Nazivin adult instructions for use. Nazivin drops - instructions for use

Nazivin is a drops or spray with a vasoconstrictive effect for local application, alpha2-agonist. Reduces swelling of the nasal mucosa and the amount of discharge. The active substance is Oxymetazoline.

The drug reduces the amount of discharge from the nose, restores nasal breathing, relieves swelling of the inflamed mucous layers of the nose, and also prevents the development of bacterial complications (sinusitis, sinusitis and otitis media).

Therapeutic doses do not have a systemic effect.

Nazivin begins to act in ~ 10 minutes after application, the duration of action is up to 12 hours.

Release form:

Drops in vials with pipette caps 0.05%, 0.025% and 0.01%.
Spray 0.05% in a 10 ml spray bottle.

Indications for use

What helps spray Nazivin? According to the instructions, the drug is prescribed in the following cases:

In acute diseases of the respiratory tract, which are accompanied by rhinitis (runny nose);
allergic rhinitis;
With vasomotor-allergic rhinosinusopathy (vasomotor rhinitis - a disease in which a violation of nasal breathing is associated with swelling of the tissues of the nasal cavity);
If it is necessary to restore drainage in case of sinusitis (inflammation of the mucous membrane of the paranasal sinuses), salpingo-otitis (inflammation of the mucous membrane of the Eustachian tube and tympanic cavity), otitis media;
To relieve swelling of the tissues of the nasal cavity before carrying out diagnostic procedures.

Instructions for use Nazivin, dosage spray for adults

The drug in any form of release is intended for intranasal administration (into the nasal passages).

Adults and children over 6 years of age are prescribed nasal drops of 0.05%. Standard dosages, according to the instructions for use of Nazivin (in each nasal passage):

Drops - from 1 to 2 drops \ from 2 to 3 times a day;
Spray - 1 injection \ 2 to 3 times a day.

Duration of application - from 5 to 7 days.

Nazivin Sensitive

Dosed spray Nazivin Sensitiv 22.5 mcg per dose is prescribed for children and adolescents from 6 to 18 years of age. It is recommended to do 1 injection of the solution into each nasal passage 2 or 3 times a day.

Duration of application - up to 7 days.

special instructions

During pregnancy and lactation, it should be used only in dosages prescribed by a doctor.

Prolonged use leads to a weakening of the action. Abuse of vasoconstrictors can cause mucosal atrophy, reactive hyperemia with drug-induced rhinitis, damage to the mucosal epithelium and suppression of its activity.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Nazivin spray:

Dryness of the nasal mucosa;
Feeling of burning or tingling in the nose after instillation of the drug;
Irritation of the nasal mucosa, severe sneezing;
Itching in the nose;
Hyperemia and swelling of the nasal cavity with individual intolerance.

As a rule, all symptoms are not dangerous for a person and disappear on their own after discontinuation of the drug.

Contraindications

Nazivin is contraindicated in the following cases:

Glaucoma;
Hypersensitivity;
atrophic rhinitis;
Age up to 6 years (for drops \ spray 0.05%).

It is prescribed with caution when using MAO inhibitors, increased intraocular pressure, severe forms of arterial hypertension and angina pectoris, thyrotoxicosis.

The use of the drug during pregnancy and lactation is possible only after a thorough assessment of the ratio of benefit to the mother and risk to the fetus or infant. It is unacceptable to exceed the recommended dose.

Overdose

Overdose symptoms - pupillary constriction, vomiting or nausea, fever, tachycardia, cardiac depression, arterial hypertension, collapse.

With the development of symptoms, stop using the drug and consult a doctor immediately.

Instructions for use:

Nazivin is a synthetic drug used topically in ENT practice for the treatment of acute respiratory diseases accompanied by rhinitis.

pharmachologic effect

The active substance of Nazivin drops produces a vasoconstrictive effect.

The drug reduces swelling of the inflamed nasal mucosa, restores nasal breathing, reduces the amount of discharge and prevents the development of bacterial complications, including sinusitis, sinusitis and otitis media. When used in therapeutic doses, the drug does not irritate the mucous membranes and does not have a systemic effect.

Nazivin begins to act a few minutes after application, the duration of action is up to 12 hours. Drops are widely used in pediatrics, including newborns, but Nazivin is used during pregnancy only under strict indications.

Release form

Nazivin is produced in the form of transparent nasal drops. 1 ml of drops contains 100 mcg (in dark 5 ml vials with a pipette cap), 250 mcg or 500 mcg (in dark 10 ml vials with a pipette cap) of oxymetazoline hydrochloride. Excipients - disodium edetate dihydrate, benzalkonium chloride 50% solution, sodium hydrogen phosphate dihydrate, sodium hydroxide 1M solution, sodium dihydrogen phosphate dihydrate and purified water.

Nazivin is also produced in the form of a nasal spray, 1 ml of the spray solution contains 500 μg of oxymetazoline hydrochloride, in a 10 ml polyethylene bottle with a spray.

