Iodine solution for external use. How to apply iodine? Instructions for use

What is the role of iodine in our body? Many of us are used to seeing this medicinal product how antiseptic pharmaceutical industry. In fact, it belongs to the group of useful trace elements that are responsible for a huge number of functions in our body.

A low level of this substance entails the appearance of a hormonal imbalance. This affects the emotional and physical state of a person.

Composition and indications for use

The composition of the drug consists of potassium iodide and ethanol. These components are a solid molecular lattice. The liquid has a purple hue and a pungent odor. When applied externally, it has an antiseptic effect, as a result of which up to 95% of pathogenic microflora is destroyed.

The use of iodine inside has a positive effect on work thyroid gland. The composition helps to enhance the processes of dissimilation, stimulates the production of the hormone terrotoxin, and also starts the processes of tissue metabolism.

An incorrectly selected dosage can provoke an excessive accumulation of a radioactive substance in the tissues of the thyroid gland. Here, impaired production of vital hormones is noted. This entails the development of pathological processes that can cause ovarian or pituitary dysfunction.

WHAT IS IODINE USEFUL FOR THE HUMAN BODY?

The drug is intended for patients with the following symptoms:

  • infectious - inflammatory processes on the mucous membranes;
  • neuralgia;
  • myositis;
  • syphilis;
  • atherosclerosis of the vascular system;
  • excess cholesterol;
  • laryngitis;
  • intoxication of the body with heavy metals;
  • ozena;
  • disease of the heart system.

IMPORTANT: Before starting therapeutic treatment, it is recommended to seek the help of a medical doctor. The specialist will select the optimal dosage based on clinical indications and medical tests. An incorrectly selected dose can provoke the emergence of new pathological foci in the body.

How iodine is mined and obtained

What are trace elements of iodine obtained from? To date, there are several ways to obtain potassium iodide on an industrial scale. Each of them is distinguished by its technology and the resulting volume.

HOW IS IODINE PRODUCED? There are several methods for extracting a useful microelement. These include:

Processing of natural raw materials. Sea kelp is used here. It has been scientifically proven that 1 ton of dried algae contains up to 6 kg of iodine, while sea water is saturated with only 50 mg. Until the end of the 70s of the nineteenth century, this method of obtaining a natural microelement was considered one of the best;

Obtaining iodine from saltpeter waste. They contain up to 0.5% iodized minerals and potassium iodide. This method of obtaining trace elements began to be used from the middle of 1867. The main advantage of this method was its minimal cost. As a result of this, he received wide popularity among manufacturers around the world;

Extraction from natural solutions. Salt is used for this. sea ​​water or fluid from oil sumps. These solutions contain up to 50 mg/l of iodide. In oil solutions, up to 100 mg / l of liquid is fixed;

Ionic iodination. This method of extraction is based on chemical reactions, as a result of which the selective absorption of iodinated molecules is noted.

Contraindications and side effects

There are a number of medical contraindications to the use of this drug. For example, dry iodine often causes individual intolerance to one of the components of the composition. As a result of this, a person has a strong allergic reaction in the form of redness and rashes.

It is forbidden to use iodine with water for people with the following diseases. These include:

  • duodenal ulcer;
  • diabetes;
  • nephrosis;
  • tuberculosis of the kidneys and lungs;
  • furunculosis;
  • diathesis of the hemorrhagic environment;
  • hives;
  • acne;
  • acne.

Improper use of a radioactive iodine solution can provoke the occurrence of adverse reactions in the body. These include:

  • angioedema;
  • lacrimation;
  • local application is accompanied by reddening of the skin;
  • hives;
  • strong salivation;
  • increased sweating;
  • tachycardia;
  • diarrhea;
  • increased nervousness.

If such symptoms are detected, it is necessary to seek appropriate help as soon as possible.

Where is the element found?

In the periodic table, iodine is located at number 53. This chemical variety of non-metal under normal conditions is a dark purple crystals that have a sharp and specific smell. This substance belongs to the group of active collagens.

Get today daily dose substances can be from food. In some of them, the iodine content can reach the maximum permissible level. The excess content of this trace element affects the psycho-emotional state of a person. He becomes too irritable or, conversely, passive.

Foods high in iodide include:

  • a fish;
  • sea ​​shellfish;
  • crabs;
  • squids;
  • kelp;
  • green apples;
  • sea ​​herring;
  • hard cheese;
  • dairy products;
  • mushrooms.

