency. mental work as well as concentration.

Hepatoprotective action thioctic acid is to protect liver cells from damage by poisons and toxic substances circulating in the blood, as well as to prevent fatty degeneration of the liver. That is why lipoic acid is introduced into the complex therapy of almost any liver disease. In addition, vitamin N stimulates the constant excretion of excess cholesterol in the bile, thereby preventing the formation of gallstones.

Lipoic acid is able to bind salts of heavy metals and remove them from the body, providing detoxifying effect.

Thanks to its ability to strengthen the immune system, lipoic acid effectively prevents colds and infectious diseases.

In addition, lipoic acid is able to maintain the so-called aerobic threshold, or even increase it, which is very important for both athletes and people involved in amateur sports or fitness to lose weight or maintain good physical shape. The fact is that there is a certain threshold at which, during intense aerobic exercise, glucose ceases to be broken down in the presence of oxygen, but begins to be processed in an oxygen-free environment (glycolysis begins), which leads to the accumulation of lactic acid in the muscles, causing pain. With a low aerobic threshold, a person cannot train as much as he needs, and therefore lipoic acid, which raises this threshold, is necessary for athletes and fitness club visitors.

Lipoic acid preparations

Currently, drugs with lipoic acid and dietary supplements (biologically active supplements) are being produced. Medicines are intended for the treatment of various diseases (primarily neuropathies, as well as diseases of the liver and blood vessels), and dietary supplements are recommended for preventive use by practically healthy people. The complex therapy of various diseases can include both drugs and dietary supplements containing lipoic acid.

Medicines containing lipoic acid are available in the form of capsules and tablets for oral administration, as well as in the form of injection solutions. Dietary supplements are available in tablets and capsules.

Medications

Currently, the domestic pharmaceutical market has the following drugs containing lipoic acid as an active ingredient:

• Berlition - tablets and concentrate for the preparation of a solution for intravenous administration;
• Lipamide - tablets;
• Lipoic acid - tablets and solution for intramuscular injections;
• Lipothioxon - a concentrate for the preparation of a solution for intravenous administration;
• Neurolipon - capsules and concentrate for the preparation of a solution for intravenous administration;
• Octolipen - capsules, tablets and concentrate for the preparation of a solution for intravenous administration;
• Thiogamma - tablets, solution and concentrate for infusion;
• Thioctacid 600 T - solution for intravenous administration;
• Thioctacid BV - tablets;
• Thioctic acid - tablets;
• Thiolept - tablets and solution for infusion;
• Espa-Lipon - tablets and concentrate for the preparation of a solution for intravenous administration.

Dietary supplements with lipoic acid

Currently, the following dietary supplements with lipoic acid are available on the pharmaceutical market:

• Antioxidant from NSP;
• Alpha Lipoic Acid from DHC;
• Alpha Lipoic Acid from Solgar;
• Alpha Normix;
• Alpha D3-Teva;
• Gastrofilin Plus;
• Microhydrin;
• Solgar Nutricoenzyme Q10 with Alpha Lipoic Acid;
• Naches Bounty Alpha Lipoic Acid;
• Alpha Lipoic Acid by Now;
• Alpha Lipoid Acid and L-Carnitine by KWS;
• Alpha Lipoic Acid from Doctor's Best;
• Slim lady;
• Turbo Slim alpha lipoic acid and L-carnitine;
• Liver Aid;
• Mega Protect 4 Life etc.

In addition, lipoic acid is contained in the following varieties of multivitamins Complivit and Alphabet, which are also classified as dietary supplements (like other vitamins):

• Alphabet Diabetes;
• Alphabet Effect;
• Complivit Diabetes;
• Complivit Radiance;
• Complivit Trimestrum 1,2 and 3.

Lipoic acid tablets

In tablet form, vitamins Complivit and Alphabet are produced, as well as the following medicines:

• Berlition;
• Lipamide;
• Lipoic acid;
• Octolipen;
• Thiogamma;
• Thioctacid BV;
• Thioctic acid;
• Thiolept;
• Espa Lipon.

Almost all dietary supplements containing lipoic acid are available in the form of capsules.

Indications for the use of drugs and dietary supplements with lipoic acid

Lipoic acid can be used with preventive purpose or as part of the complex therapy of various diseases. For prevention, it is recommended to take drugs and dietary supplements at the rate of 25-50 mg of lipoic acid per day, which corresponds to the daily need of the human body for this substance. As part of complex therapy, the dosage of lipoic acid is significantly higher and reaches 600 mg per day.