Indications for Nazivin's use

According to the instructions, Nazivin is used to treat:

Acute respiratory diseases accompanied by rhinitis;
Vasomotor rhinitis;
allergic rhinitis.

Nazivin drops are also used:

To restore drainage with eustachitis, inflammation of the paranasal sinuses of the nasal cavity and otitis media;
To eliminate edema before diagnosis in the nasal passages.

Contraindications

Nazivin is contraindicated for:

atrophic rhinitis;
Hypersensitivity to the components of the drug;
Angle-closure glaucoma.

Nazivin for infants and children under 6 years of age is used in the dosage form of a 0.05% solution.

During lactation and pregnancy, Nazivin is used only under strict indications.

The drug is prescribed with caution at the same time:

With MAO inhibitors and other drugs that increase arterial pressure;
With increased intraocular pressure;
At diabetes and thyrotoxicosis;
In severe forms of cardiovascular disease, including arterial hypertension and angina pectoris.

Application instruction of Nazivin

Depending on age, different dosage forms drug. For all age groups, Nazivin drops are used 2-3 times a day, the recommended course is 3-5 days.

Nazivin for infants up to a year is used in the form of a 0.01% solution:

Newborns up to a month are injected one drop into each nostril;
From a month to a year - 1-2 drops of Nazivin.

For the accuracy of the dosage of Nazivin for infants, a bottle with a 0.01% solution has a degree pipette.

For children 1-6 years old, children's Nazivin 0.25% is used, 1-2 drops each.

It is also effective, depending on the age, to apply children's Nazivin on cotton turundas and clean the nasal passages.

Adults and children over 6 years of age are prescribed 1-2 drops of a 0.05% solution.

When using Navizin during pregnancy, the recommended dose should not be exceeded.

Side effects

According to the instructions, Nazivin is usually well tolerated. V rare cases the drug may cause:

sneezing, dryness or burning sensation of the nasal mucosa;
insomnia, restlessness, tiredness or headache;
Nausea.

With prolonged use without interruption, Nazivin drops according to the instructions can lead to recurrent swelling of the mucous membranes of the nasal cavity, atrophy or tachyphylaxis.

It should be borne in mind that the simultaneous use of Nazivin with other vasoconstrictor drugs increases the risk of side effects.

In case of an overdose, Nazivin according to the instructions can cause:

Increase in body temperature;
Constriction of the pupils;
tachycardia;
Collapse;
Pulmonary edema;
Nausea and vomiting;
Cyanosis;
Inhibition of cardiac activity;
arrhythmia;
arterial hypertension;
Respiratory disorders.

Also, an overdose can cause mental disorders, bradycardia, respiratory arrest, arterial hypotension.

Storage conditions

Drops Nazivin is an over-the-counter drug. Shelf life - 3 years.

The most common causes of a runny nose are various viruses, allergens or pathogenic bacteria. They provoke inflammation of the mucous membrane and its swelling, copious discharge from the nose, interfere with breathing through the nose, eating and sleeping peacefully at night.

To combat such symptoms in children, vasoconstrictor drugs are often used. One of the medicines of this group is Nazivin. In what forms is it produced, how does it act on children's body what dose is recommended childhood and how to bury Nazivin in the nose of a child older than a year?

Release form and composition

The drug is produced in the form of clear liquid, which has no color or has a slight yellow tint. The main ingredient of such a solution is oxymetazoline in the form of hydrochloride. The concentration of this substance is different, as is the packaging of the medicine. Nazivin in pharmacies is presented:

Drops in the nose. They are available in glass bottles equipped with special pipettes on the cap. The concentration of such a drug can be 0.01%, 0.025% and 0.05%. The drug with the lowest dosage is intended for children under one year old and is represented by a 5 ml bottle. Drops with a concentration of 0.025% and 0.05% are available in 10 ml in one bottle. In addition to oxymetazoline, they contain disodium edetate, sodium dihydrophosphate and sodium hydrogen phosphate, as well as water, sodium hydroxide and benzalkonium chloride.
nasal spray. It is produced in plastic bottles that have a sprayer. Inside one bottle is 10 ml of solution, and the concentration of oxymetazoline in it is 0.05%, which corresponds to a dosage of 500 μg / 1 ml. Additional components of the drug are citric acid, glycerol, benzalkonium chloride, purified water and sodium citrate.

In addition, Nazivin Sensitive can be seen in the assortment of pharmacies. Main component such a medicine (oxymetazoline). Indications, possible negative effects and contraindications completely coincide with the usual Nazivin. First of all, the drug marked "sensitive" is intended for children prone to allergies, since it does not include benzalkonium chloride and rarely causes an allergic reaction.