Foods that do not contain iodine include:

  • sugar;
  • canned goods;
  • fruit jelly;
  • paste.

INSTRUCTIONS
on medical use drug

Р №002591/01-2003

Tradename: Iodine

Composition:

water-alcohol solution containing 5 g of iodine, 2 g of potassium iodide, equal amounts of water and ethyl alcohol 95% up to 100 ml.

Description: transparent liquid of red-brown color, with a characteristic smell.

Pharmacotherapeutic group:

antiseptic.

Pharmacological properties:

alcohol iodine solution contains elemental iodine, which, upon contact with the skin or mucous membranes, turns into iodide, partially volatilizes from the surface due to volatility and the presence of ethyl alcohol. It has a quick bactericidal effect (within 15-60 seconds), as well as an irritating, distracting, resolving infiltrate action.

Indications for use: alcohol solution of iodine is used as an antiseptic, distracting, irritating agent for inflammatory and other diseases of the skin and mucous membranes. With myositis, neuralgia, a distracting effect of the drug is manifested.

Contraindications: hypersensitivity to iodine.

Dosage and administration: alcohol solution of iodine is used externally.

Side effect : the drug with prolonged use can cause iodism (urticaria, runny nose, Quincke's edema, acne, lacrimation and salivation).

Interaction with other drugs:

alcohol iodine solution is incompatible with disinfectants containing mercury, oxidizing agents, alkalis.

Release form: alcohol iodine solution 5% is available in dark glass bottles with a volume of 10 ml.

◊ Solution for external use alcohol 1% transparent, red-brown in color, with a characteristic odor.

Excipients: ethanol 95%.

15 ml - vials.

pharmachologic effect

Elemental iodine has strong antimicrobial properties. Elemental iodine preparations are characterized by a pronounced local irritating effect on tissues, and in high concentrations - a cauterizing effect. Local action is due to the ability of elemental iodine to precipitate tissue proteins. Preparations that split off elemental iodine have a much less pronounced irritant effect, and iodides have local irritating properties only in very high concentrations.

The nature of the resorptive action of preparations of elemental iodine and iodides is the same. The most pronounced effect in the resorptive action of iodine preparations is on the function of the thyroid gland. With iodine deficiency, iodides contribute to the restoration of impaired synthesis of thyroid hormones. With normal iodine content in environment iodides inhibit the synthesis of thyroid hormones, the sensitivity of the thyroid gland to pituitary TSH decreases and its secretion by the pituitary gland is blocked. The effect of iodine preparations on metabolism is manifested by an increase in dissimilation processes. When they cause a slight decrease in the concentration of cholesterol and beta-lipoproteins in the blood; in addition, they increase the fibrinolytic and lipoproteinase activity of blood serum and slow down the rate of blood clotting.

Accumulating in syphilitic gums, iodine contributes to their softening and resorption. However, the accumulation of iodine in tuberculous foci leads to an increase in the inflammatory process in them. The excretion of iodine by the excretory glands is accompanied by irritation of the glandular tissue and increased secretion. This is due to the expectorant effect and stimulation of lactation (in small doses). However, in large doses, iodine preparations can cause lactation suppression.

Pharmacokinetics

Upon contact with the skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs and is selectively absorbed by the thyroid gland. It is excreted mainly by the kidneys, intestines, sweat and mammary glands.

Indications

For external use: infectious and inflammatory skin lesions, injuries, wounds, myalgia.

For local use: chronic tonsillitis, atrophic rhinitis, purulent, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of I-II degree.

For oral administration: prevention and treatment of atherosclerosis, tertiary.

Contraindications

Hypersensitivity to iodine. For oral administration - pulmonary tuberculosis, nephritis, nephrosis, adenomas (including the thyroid gland), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, childhood up to 5 years.

Dosage

When applied externally, iodine is used to treat damaged areas of the skin.

For oral administration, the dose is set individually, depending on the indications and the age of the patient.

Locally used for washing lacunae and supratonsillar spaces - 4-5 procedures at intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for instillation into the ear and washing - for 2-4 weeks; in surgical practice and in case of burns, gauze wipes applied to the affected surface are moistened as needed.

Side effects

For external use: rarely - skin irritation; with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, salivation, lacrimation, acne).

When taken orally: skin allergic reactions, tachycardia, nervousness, sleep disturbances, excessive sweating, diarrhea (in patients over 40 years of age).