WITH therapeutic purpose Lipoic acid preparations are used in the following conditions or diseases:

• Atherosclerosis of the vessels of the heart and brain;
• Botkin's disease;
• Chronic hepatitis;
• Cirrhosis of the liver;
• Fatty infiltration of the liver (steatosis, fatty hepatosis);
• Polyneuritis and neuropathy against the background of diabetes, alcoholism, etc.;
• Intoxication of any origin, including alcohol;
• Increased muscle mass and aerobic threshold in athletes;
• chronic fatigue syndrome;
• Increased fatigue;
• Decreased memory, attention and concentration;
• Alzheimer's disease;
• Myocardial dystrophy;
• muscle degeneration;
• Diabetes;
• To improve vision, including with macular degeneration of the retina and open-angle glaucoma;
• Skin diseases (allergic dermatosis, psoriasis, eczema);
• Large pores and acne marks;
• yellowish or dull skin tone;
• Blue circles under the eyes;

With a preventive purpose lipoic acid preparations can be taken by both completely healthy people and those suffering from any of the above diseases (but in combination with other drugs).

Instructions for use of lipoic acid

Rules for the use of vitamin N for therapeutic purposes

As part of complex therapy or as the main drug for neuropathies, diabetes mellitus, atherosclerosis, muscular and myocardial dystrophy, chronic fatigue syndrome and intoxication, lipoic acid preparations are used in high therapeutic dosages, that is, 300-600 mg per day.

At severe course diseases first, lipoic acid preparations are administered intravenously for 2 to 4 weeks, after which they are taken in the form of tablets or capsules at a maintenance dosage (300 mg per day). With a relatively mild and controlled course of the disease you can immediately take vitamin N preparations in the form of tablets or capsules. Intravenous administration of thioctic acid is used for atherosclerosis and liver diseases only if a person cannot take pills.

Intravenously 300 - 600 mg of lipoic acid is administered per day, which corresponds to 1 - 2 ampoules of the solution. For intravenous injection, the contents of the ampoules are diluted in saline and administered by infusion (in the form of a "dropper"). Moreover, the entire daily dose of lipoic acid is administered during one infusion.

Since lipoic acid solutions are sensitive to light, they are prepared immediately before infusion. While the solution is "dripping", it is necessary to wrap the bottle with foil or other opaque material. Lipoic acid solutions in foil-wrapped containers can be stored for up to 6 hours.

Lipoic acid tablets or capsules should be taken half an hour before meals with a small amount of non-carbonated water (half a glass is enough). The tablet or capsule must be swallowed whole, without biting, chewing or crushing in any other way. The daily dosage is 300 - 600 mg for various diseases and conditions, and is completely taken at a time.

The duration of therapy with lipoic acid preparations is usually 2-4 weeks, after which you can take the drug for 1-2 months in a maintenance dosage - 300 mg once a day. However, in severe cases of the disease or severe symptoms of neuropathy, it is recommended to take lipoic acid preparations at 600 mg per day for 2 to 4 weeks, after which for several months to drink 300 mg per day.

With atherosclerosis and liver diseases lipoic acid preparations are optimally taken at 200-600 mg per day for several weeks. The duration of therapy is determined by the rate of normalization of tests that reflect the state of the liver, such as the activity of AST, ALT, the concentration of bilirubin, cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG).

Courses of therapy with lipoic acid preparations are recommended to be repeated periodically, maintaining an interval between them of at least 3 to 5 weeks.

To eliminate intoxication and steatosis (fatty liver hepatosis), adults are advised to take lipoic acid preparations in a prophylactic dosage, that is, 50 mg 3 to 4 times a day. Children over 6 years of age with steatosis or intoxication are recommended to take 12-25 mg of lipoic acid preparations 2-3 times a day. The duration of therapy is determined by the rate of normalization of the condition, but not more than one month.

How to take lipoic acid for prevention

For prevention, it is recommended to take drugs or dietary supplements with lipoic acid at a dosage of 12-25 mg 2-3 times a day. It is allowed to increase the prophylactic dosage up to 100 mg per day. Tablets or capsules should be taken after meals with a small amount of non-carbonated water.

The duration of prophylactic administration of drugs and dietary supplements of lipoic acid is 20-30 days. Such prophylactic courses can be repeated, but between two subsequent doses of lipoic acid, an interval of at least one month should be maintained.

In addition to the indicated prophylactic use of thioctic acid preparations by practically healthy people, we will consider the option of using athletes who want to increase muscle mass or raise your aerobic threshold. With the speed-strength nature of the load, 100-200 mg of lipoic acid per day should be taken for 2-3 weeks. If exercises are performed to develop endurance (to increase the aerobic threshold), then lipoic acid should be taken at 400-500 mg per day for 2-3 weeks. During periods of competition or training, you can increase the dosage to 500 - 600 mg per day.