One of the forms of Nazivin Sensitiv are drops that include 0.01% of the active ingredient and are used in the treatment of infants. For children older than a year, the medication is produced in the form of a dosed spray:

With the content of the active ingredient in one dose of 11.25 mcg, which corresponds to a concentration of 250 mcg / 1 ml.
With the content of oxymetazoline in 1 dose in the amount of 22.5 mcg, that is, with a concentration of 500 mcg / 1 ml.

Each of these drugs is available in 10 ml vials and contains approximately 220 doses of medication. The bottles are made of plastic and equipped with a special dosing device.

Operating principle

The active compound of Nazivin affects alpha-2 adrenoreceptors, as a result of which there is a narrowing of small vessels that are in the nasal passages. Medication use:

Reduces swelling and hyperemia of the mucous membrane of the nasopharynx.
Reduces nasal discharge.
Helps restore breathing through the nose.
Additionally, it affects the paranasal sinuses, as well as the middle ear, preventing the complications of a cold in the form of sinusitis or otitis media.
Renders therapeutic effect only at the point of processing.
Does not provoke redness and irritation of the mucous membrane inside the nasal passages.

The drug begins to act literally in the first minutes after it enters the nose, and the vasoconstrictor effect after treatment with the solution lasts up to 12 hours.

Indications

In childhood, Nazivin is in demand:

In the treatment of SARS, if the disease is manifested by a runny nose.
In the treatment of allergic rhinitis.
In the treatment of rhinitis, which is called vasomotor.
In combination with other drugs for eustachitis, adenoids, otitis or sinusitis.
Before performing any diagnostic manipulations in the nasal passages.

What forms are used in children older than a year?

For infants, 0.01% drops are released, but for older children, the amount of active compound in such Nazivin will be insufficient. At the age of one to six, drops are prescribed, in which there is 0.025% oxymetazoline. For the treatment of children over 6 years of age, a 0.05% solution is prescribed in any form.

As for Nazivin Sensitive, in children older than a year, only a spray is used, one dose of which contains 11.25 μg of the active ingredient. A more concentrated agent containing 22.5 micrograms of oxymetazoline in each dose is used from the age of six.

What to choose?

When choosing the most optimal form of medicine for a child, first of all, the concentration of the drug is taken into account, after which it is determined with the packaging. Note that it is very convenient to use both types of Nazivin - the drops are easily dosed and fall directly into the nose of the kids thanks to the curved shape of the pipette built into the lid, and the spray is sprayed with a light touch throughout the mucous membrane in the right dose. However, in practice, the spray form seems more suitable for most mothers, since you do not need to lie down to administer the drug, and the risk of overdose with such a remedy is minimal.

Contraindications

Treatment with Nazivin is prohibited:

In case of hypersensitivity to oxymetazoline or any other ingredient of the solution.
With angle-closure glaucoma.
With rhinitis occurring in an atrophic form.

If the child has any diseases of the cardiovascular system, diabetes mellitus is found, or thyrotoxicosis is present, Nazivin should be dripped or injected with caution.

Side effects

Side effects include:

Sometimes, after the introduction of Nazivin into the nose, such negative local symptoms occur as a feeling of dryness, sneezing, a slight burning sensation, and discomfort in the nasal passages.
After the action ceases, reactive hyperemia is often observed and the child begins to complain of nasal congestion.
In some children, the drug provokes restless behavior, nausea, sleep disturbances, fatigue, headaches.
Prolonged use of the spray / drops is addictive and drug-induced rhinitis. In addition, very long treatment can cause atrophic changes in the nasal mucosa.

Instructions for use

Before injecting / dripping Nazivin, you should clean the nasal passages, removing excess secretions from them. To do this, it is advised to use a syringe or an aspirator, because the use of cotton swabs can be dangerous, especially at an early age. Before applying the drops, a small patient is placed on a flat surface and the head is slightly tilted back. The older child is asked to sit up and tilt their head slightly back. The medication is first dripped into one nasal passage so that the drug gets on the side wall, and then the same steps are repeated for the second nostril.

If a spray is used, the child should be warned to hold their breath. After completing the procedure, the excess solution that has flowed out of the nose is wiped with a cotton pad or napkin.

For patients from 1 to 6 years old, the solution is prescribed in such single doses:

One or two drops of 0.025% Nazivin in the form of nasal drops.
One injection of Sensitiv spray containing 11.25 mcg of oxymetazoline in each dose.

If the child is already 6 years old, then use the following single dosages:

One drop of Nazivin 0.05%, produced in nasal drops (sometimes 2 drops at once).
1 injection of 0.05% Nazivin spray.
One injection of the drug Sensitiv containing 22.5 μg of the active compound in each dose.

The drug is alternately injected in the indicated doses, first into one and then into the second nasal passage. The frequency of use is twice a day, and if necessary, the medicine is puffed or dripped three times a day. The duration of treatment with a solution at any age is 3-5 days. If during this period the medication does not help, you should not continue treatment. In such a situation, it is best to consult a doctor and, together with him, choose another therapy.