One vial (10 ml) contains: active ingredient : iodine - 0.5 g, Excipients
One vial (800 ml) contains: active ingredient: iodine - 40 g, Excipients- potassium iodide, ethyl alcohol, purified water.
One vial (900 ml) contains: active ingredient: iodine - 45 g, Excipients- potassium iodide, ethyl alcohol, purified water.

Pharmacotherapeutic group

Antiseptic.
ATX code: D08AG03.

Pharmacological properties"type="checkbox">

Pharmacological properties

Pharmacodynamics
Antiseptic. The main active ingredient is molecular iodine, which has antimicrobial and antifungal properties. Iodine is able to oxidize and denature the proteins of microorganisms, causing their death. Molecular iodine preparations are characterized by a pronounced local irritating effect on tissues, and in high concentrations - a cauterizing effect. When absorbed and entering the blood, it can have a systemic effect, participating in the synthesis of thyroid hormones.
Pharmacokinetics
Upon contact with the skin, 30% is converted into iodides, and the rest remains in the form of elemental iodine. Partially absorbed from the skin surface. The absorbed part can enter tissues and organs, being selectively absorbed by the thyroid gland. Iodine is excreted by the kidneys (mainly), intestines, sweat and mammary glands.
Absorption of iodine through damaged skin and mucous membranes can be significant.

Indications for use

It is used externally as an antiseptic for infectious and inflammatory diseases of the skin, for the treatment of the surgical field, for the prevention of infection of small damage to the integrity of the skin.

Contraindications

Individual intolerance (including history of hypersensitivity).
Patients with impaired thyroid function (hyperthyroidism and adenoma) or receiving lithium therapy.
Skin treatment for furunculosis, acne, hemorrhagic diathesis, urticaria, diabetic trophic ulcers is not allowed.
Duhring's dermatitis herpetiformis.
Neonatal period.

Dosage and administration

When applied externally, a cotton swab is moistened with a solution of iodine, which is used to treat the affected areas of the skin. Do not use the drug for more than 10 days. When processing the surgical field, the skin is wiped twice with a sterile gauze swab dipped in a solution medicinal product. Total time processing - 4-6 min.

Side effect

Skin irritation, allergic reactions, including angioedema, urticaria, contact dermatitis, with prolonged use on extensive wound surfaces - "iodism" (lacrimation, hypersalivation, rhinorrhea, bronchorrhea, swelling of the mucous membranes).
May cause skin hemorrhages or purpura, fever, arthralgia, lymphadenopathy and eosinophilia.

Overdose

In case of an overdose, iodism, irritation and burns are possible.
When inhaling concentrated vapors - damage to the upper respiratory tract(burn, laringo- and bronchospasm); if concentrated solutions get inside - severe burns of the digestive tract; in case of ingestion - the development of hemolysis, hemoglobinuria; the lethal dose is about 3 g.
Treatment: gastric lavage with 0.5% sodium thiosulfate solution, intravenous administration sodium thiosulfate solution 30% - up to 300 ml. In case of a severe skin reaction to iodine, the drug should be removed immediately with 70% ethyl alcohol. It is also recommended to wash the skin with plenty of water for 15 minutes. In case of accidental swallowing, if the patient is conscious - milk inside every 15 minutes.
If the drug is not used to treat large open wounds or is used for no more than 10 days, clinically significant systemic absorption is unlikely. Systemic toxicity may result in shock, tachycardia, fever, metabolic acidosis, and kidney failure. Death can be caused by circulatory failure, epiglottis edema leading to asphyxia, aspiration pneumonia, or pulmonary edema.

Precautionary measures

It is not recommended to use the drug in children under two years of age due to an increased risk of hypothyroidism.
The undiluted drug should not be allowed to come into contact with the mucous membranes of the mouth, eyes, vagina and rectum.
It is not recommended for use in deep or puncture wounds, severe burns, as the use of the drug may cause excessive absorption of iodine and tissue irritation.
Do not use the drug for more than ten days!
It is not recommended to treat large areas of the skin with the drug.
The use of the drug may affect the results of thyroid function tests.

Pregnancy and lactation

Children

The use of the drug in newborns is contraindicated and the use of the drug in children under two years of age is not recommended due to the high probability of systemic absorption of iodine when applied topically.
Local application in children can lead to severe skin reactions to iodine, iodism, transient hypothyroidism.

antiseptic for animals

(Organization-developer: Vettorg LLC,

143180, Moscow region, Zvenigorod, Nakhabinskoe highway, 2)

I. GENERAL INFORMATION

Trade name of the medicinal product: Alcohol iodine solution 5% (Solutio Iodi spirituosa 5%).