Use during pregnancy and breastfeeding

Due to the lack of clear and reliable data on the safety of the use of lipoic acid during pregnancy and breastfeeding, it is recommended to abandon the use of drugs and dietary supplements containing this substance during these periods of a woman's life. Although, theoretically, lipoic acid is a harmless substance both for a pregnant and nursing mother and for a child, therefore, if necessary, you can take preparations containing this substance, but do this strictly under the supervision of a doctor.

special instructions

At the beginning of the use of lipoic acid with neurological diseases it is possible to increase unpleasant symptoms, since there is an intensive process of restoration of the nerve fiber.

Alcohol significantly reduces the effectiveness of treatment and prevention with lipoic acid preparations. In addition, a large amount of alcohol can provoke a sharp deterioration in a person's condition.

When using lipoic acid with diabetes it is necessary to constantly monitor the level of glucose in the blood and, in accordance with it, adjust the dosage of sugar-lowering drugs.

After intravenous injections lipoic acid, a specific smell of urine may appear, which does not have any important significance, or an allergic reaction may develop, proceeding in the form of itching and malaise. If an allergy develops in response to the introduction of a solution of lipoic acid, then such use of the drug should be stopped and switched to taking tablets or capsules.

Too fast intravenous administration lipoic acid solutions can cause heaviness in the head, convulsions and double vision, which pass on their own and do not require discontinuation of the drug.

Any dairy products should be consumed 4 to 5 hours after ingestion or injection of lipoic acid, as it impairs the absorption of calcium and other ions.

Overdose

An overdose of lipoic acid is possible when taking more than 10,000 mg in one day. The risk of developing an overdose of vitamin N increases significantly with the simultaneous use of alcohol and, accordingly, this may occur when taking a dosage of less than 10,000 mg per day.

An overdose of lipoic acid is manifested by convulsions, lactic acidosis, hypoglycemia (low blood sugar), bleeding, nausea, vomiting, headaches, anxiety, confusion, and bleeding disorders. With a milder overdose, only nausea, vomiting and headaches may occur. However, with any overdose of lipoic acid, a person should be hospitalized, gastric lavage should be performed, a sorbent given (for example, activated charcoal, Polyphepan, Polysorb, etc.) and the normal functioning of vital organs should be maintained.

Influence on the ability to control mechanisms

Lipoic acid does not affect the functions of the central nervous system, and in some cases even improves them, therefore, while taking medications and dietary supplements containing this substance, you can engage in any activity that requires a high speed of reactions and concentration.

Interaction with other drugs

The effects of lipoic acid are enhanced when combined with B vitamins and L-carnitine. And lipoic acid itself enhances the action of insulin and hypoglycemic drugs (for example, Glibenclamide, Gliclazide, Metformin, etc.).

Alcohol reduces the therapeutic effect of lipoic acid and increases the risk of developing side effects or overdose.

Solutions for injection of lipoic acid are incompatible with solutions of glucose, fructose, Ringer's and other sugars.

Lipoic acid reduces the severity of the action of Cisplastin and preparations containing metal compounds (for example, iron, magnesium, calcium, etc.). The intake of lipoic acid and these drugs should be separated in time by 4 to 5 hours.

Lipoic acid for weight loss

Lipoic acid itself does not contribute to weight loss, and the common belief that this substance helps to get rid of excess weight, is based on its property to lower blood sugar levels and stop the feeling of hunger. That is, due to the intake of lipoic acid, a person does not feel hunger, as a result of which he can control the amount of food absorbed and, thereby, lose weight. In addition, stopping hunger makes it relatively easy to tolerate diets, which, of course, lead to weight loss.

Normalization of blood sugar levels leads to an improvement in fat metabolism, which, of course, has a positive effect on overall well-being and condition, and can also contribute to weight loss.

In addition, the intake of thioctic acid leads to the complete processing of carbohydrates eaten into energy, thereby preventing the appearance of new fat deposits. A similar effect can also only indirectly help a person lose weight. Also, lipoic acid binds and removes toxic substances from the body, making the process of losing weight easier and faster.

Thus, it is clear that lipoic acid itself does not cause weight loss. But if you take lipoic acid as a supplement to a sensible diet and exercise exercise this will lead to faster weight loss. For this purpose, it is rational to use thioctic acid in the form of dietary supplements, which also often additionally contain L-carnitine or B vitamins, which enhance the effect of lipamide.