Overdose

Due to the exceeded dose of Nazivin, vomiting, constriction of the pupils, increased heart rate, respiratory failure, fever, arrhythmia and other symptoms appear. If the overdose is severe, pulmonary edema, mental disorders and even coma may occur. Having discovered poisoning, after washing the stomach, you must immediately call ambulance.

Interaction with other drugs

Like many other vasoconstrictor drugs, Nazivin cannot be used with MAO blockers or tricyclic antidepressants. Also, you should not inject any other vasoconstrictors (for example, Otrivin or Xilen) into the nasal passages along with Nazivin, because this will increase side effects from drops or spray.

Terms of sale

All forms of Nazivin are classified as over-the-counter drugs, so you can easily buy medicine in most pharmacies. The price of the drug depends on its form and concentration, for example, Nazivin 0.05% spray costs an average of 140 rubles, and for 10 ml of 0.025% drops you need to pay from 130 to 150 rubles. Sensitive preparations are somewhat more expensive - 160-180 rubles per bottle.

Storage conditions and shelf life

It is recommended to keep Nazivin and Nazivin Sensitive at home at temperatures up to 25 degrees Celsius in a place where the medication will be securely hidden from small children. The shelf life of all forms of the drug is 3 years. If it has expired, it is unacceptable to drip or inject the solution into the child's nose. The date after which the medicine is no longer used is marked on the packaging of the spray or drops and does not depend on the opening time.

In 1 ml drops oxymetazoline hydrochloride 500mcg, 250mcg or 100mcg. Solution benzalkonium chloride, sodium dihydrophosphate dihydrate, EDTA, sodium hydroxide, water, sodium hydrogen phosphate dihydrate - as excipients.

Spray composition: in 1 ml oxymetazoline hydrochloride 500 mcg. A solution of benzalkonium chloride, sodium dihydrogen phosphate dihydrate, EDTA, sodium hydroxide, water, sodium hydrogen phosphate dihydrate - as excipients.

Release form

Drops in vials with pipette caps 0.05%, 0.025% and 0.01%.

Spray 0.05% in a 10 ml spray bottle.

pharmachologic effect

Vasoconstrictor.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

vasoconstrictor drug, alpha2-agonist. Reduces swelling of the mucosa when applied topically and the amount of discharge. Eliminating swelling of the mucous membranes, restores breathing and aeration of the paranasal sinuses and middle ear. The use of the drug prevents the development sinusitis, sinusitis, otitis media.

At therapeutic concentrations does not cause hyperemia and does not irritate mucous membranes. It begins to act in 10 minutes and the effect lasts for 12 hours.

Pharmacokinetics

When applied topically, it does not have a systemic effect. The half-life is about 35 hours. 2.1% is excreted in the urine, 1.1% in the feces.

Indications for use

Respiratory diseases associated rhinitis;
eustachitis;
sinusitis;
allergic rhinitis ;
diagnostic procedures in the nasal passages;
otitis media;
vasomotor rhinitis.

Contraindications

glaucoma;
hypersensitivity;
atrophic rhinitis;
age up to 6 years (for the drug 0.05%).

Prescribed with caution when using MAO inhibitors, increased intraocular pressure, severe forms arterial hypertension and angina pectoris, during pregnancy, thyrotoxicosis.

Side effects

Everything side effects rarely occur:

sneeze;
dryness and burning of the nasal mucosa;
reactive hyperemia after the end of treatment, manifested by nasal congestion (with an overdose);
insomnia;
anxiety;
headache;
nausea;
tachycardia and arterial hypertension(with an overdose);
atrophy of the mucous membranes (with an overdose).

Application instruction of Nazivin (Way and dosage)

Spray Nazivin, instructions for use

Spray 0.05% is prescribed for adults and children from 6 years of age. Recommended for 1 injection into the nasal passages 2-3 times a day. The recommended dose can be used for up to 7 days. If symptoms worsen within 3 days, you should consult a doctor.

Drops Nazivin, instructions for use

Adults and children from 6 years of age are prescribed 0.05% drops, 1-2 drops 2-3 times a day. Children from 1 to 6 years old - 0.025% drops 1-2 drops 2-3 times. Children under 1 year of age are prescribed 0.01% drug: for newborns, 1 drop 2-3 times. A bottle of 0.01% of the drug has a graduated pipette, on which the number of drops is marked (1, 2, etc.).

It is possible to inject the drug into the nose in another way: the required number of drops is applied to a cotton turunda and the nasal cavity is wiped with it. The duration of the drug is 3-4 days.

Overdose

Overdose appears constriction of the pupils, vomiting, nausea, fever, tachycardia, cardiac depression, arterial hypertension, collapse. There may be mental disorders. Treatment consists in washing the stomach and taking sorbents.

Interaction

With simultaneous use with antidepressants and MAO blockers, an increase in blood pressure is noted. With the simultaneous appointment of other vasoconstrictor drugs, the risk of adverse reactions increases.