International non-proprietary name: iodine.

Dosage form: solution for external use.

Alcoholic iodine solution 5% - a drug in the form of a solution, 100 ml contains 5 g of crystalline iodine as an active ingredient, potassium iodide, ethyl alcohol (ethanol) and purified water 1: 1 as auxiliary substances.

A solution of iodine alcohol 5% is clear liquid brown-brown color with a characteristic odor of iodine. Shelf life, subject to storage conditions in a tightly closed container of the manufacturer, is 3 years from the date of production. Do not use alcohol iodine solution 5% after the expiration date.

A 5% alcohol iodine solution is produced packaged in 10, 25, 30, 40, 50, 100 and 500 ml bottles and bottles made of dark (orange) glass of the appropriate capacity, sealed with polyethylene stoppers and closed with threaded plastic caps. Consumer packages, complete with instructions for use, are put into group (tare) packaging.

Alcoholic iodine solution 5% is stored in the manufacturer's packaging, separately from food and feed, in a dry place protected from direct sunlight at a temperature of 0 °C to 25 °C.

A solution of iodine alcohol 5% should be stored out of the reach of children.

The unused medicinal product is disposed of in accordance with the requirements of the legislation.

Vacation conditions: without a prescription from a veterinarian.

II. PHARMACOLOGICAL (BIOLOGICAL) PROPERTIES

Pharmacotherapeutic group: antiseptic for external use. Alcoholic iodine solution 5% has an antimicrobial, irritating, distracting effect, accelerates wound healing. When applied to the skin, active iodine is slowly and evenly released from the preparation, which oxidizes the amino acids of enzymes and transmembrane proteins of pathogenic microorganisms.

According to the degree of impact on the body, a 5% alcohol solution of iodine belongs to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76).

III. HOW TO USE

Alcoholic iodine solution 5% is prescribed as an antiseptic, hemostatic agent; for processing the surgical field, surgical sutures, places for parenteral administration medicinal substances(injections) and fingers of the surgeon; in the primary treatment of fresh wounds, for the treatment of infected wounds, for injuries, abrasions, cuts, furunculosis, abscesses and fistulas; as a distraction and irritant chronic inflammation joints, tendons, muscles.

A contraindication for the use of a 5% alcohol iodine solution is an individual hypersensitivity of the animal to iodine-containing drugs.

A solution of iodine alcohol 5% is used externally. The treatment of the skin surface is carried out once. Lubricate the affected areas of the skin along the edges of the wound with gauze or cotton swabs soaked in a 5% alcohol iodine solution, without applying to the wound. When processing the surgical field, the skin is wiped twice with a sterile gauze swab dipped in iodine solution. For a distracting effect, a 5% alcohol solution of iodine is applied to the skin in the form of a grid.

When using a solution of iodine alcohol 5% according to the instructions, symptoms of an overdose in animals are not detected. It is advisable not to re-treat during the day, since an excess of active iodine can cause a chemical burn.

Features of the action of a solution of iodine alcohol 5% during the first application and cancellation have not been established.

Pregnant animals, newborns and young animals should use iodine solution with caution to avoid chemical burns.

Frequent use of a 5% iodine solution is not provided. An increase in the intervals between treatments does not affect the effectiveness of treatment.

When used correctly side effects are usually not observed. With repeated and frequent lubrication with an iodine solution during the day, as well as with prolonged use on large surfaces, inflammatory reactions and skin burns are possible, as well as iodism phenomena, that is, iodine poisoning (urticaria, rhinitis, salivation, lacrimation, swelling of the eyelids).

Alcoholic iodine solution 5% is pharmaceutically incompatible with essential oils, ammonia solutions. When combined with a yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible.

Products of animal origin obtained from animals after treatment with a 5% alcohol iodine solution are used without restrictions.

IV. PERSONAL PREVENTION MEASURES

When working with a solution of iodine alcohol 5%, you should observe general rules personal hygiene and safety measures provided for when working with medicines.

In case of accidental contact of a solution of iodine alcohol 5% with the mucous membrane of the eyes, immediately rinse the eyes with plenty of water. In case of allergic reactions or in case of accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for using the drug and a label with you).