In order to reduce weight, lipoic acid should be taken 12-25 mg 2-3 times a day after meals, as well as before or after training. The maximum allowable dosage of lipoic acid that can be taken for weight loss is 100 mg per day. The duration of the course of using lipoic acid for weight loss is 2 to 3 weeks.

Lipoic acid and carnitine

Carnitine enhances the effect of lipoic acid, and therefore, in many dietary supplements, both of these substances are present simultaneously. Most often, lipoic acid in combination with carnitine is used in dietary supplements that promote weight loss, and are also designed to increase endurance for people involved in sports.

Side effects and contraindications for use

• Hypersensitivity or allergic reactions to the components of drugs or dietary supplements;
• Age under 6 years old;
• Pregnancy;
• Period breastfeeding;
• Gastritis with high acidity of gastric juice;
• peptic ulcer or duodenum in the acute stage.

Lipoic (alpha-lipoic) acid - reviews

Most reviews of alpha-lipoic acid (from 85 to 95%) are positive, due to the noticeable effects of the drug. Often, lipoic acid is taken for the purpose of losing weight, and reviews regarding this aspect of use are also positive in most cases. So, in these reviews it is noted that lipoic acid helps women or men well to budge weight, which for a long time is at the same level, despite diet or regular exercise. In addition, the reviews indicate that lipoic acid accelerates weight loss, but subject to diet or exercise.

Also, lipoic acid is often taken to improve vision and, according to reviews, it works great, because the veil and nebula before the eyes disappear, all surrounding objects are seen clearly and clearly, the colors are juicy, bright and saturated. In addition, lipoic acid reduces eye fatigue with constant eye strain, for example, working at a computer, monitors, with papers, etc.

The third most common reason people take lipoic acid is liver problems, such as chronic diseases, opisthorchiasis, etc. In this case, lipoic acid normalizes general well-being, relieves pain in the right side, and also eliminates nausea and discomfort after eating fatty and plentiful food. In addition to eliminating the symptoms of liver disease, thioctic acid improves the condition of the skin, which becomes smoother, firmer and lighter, the yellowish tint and fatigue disappear.

Finally, many people take lipoic acid simply to make themselves feel better as a vitamin-like substance and a powerful antioxidant. In this case, the reviews indicate a variety of positive effects that appeared after taking vitamin N, such as:

• Energy appears, the feeling of fatigue decreases and working capacity increases;
• Improves mood;
• Bags under the eyes disappear;
• Fluid excretion improves and edema is eliminated;
• The concentration of attention and the speed of thinking increase (in this the effect of lipoic acid is similar to Nootropil).

However, in addition to positive reviews about lipoic acid, there are also negative ones, usually due to the development of poorly tolerated side effects or the lack of the expected effect. So, among the side effects, hypoglycemia most often develops in people, provoking drowsiness, dizziness, headaches and a feeling of trembling limbs.

Price in pharmacies

Price various drugs lipoic acid varies. Currently, in pharmacies in Russian cities, prices for drugs containing lipoic acid are as follows:

• Alpha lipoic acid from Solgar -capsules 707 - 808 rubles;
• Berlition - tablets - 720 - 850 rubles, ampoules - 510 - 956 rubles;
• Lipoic acid - tablets - 35 - 50 rubles;
• Neurolipon - ampoules - 171 - 312 rubles, capsules - 230 - 309 rubles;
• Octolipen - capsules - 284 - 372 rubles, tablets - 543 - 747 rubles, ampoules - 355 - 467 rubles;
• Thiogamma - tablets - 880 - 2000 rubles, ampoules - 217 - 2140 rubles;
• Thioctacid 600 T - ampoules - 1399 - 1642 rubles;
• Thioctacid BV - tablets - 1591 - 3179 rubles;
• Thiolept - tablets - 299 - 930 rubles;
• Thiolipon - a concentrate for the preparation of a solution for intravenous administration;
• Nicotinic acid (vitamin B3, vitamin PP, niacin) - description and instructions for use (tablets, injections), what products contain, how to use for weight loss, for hair growth and strengthening, reviews

Without vitamins it is difficult to maintain good health, but there are substances without which the body cannot function at all. These include, which is otherwise called vitamin N. Her beneficial features were discovered relatively recently, in the 60s.