Terms of sale

Storage conditions

Storage temperature up to 25°C.

Best before date

Nazivin during pregnancy

Nazivin at pregnancy it is possible to use only after assessing the benefits to the pregnant woman and the risk to the fetus. It is unacceptable to exceed the dose during this period.

Analogues Coincidence in the ATX code of the 4th level:

Drugs with the same active ingredient: Nazol, Nazol Advance, Sanorinchik, Knoxprey, Afrin, Nesopin, Fazin. Preparations analogues that have a similar effect: Galazolin, Xylometazoline, For the nose, Xymelin.

Reviews about Nazivin

Vasoconstrictor drops Nazivin, like other drops, should be considered as an "ambulance" and used only for 3-5 days of severe nasal congestion. With prolonged use, atrophy of the mucosa is possible. It should be noted that Nazivin, when used in the recommended dosage regimen, does not cause significant damage to the mucosa, is not addictive even with prolonged use, and its therapeutic efficacy, compared with others vasoconstrictor drops, achieved at low concentrations. Therefore the form oxymetazoline in the form of a 0.01% solution is safe and effective for treatment rhinitis even in newborns and infants.

It is known that this drug also has antiviral and anti-inflammatory effects. This explains its high efficiency in rhinitis viral etiology. This drug is the only anticongestant, which is approved in Russia for use in newborns. Studies have shown its high efficiency. This is evidenced by reviews of Nazivin:

“... I use Nazivin 0.01% nasal drops for my 2-year-old child. They act for a long time, so I drip 2 times a day, but not for a long time ”;
“... The child often has a runny nose and we are saved only by these drops - 2 days of treatment are enough and the congestion disappears”;
“... Most of all I like these drops. We use it with the whole family, but the children are less concentrated”;
"... It is enough to drip for 1-1.5 days, and then we switch to therapeutic drops (such as Pinosol), or simply bury herbal decoctions and treat the runny nose to the end."

Spray Nazivin is convenient for use in adults and seems to some to be more effective than drops. This is true: aerosol forms are more evenly distributed over the mucosa, which creates a pronounced therapeutic effect. In addition, the spray does not roll into the nasopharynx, as is the case when using drops.

Nazivin's price, where to buy

You can buy the drug at any pharmacy. The price of Nazivin 0.05% spray ranges from 221 rubles. up to 248 rubles, the cost of Nazivin Sensitiv spray is 231-352 rubles.

Internet pharmacies in RussiaRussia
Internet pharmacies of UkraineUkraine
Internet pharmacies of KazakhstanKazakhstan

WER.RU

Nazivin drops 0.01% 5 ml for childrenMerck & Co

Nazivin Sensitive nasal spray 22.5 mcg/dose 10 ml 220 doses

Nazivin Sensitive nasal spray 11.25 mcg/dose 10 ml 220 doses

Nazivin spray 0.05% 10 mlMerck & Co

Nazivin drops 0.05% 10 mlMerck & Co

ZdravZone

Nazivin nasal drops for children under 1 year old 0.01% 5ml Merck KGaA

Nazivin nasal drops for children 1-6 years old 0.025% 10ml Merck KGaA

Nazivin nasal spray 0.05% 10ml Merck KGaA

Nazivin Sensitive nasal spray for children 1-6 years old 11.25mcg/dose 10mlMerck KGaA

Nazivin Sensitive nasal spray 22.5mcg/dose 10mlMerck KGaA

Pharmacy IFK

NaziwinMerck, Germany

Naziwin SensitiveMerck, Germany

Pharmacy24

Nazivin nasal aerosol 0.05% 10mlNycomed (Austria)

NazivinMerck KGaA (Germany)

PaniApteka

Nazivin nasal drops 0.01% 5mlNycomed

Nazivin sensitive nose drops 0.01% 5mlMerc KgaA

Nazivin spray 0.05% 10mlNycomed

BIOSPHERE

Nazivin Sensitiv 11.25 mcg/dose 10 ml spray naz.doz. Ursapharm Arzneimittel (Germany)

Nazivin Sensitiv 22.5 mcg/dose 10 ml spray naz.doz.Ursapharm Arzneimittel (Germany)

Nazivin Sensitiv 0.01% 5 ml drops called Ursapharm Arzneimittel (Germany)

Nazivin 0.025% 10 ml drops named Merck KGaA (Germany)

Nazivin 0.05% 10 ml spray called Merck KGaA (Germany)

NOTE! Information about medicines on the site is a general reference, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medicines in the course of treatment. Before use medicinal product Nazivin be sure to consult with your doctor.

Registration number:

Name of the drug: NAZIVIN®

International non-proprietary name:

Oxymetazoline

Dosage form:

Nasal drops

Compound
1 ml of the drug contains:
Active substance:
Nazivin 0.01% - Oxymetazoline hydrochloride 0.1 mg
Nazivin 0.025% - Oxymetazoline hydrochloride 0.25 mg
Nazivin 0.05% - Oxymetazoline hydrochloride 0.5 mg
Excipients: benzalkonium chloride 50% solution, disodium edetate dihydrate, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, sodium hydroxide 1 M solution, purified water.

Description: Almost clear, colorless to slightly yellowish solution.

Pharmacotherapeutic group:

Alpha

adrenomimetic agent.

ATC Code: .

Pharmacological properties

Pharmacodynamics. Nazivin® (oxymetazoline) has a vasoconstrictive effect. When applied topically to the inflamed nasal mucosa, it reduces swelling and discharge from the nose. Restores nasal breathing.
Elimination of mucosal edema helps to restore aeration of the paranasal sinuses, the middle ear cavity, which prevents the development of bacterial complications (sinusitis, sinusitis, otitis media).
When applied locally intranasally in therapeutic concentrations, it does not irritate the mucous membrane, does not cause hyperemia.
With local intranasal application, the drug does not have a systemic effect. The drug begins to act quickly (within a few minutes). The duration of action of Nazivin is up to 12 hours.

Indications

treatment of acute respiratory diseases accompanied by a runny nose; allergic rhinitis; vasomotor rhinitis; to restore drainage in case of inflammation of the paranasal sinuses of the nasal cavity, eustachitis, otitis media; to eliminate edema before diagnostic manipulations in the nasal passages. Contraindications
atrophic rhinitis; angle-closure glaucoma; hypersensitivity to the components of the drug.
You should adhere to the recommended concentrations of the drug intended for different age categories (see methods of application). Carefully
In patients taking monoamine oxidase inhibitors and other drugs that increase blood pressure for up to 10 days after their use; with increased intraocular pressure, during pregnancy and lactation, with severe forms of cardiovascular diseases (hypertension, angina pectoris); with thyrotoxicosis and diabetes mellitus. Pregnancy and lactation
Dosage and administration
Nazivin® 0.01%, 0.025% and 0.05% drops are intended for nasal use.
Adults and children over 6 years of age: apply Nazivin® 0.05% drops 1-2 drops in each nasal passage 2-3 times a day.
Children from 1 to 6 years of age: apply Nazivin® 0.025% drops 1-2 drops in each nasal passage 2-3 times a day.
Children under 1 year old: children under the age of 4 weeks are prescribed 1 drop of Nazivin® 0.01% in each nasal passage 2-3 times a day. From the 5th week of life and up to 1 year - 1-2 drops in each nasal passage 2-3 times a day.
To ensure dosing accuracy, the bottle of Nazivin® 0.01% drops has a graduated pipette with marks for the number of drops. For example, if 1 drop is assigned, then the pipette should be filled with the solution to the 1 mark.
The effectiveness of the following procedure has also been proven: depending on age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages. Nazivin® 0.01%, 0.025% and 0.05% drops should be used for 3-5 days. Doses higher than those recommended can only be used under medical supervision. special instructions
Interaction with other drugs
With the simultaneous appointment of MAO blockers and tricyclic antidepressants, an increase in blood pressure.
Side effect
Sometimes: burning or dryness of the nasal membranes, sneezing. In rare cases: after the effect of the use of Nazivin passes, a strong feeling of "congestion" of the nose (reactive hyperemia). Multiple overdose with local nasal use sometimes leads to systemic sympathomimetic effects such as increased heart rate (tachycardia) and increased blood pressure. In very rare cases, anxiety, insomnia, fatigue, headaches and nausea have been observed. Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent swelling of the nasal mucosa (drug rhinitis). Overdose
After a significant overdose or accidental ingestion, the following symptoms may appear: pupillary constriction, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, collapse, cardiac depression, arterial hypertension, pulmonary edema, respiratory disorders. In addition, mental disorders may appear, as well as depression of the functions of the central nervous system, accompanied by drowsiness, a decrease in body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development coma. In case of overdose associated with oral administration, gastric lavage, activated charcoal are prescribed. Influence on the ability to drive vehicles and equipment:
After prolonged use or intake of drugs for the common cold containing oxymetazoline, in dosages exceeding the recommended ones, a general effect on cardiovascular system and central nervous system. In these cases, the ability to manage vehicle or equipment may decrease. Release form.
Nasal drops 0.01%; 0.025% and 0.05%.
For Nazivin® 0.01%: 5 ml in a dark glass bottle with a pipette cap.
For Nazivin® 0.025% and 0.05%: 10 ml in a dark glass bottle with a pipette cap.
1 vial with instructions for use is placed in a cardboard box. Storage
Store at a temperature not exceeding 25 °C.
Keep out of the reach of children. Best before date
3 years.
Do not use after the expiration date.

Conditions for dispensing from pharmacies:

without recipe.

Manufacturer:

Merck KGaA, Germany
Frankfurterstr. 250, 64293 Darmstadt
Frankfurterstr., 250.64293 Darmstadt Address of the Nycomed representative office in Russia/CIS:
119049 Moscow, st. Shabolovka, 10, building 2.