The benefits and harms of lipoic acid

1. It should be noted right away that an overdose of lipoic acid does not manifest itself in the body. This substance is natural, therefore, even when using large dosages in separate form negative effects in the body will not occur.
2. Lipoic acid is found in every living cell. It is a powerful antioxidant, participates in metabolic processes, stores other antioxidants in the body and enhances their effectiveness. With a normal content of this substance in the body, each cell receives a sufficient amount of nutrition and energy.
3. Vitamin N (lipoic acid) destroys free radicals that destroy cells, as a result of which they begin to age. It removes salts of heavy metals from the body, supports the functioning of the liver (even with its diseases), helps to restore the nervous system and immunity.
4. In combination with other beneficial substances, vitamin N improves memory and increases concentration. It restores the structure of the brain and nerve tissues. It was found that under the influence of this vitamin, significantly improve visual functions. The content of lipoic acid is very important for the normal functioning of the thyroid gland. This substance is able to relieve chronic fatigue and increase activity.
5. Alpha lipoic acid is very beneficial for weight loss. It affects the areas of the brain responsible for appetite, resulting in reduced hunger. It also reduces the liver's tendency to store fat and improves absorption. Thus, its level in the blood decreases. Lipoic acid stimulates energy expenditure, which is also important for weight loss.
6. Lipoic acid has shown itself well in bodybuilding. Heavy workloads mean high nutrient requirements, and alpha lipoic acid provides the body with energy and replenishes glutathione, which is quickly depleted during exercise. Athletes are encouraged to take this substance in its free form.
7. Official medicine uses vitamin N as a powerful drug for the treatment of alcoholism. Toxic substances disrupt the functioning of almost all body systems, and vitamin N allows you to normalize the condition and minimize all pathological changes.

Where is lipoic acid found?

Due to the great benefits of lipoic acid, it is important to know what it contains. It is worth noting that vitamin N is found in almost all cells. human body. But with poor-quality nutrition, its reserves are greatly depleted, which manifests itself in weak immunity and poor health. To make up for the body's lack of this vitamin, a normal healthy diet is enough. The main sources of lipoic acid are: heart, dairy products, yeast, eggs, beef liver, kidney, rice and mushrooms. If desired, you can use vitamin N in a separate form.

The use of lipoic acid has a very beneficial effect on the body. Vitamin N is primarily needed for people with chronic fatigue, weakened immune systems, poor health and mood. In combination with physical activity and healthy eating the result will exceed expectations.

Lipoic acid appears as a light yellow powder and tastes bitter. This sulfur compound with a fatty acid is produced in the human body, but more and more doctors recommend its additional intake.

The supplement gives energy, helps to lose weight, restores health internal organs, promotes rejuvenation and is practically harmless. It is worth it to take a closer look, to figure out in which cases it can be taken with maximum benefit for yourself. Why exactly lipoic acid, why women need such therapy, in what cases it should be avoided and how to choose the right drug, we will tell in this article.

Properties

Lipoic acid is involved in metabolism, by the way it influences the processes occurring in the body, it is easiest to compare it with vitamins from the B-group. It helps to regulate metabolic and fat processes in the body, eases the load on the liver and improves its functioning, removes decay products, toxins and toxins from the body. For this property, it is used in severe poisoning for the rapid removal of hazardous substances. Participates in cholesterol metabolism, helps to lose weight due to lipotropic properties.

Lipoic acid (also called Alpha-lipoic or thioctic, vitamin N, lipamide) is an internal one that binds unnecessary free radicals. Lipamide reduces the amount of glucose in the blood and increases glycogen stores.

Inside the cells of the body, it affects the enzymatic reactions, increases the energy received.

The substance controls decay, contributing to the effective absorption of all necessary substances and removes unnecessary residues from the body.

Lipamide preserves the health of DNA structures, preserves youth and functions of the body.

This acid is formed in the human body, actively takes part in metabolic processes. With age, its production decreases.

Release form, composition

However, there are quite a lot of dietary supplements based on lipoic acid, including imported ones. Their prices fluctuate depending on the quantitative content in mg from 500 to 3000 rubles.

In pharmacies, lipoic acid is sold in tablets (12.25 mg), in 300 mg capsules, or in injection solutions. For example, 50 tablets of 25 mg can be bought for 48 rubles, without overpaying for the necessary medicine in a beautiful package with expensive delivery.

Indications for use

1. As one of the components in the complex therapy of atherosclerosis.
2. Diabetes.
3. Severe poisoning associated with liver damage: poisoning with wild mushrooms, heavy metals, drug overdose.
4. With liver damage: chronic and viral hepatitis, cirrhosis.
5. Chronic inflammation of the pancreas.
6. Heart failure.

Adult women under the age of 35 consume 25-50 mg of acid per day, during pregnancy, breastfeeding consumption rises to 75 mg. For girls under 15, 12 to 25 mg is enough. A healthy body produces this amount on its own, and does not need additional supplements.