Nazivin - famous pharmaceutical agent widely used for medical purposes in ENT diseases and colds.

The main active ingredient of the drug is oxymetazoline. This substance stimulates the work of α2-adrenergic receptors, as a result of which more hormones of norepinephrine and adrenaline are released at the site of exposure, which reduce swelling, constricting blood vessels, reducing the volume of blood in them. Thanks to this effect, nasal breathing is facilitated, air enters the sinuses, and the amount of mucus secreted decreases.

For these purposes, the drug is used not only for adults, it is also widespread and Nazivin for children, which has various forms of release, such as Nazivin Baby, Nazivin Sensitive, etc.

Clinical and pharmacological group

Vasoconstrictor drug for local use in ENT practice.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does Nazivin cost? The average price in pharmacies is at the level of 140 rubles.

Release form and composition

The active substance of the drug is oxymetazoline.

Children's Nizivin is produced in a solution of 0.025% and 0.01%. The basis of the solution is water. It contains additional components: disodium edetate, benzalkonium chloride 50%, sodium hydrogen phosphate, sodium hydroxide 1 ml solution. Produced in dark glass bottles of 5 ml or 10 ml with a pipette in the lid.

When used for children under one year old, the drops are diluted with special water used for injections in a ratio of 1: 1 or distilled in the same proportion. Used for instillation into the nose.

Pharmacological effect

When Nazivin gets on the inflamed nasal mucosa, its swelling and the volume of secreted mucus decrease. This is due to the effect of the drug on adrenaline receptors, which are located in the blood vessels (in muscle fibers). The receptors are reduced, and there is a decrease in vascular permeability due to their narrowing.

The use of Nazivin improves nasal breathing, eliminates swelling of the mucous membranes. And also the drug reduces the risk of complications in the paranasal sinuses and middle ear (sinusitis, sinusitis and otitis media). After the drug enters the blood due to absorption in the mucous membranes, there is a narrowing of the vessels (arteries) in the organs and tissues, and the heart rate also increases. As a result, blood pressure rises and the heart rate changes.

When using Nazivin on the mucous membranes in the recommended doses, it does not fall into circulatory system and does not cause a systemic effect on the body. Nazivin does not irritate the nasal mucosa and does not cause overflow of blood vessels (hyperemia).

The maximum effect of the drug is achieved 15 minutes after application. The action persists for 8 hours.

Indications for use

What helps? Nazivin is used for:

ARI if there is a runny nose;
sinusitis, eustachitis, otitis media and inflammation of the paranasal sinuses to facilitate the outflow of mucus;
preparation of nasal passages for diagnostic procedures;
allergic and vasomotor rhinitis.

Contraindications

When using the product, it is important to follow the rules given in the instructions, then the substance can be instilled even for babies up to 1 year old. However, the drug has a number of contraindications. In some cases, its use will have to be abandoned:

children's age up to 6 years (drops and nasal spray 0.05%);
atrophic rhinitis;
angle-closure glaucoma;
hypersensitivity to the components of the drug.

With caution should be prescribed with the simultaneous use of MAO inhibitors and other drugs that increase blood pressure, as well as in the period up to 10 days after the abolition of these medicines; with increased intraocular pressure; during pregnancy and lactation; in severe forms of cardiovascular diseases (arterial hypertension, angina pectoris); with thyrotoxicosis and diabetes mellitus.

Use during pregnancy and lactation

When used during pregnancy or breastfeeding do not exceed the recommended dosage. The drug should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus.

Dosage and method of application

The instructions for use indicate that Nazivin drops are intended for intranasal use.

Children under the age of 1 year are prescribed drops of 0.01%.

Newborns (children under the age of 4 weeks) are administered 1 drop in each nostril 2-3 times / day.
Children aged 1 month to 1 year are prescribed 1-2 drops in each nostril 2-3 times / day.
Children aged 1 to 6 years should be prescribed drops of 0.025%, 1-2 drops in each nostril 2-3 times / day.
Adults and children over 6 years of age should be prescribed drops of 0.05%, 1-2 drops in each nostril 2-3 times / day.

To ensure dosage accuracy, the 0.01% drop bottle has a graduated pipette with marks for the number of drops. If 1 drop is prescribed, then the pipette should be filled with a solution to the 1 mark.

The effectiveness of the following procedure has also been proven: depending on the age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages.

Nazivin should be used within 3-5 days. Doses higher than those recommended are prescribed at the discretion of the physician.

Side effects

Side effects when using Nazivin occur infrequently. Burning, dryness of the nasal mucosa and sneezing are possible. Rarely, reactive hyperemia occurs - severe congestion nose with the weakening of the drug.