Method of reception: The tablet or capsule is taken on an empty stomach on an empty stomach and washed down with plenty of clean water. Tea, juice, dairy products neutralize its effect. You can eat one hour after taking.

Lipoic acid for women over 50

The need for acid increases significantly with age. From 40 to 50 years old, the antioxidant system is depleted and there is a need to fight free radicals that lead to aging and general wear and tear of the body. The daily dose for prevention is 60-100 mg per day.

With age, the number of diseases of internal organs accumulates, kidneys wear out, the cardiovascular system and other important systems. Under these conditions, lipoic acid is consumed at a high rate, which leads to the need for additional intake.

Oxidative stress, living in big cities, unhealthy eating habits, junk food and unhealthy drinks also require an additional dose of lipoic acid. The daily norm can be 200-300 mg.

In a situation of heavy physical activity, the menu is administered from 100 to 600 mg per day.

Daily norms of 300-600 mg are used in the treatment of age-related diseases such as Alzheimer's disease, diabetes, neuropathy, liver disease.

Acid is introduced into the composition of complexes that facilitate the course of menopause. During this period, bone loss begins, the supplement increases bone mineral density. According to experts, all age patients who tolerate it well should add it to the diet to combat free radicals and as a preventive measure.

For infertility in women

With infertility in women, lipoic acid will help the couple conceive a healthy baby. In men, it improves the quality of sperm, which is important for more confident conception and development of the embryo. Currently, more and more gynecologists include the drug in the regimen of taking vitamins at the time of planning and preparing the body for pregnancy. Lipoic acid improves the effect of other drugs, cleanses the body of toxins, reduces chronic inflammation.

Important: during the onset of pregnancy, anemia is dangerous for the fetus, and doctors are trying to maintain and raise the level of iron in the body of the expectant mother. Taking alpha-lipoic acid lowers the level of iron, so it is advisable to refuse it during pregnancy. For a general improvement in the condition of the body, the course is drunk at the planning stage; during pregnancy, admission is possible only if necessary, as directed by a doctor.

Application for wrinkles

Antioxidant properties can be fully manifested when it comes to fighting the visible signs of age. The properties of the acid are far superior to such recognized antioxidants as cosmetic vitamins E, C.

Enrichment of cosmetic compositions with lipoic acid reduces pigmentation, removes circles under the eyes, eliminates fine mimic wrinkles, smoothes the surface, makes the skin more dense, and the tone is even and natural.

Lipoic acid for weight loss

Despite the fact that the drug is not considered a means for weight loss, it is most often used during weight loss.

It is believed that due to the intake of the supplement, there is a decrease in appetite, the mood is evened out, the fat reserve burns faster and the craving for sweets decreases.

Myths and truth about alpha lipoic acid:

1. Decreased appetite. The substance normalizes blood sugar levels. Thanks to this action, the appetite is reduced and it becomes much more comfortable to endure the diet.
2. Normalization carbohydrate metabolism . Due to the intensive burning of reserves, the process of losing weight is accelerated, the tone increases, and a surge of energy is felt for further activity.
3. Lipotropic effect. By eliminating toxins and improving liver function, well-being improves.

We can conclude: acid alone will not make the body lose weight. But if you turn on the process of losing weight, choosing the right diet and connecting sports activities, alpha lipoic acid will become a comfortable and pleasant addition.

It is taken 25 mg before or immediately after sports loads as well as after meals. The maximum per day is 100 mg, the time of admission is 3 weeks.

• rice, unpolished, brown, wild;
• green vegetables: broccoli, spinach or Brussels sprouts;
• peas;
• tomatoes;
• by-products: liver, kidneys.

Contraindications and side effects

1. Individual sensitivity or intolerance.
2. preschool age.
3. Acidity, suspicion or identified ulcer, gastritis.
4. iron deficiency.
5. Allergic reaction.

Very important: in the process of taking alpha-lipoic acid, you will have to stop taking any alcohol, even dosage forms.

In cases of exceeding the intake rate (10,000 mg at a time or in combination with alcohol), the following symptoms may appear: convulsions, severe heartburn and abdominal pain, blood clotting is disturbed, hypoglycemic coma is possible.

There is no antidote for lipoic acid, in cases of overdose, relieve the condition and monitor symptoms, do gastric lavage, induce vomiting, give Activated carbon.

Interaction with other drugs

• Cisplatin: decreased efficacy of cisplatin.
• Insulin and hypoglycemic agents: the action of insulin, as well as drugs for hypoglycemia, is enhanced.
• : the effect of carnitine is enhanced.
• ethanol: the action of the acid is weakened or disappears.
• Complete incompatibility: ethanol, Ringer's solutions, dextrose.