Overdose

An overdose of oxymetazoline occurs when a large amount of the substance enters the gastrointestinal tract and bloodstream. This may happen when Small child has access to drops and accidentally drinks them. Parents are strongly advised to keep any medication out of the reach of the child.

With topical application of drops according to the instructions, an overdose is excluded. But at the same time, there is a risk when drugs with a high concentration of the active ingredient are used to treat young children.

Symptoms of severe overdose:

temperature rise to subfebrile;
respiratory failure due to edema;
mental and nervous disorders;
increase in blood pressure;
arrhythmia, difficult breathing;
constriction of the pupils;
drowsiness and reduced activity.

When a life-threatening amount of a substance enters the bloodstream, a sharp decrease in body temperature, respiratory depression, and a decrease in the frequency of heart contractions are observed. This can result in respiratory arrest and the development of a coma.

Treatment: taking activated charcoal and gastric lavage of the child.

special instructions

Long-term use and overdose of the drug should be avoided, especially in children.

After prolonged use of drugs containing oxymetazoline, in doses exceeding those recommended, a general effect on the cardiovascular system and central nervous system cannot be excluded; in these cases, the ability to drive a vehicle or equipment may be reduced.

drug interaction

With the simultaneous use of Nazivin with MAO blockers or tricyclic antidepressants, an increase in blood pressure is observed.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

In this article, you can read the instructions for using the drug Nazivin. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Nazivin in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Nazivin's analogues in the presence of existing structural analogues. Use for the treatment of rhinitis with colds and allergies in adults, children (including infants - babies up to a year and newborns), as well as during pregnancy and lactation. The composition of the drug.

Nazivin- vasoconstrictor drug for topical use, alpha2-adrenergic agonist.

When applied topically to the inflamed mucous membranes of the nose, it reduces their swelling and the amount of discharge. Restores nasal breathing. Eliminating swelling of the mucous membranes, the drug helps to restore aeration of the paranasal sinuses, the middle ear cavity and prevents the development of bacterial complications (sinusitis, sinusitis, otitis media).

With local intranasal application in therapeutic concentrations, Nazivin does not have a systemic effect, does not irritate the mucous membranes and does not cause hyperemia.

The drug begins to act within a few minutes. Duration of action up to 12 hours.

Compound

Oxymetazoline hydrochloride + excipients.

Indications

treatment of acute respiratory diseases accompanied by rhinitis;
allergic rhinitis;
vasomotor rhinitis;
restoration of drainage in case of inflammation of the paranasal sinuses of the nasal cavity, eustachitis, otitis media;
elimination of edema before diagnostic manipulations in the nasal passages.

Release forms

Nose drops 0.01%, 0.025%, 0.05%.

Nasal spray 0.05% (including Nazivin Sensitiv spray).

Instructions for use and dosing regimen

Nazivin drops are intended for nasal administration.

Adults and children over 6 years of age should be prescribed drops of 0.05%, 1-2 drops in each nostril 2-3 times a day.

Children aged 1 to 6 years should be prescribed drops of 0.025%, 1-2 drops in each nostril 2-3 times a day.

Children under the age of 1 year are prescribed drops of 0.01%.

Newborns (children under the age of 4 weeks) are administered 1 drop in each nostril 2-3 times a day.

Children aged 1 month to 1 year (babies and newborns) are prescribed 1-2 drops in each nostril 2-3 times a day.

To ensure dosage accuracy, the 0.01% drop bottle has a graduated pipette with marks for the number of drops. If 1 drop is prescribed, then the pipette should be filled with a solution to the 1 mark.

The effectiveness of the following procedure has also been proven: depending on the age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages.

Nazivin should be used within 3-5 days. Doses higher than those recommended are prescribed at the discretion of the physician.

Side effect

dryness and burning sensation of the nasal mucosa;
sneeze;
feeling of nasal congestion (reactive hyperemia);
anxiety;
insomnia;
fatigue;
headache;
nausea;
with repeated overdose, arterial hypertension, tachycardia are possible;
tachyphylaxis, atrophy and recurrent swelling of the mucous membranes of the nasal cavity (drug-induced rhinitis with prolonged use).

Contraindications

atrophic rhinitis;
angle-closure glaucoma;
children under 6 years of age (drops and nasal spray at a dosage of 0.05%)
hypersensitivity to the components of the drug.

Use during pregnancy and lactation

special instructions

Long-term use and overdose of the drug should be avoided, especially in children.

Influence on the ability to drive vehicles and control mechanisms

drug interaction

With the simultaneous use of Nazivin with MAO blockers or tricyclic antidepressants, an increase in blood pressure is observed.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

Analogues of the drug Nazivin

Structural analogues according to active substance:

4-Wei;
Afrin extra;
Afrin;
Vicks Active Sineks;
Nazivin Sensitive;
Nazol;
Nazol Advance;
Nasospray;
Nesopin;
Knoxprey;
Oxymetazoline;
Oxymetazoline hydrochloride;
Fazin;
Fervex spray from the common cold.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.