Important: acid removes magnesium and iron from the human body, it is advisable to supplement your diet with the necessary supplements for those who suffer from anemia or need magnesium supplements for stable cardiac activity.

Possible analogues

In pharmacies, you can find analogues of the usual drug called “Lipoic acid” in the form of tablets, capsules and injection solutions. They contain the same substance, only the design, the degree of purification and dosage, and the price differ.

It is impossible to find another drug with the same properties, since it is an endogenous substance that is produced by the body itself.

Popular analogues:

• berlition;
• octolipene;
• thiogamma;
• thioctacid;
• neurolipon;
• thiolept;
• espa-lipon;

The modern chemical industry produces two analogues of the additive with a mirror molecule, right and left. The name or description of the drugs contains the Latin letters L or R. The “right” option is more expensive, but completely identical to the substance that is produced by the human body itself. When choosing such a drug, you need to halve the recommended dosages, as it is easily absorbed.

The “left” version acts more weakly, is absorbed worse and has almost no effect on the sensitivity of cells to insulin.

In the case of alpha lipoic acid, the drug seems to be very friendly and natural to the human body, but self-administration should be avoided. Consultation with your doctor will help you make the right decision, choose the right dosage and the appropriate form of administration.

The description is up to date 23.04.2015

• Latin name: Lipoic acid
• ATX code: A16AX01
• Active substance: Thioctic acid
• Manufacturer: URALBIOPHARM, MARBIOPHARM (Russia)

Compound

The tablet contains 12 or 25 mg of active ingredient. In 1 ampoule 10 ml of solution.

Release form

Lipoic acid is produced in the form of tablets in a special film shell in a package of 10, 50, 100 pieces.

pharmachologic effect

The active ingredient is endogenous, which is able to bind aggressive free radicals . Alpha-lipoic acid acts as a coenzyme in the transformation of substances that have pronounced antioxidant effects.

Such substances are able to exhibit protective, protective functions in relation to cells, protecting them from the aggressive effects of reactive radicals, which are formed during intermediate metabolism, or at the time of the breakdown of foreign exogenous substances (including heavy metals).

The active substance is involved in mitochondrial substances inside the cell. By stimulating the utilization of glucose, thioctic acid is able to synergize with. In patients with, a change in the level of pyruvic acid concentration in the blood is recorded.

According to the mechanism and nature of the biochemical effect, the active substance is similar to. The active substance has a lipotropic effect, which manifests itself in the acceleration of utilization processes in relation to lipids in the hepatic system. Lipoic acid is able to stimulate the transfer of fatty acids from the hepatic system to various tissues in the body.

For a drug, the nature of the detoxification effect is when salts of heavy metals enter the body and in case of other poisonings. Thioctic acid changes cholesterol metabolism, improves the general and functional state of the liver.

Pharmacodynamics and pharmacokinetics

Indicators of pharmacokinetics and description of pharmacodynamics in the medical literature are not found.

Indications, use of Lipoic acid

The drug is widely used in the treatment of hepatic pathology, the nervous system, and intoxication, diabetes mellitus, to alleviate the course of oncological diseases.

Main indications:

• against the background of alcoholism;
• chronic;
• acute liver failure;
• intoxication with heavy metals, sleeping pills, carbon, carbon tetrachloride, mushrooms;
• increasing viral hepatitis jaundice ;
• diabetic polyneuritis ;
• alcoholic polyneuropathy;
• pale toadstool poisoning;
• fatty hepatic degeneration;
• dyslipidemia;
• coronary.

During the course of treatment, the drug acts as a corrector and synergist to prevent the development of a "withdrawal syndrome", a smooth decrease in the dose of glucocorticosteroid.

Lipoic acid for weight loss

The mechanism of action of the active substance allows the use of the drug to get rid of excess weight. The effect is more pronounced with simultaneous active sports. Lipoic acid is able to trigger the fat burning mechanism, but it is not possible to burn absolutely all excess fat on its own, therefore, intense physical activity is required.

Muscle tissue "attracts" nutrients during training, and thioctic acid can increase endurance by increasing fat burning and increasing the overall effectiveness of physical activity. Simultaneous compliance with the diet allows you to achieve the greatest result.

Dosage of Lipoic Acid for Weight Loss

Usually 50 mg of the drug is enough. The minimum threshold is 25 mg. The most effective time of taking the drug to achieve maximum results in the fight against excess weight:

• before or immediately after breakfast;
• at the last daily meal;
• after training, physical activity.

Reviews

The drug works well when dieting and at the same time an active combination of classes in the gym. On thematic forums, users discover a little secret: the drug works better when taking carbohydrate foods (semolina or buckwheat porridge, dates, honey, pasta, rice, peas, beans, bread products).

Lipoic acid in bodybuilding

Quite often in bodybuilding, thioctic acid is combined with Levocarnitine ( , ). This is a relative of B vitamins, and is able to activate fat metabolism. Levocarnitine releases fat from cells, stimulating energy consumption.

Contraindications

Age limit - up to 16 years.

Side effects

• epigastric pain;
• nausea;
• anaphylactic reactions;
• skin rashes;
• vomit;
• convulsions;
• boost ;
• disorders of glucose metabolism hypoglycemia );
• headache by type;
• propensity to ( with functional disorders);
• point hemorrhages;
• diplopia ;
• difficulty breathing.

Lipoic acid, instructions for use (Method and dosage)

300-600 mg of thioctic acid is administered daily intravenously, which corresponds to 1-2 ampoules of 10 ml and 1 ampule of 20 ml with a concentration of 3%. The duration of therapy is 2-4 weeks, after which the treatment is continued with a tablet form at a daily dose of 300-600 mg.

Instructions for use Lipoic acid tablets

Inside 30 minutes before meals. Tablets should not be broken or chewed. Daily dose: 1 tablet 1 time per day (300-600 mg). The therapeutic effect is achieved when taking 600 mg per day. In the future, the dose can be halved.

At diseases of the hepatic system prescribe tablets: up to 4 times a day, 50 mg for a month. A second course can be carried out after 1 month.

Therapy diabetic neuropathy and alcoholic polyneuropathy: start with intravenous injections with the transition to a tablet form of 600 mg per day.

Overdose

The clinical picture consists of the following negative manifestations:

• diarrhea syndrome;
• headache;
• nausea;
• epigastric pain;
• hypoglycemia.

Treatment is post-syndromic.

Interaction

The drug is able to enhance the effects of glucocorticosteroid medicines. Suppression of activity is noted Cisplatin . The drug enhances the effect of hypoglycemic agents (oral forms), insulin.

In case of urgent need for the use of drugs, it is recommended to maintain a certain time interval (at least 2 hours). Metabolites of ethanol and he himself weaken the effect of thioctic acid.

Terms of sale

Prescription leave.

Storage conditions

Transportation and storage of tablets and solution is allowed only if the temperature regime is observed - up to 25 degrees.

Best before date

special instructions

The main metabolic pathways are oxidation and conjugation (source - Wikipedia).

Benefit and harm

Lipoic acid is a natural antioxidant and vitamin. It contributes to the normalization and acceleration of metabolic processes, stimulates the pancreas, removes toxins from the body, lowers blood sugar levels, improves visual perception, has a beneficial effect on the functioning of the heart, reduces and helps to normalize blood pressure.

Against the background of the use of Lipoic acid, there is a decrease in the severity of negative reactions that occur after treatment in oncological patients.

The drug has a beneficial effect on the condition of nerve endings damaged as a result of diabetes. Rarely, against the background of the use of the drug, negative reactions appear.

Similar drugs

Coincidence in the ATX code of the 4th level:

Drugs containing Thioctic acid:

• Alpha Lipon;

children

Thioctic acid in pediatric practice can be used from the age of 16.

During pregnancy and lactation

Lipoic acid is not used.

It is also a contraindication.

Lipoic Acid Reviews

Lipoic acid reviews for weight loss

There are a variety of reviews. Someone felt absolutely no effect, maintaining their weight, despite the regular use of the medication. Some users note that taking Lipoic Acid, combined with intense cardio and dietary intake, can significantly reduce weight without harming their health.

Patients suffering diabetes, note that the medication can reduce the severity of negative reactions of hypoglycemic agents (in some cases it was possible to reduce the dosage) and improve overall well-being.

Lipoic acid price, where to buy

Most often, the drug is purchased for weight loss. You can buy Lipoic acid in a pharmacy in Russia for 50 rubles.

The price of Lipoic acid in Ukraine is 20 UAH, in Minsk 200 thousand Belarusian rubles.

• Internet pharmacies in Russia Russia
• Internet pharmacies in Ukraine Ukraine
• Internet pharmacies of Kazakhstan Kazakhstan

ZdravCity

Naw Foods Alpha Lipoic Acid Caps. 598.45 mg №60 (bad) NOW International

Alpha Lipoic Acid 100 mg. Evalar ANTI-AGE caps. 30 pcs. 1.1 g each Evalar CJSC