Enterosgel® paste for oral administration. Enterosgel - maintains the balance of intestinal microflora! Enterosgel paste 225g instructions for use

In order to neutralize and remove toxins from the body, which can be formed as a result of food, chemical poisoning, develop with rotavirus or intestinal infections, doctors often prescribe enterosorbents. One of the effective and common drugs is Enterosgel, which is widely used for various conditions caused by intoxication of the body. The drug is well tolerated, can be prescribed to children from birth and pregnant women. For the correct use of the drug, before taking it, you need to familiarize yourself with the annotation.

The gel provides a white mass with a jelly-like structure, has white lumps, which is the norm for the drug. Packed in plastic bags of 45 or 225 g, or in cans of 225 g.

Paste - white, odorless, 15 or 45 g. Packages are contained in a cardboard box. Enterosgel in the form of a paste is sold in jars of 225 g.

Description and composition

Enterosgel is a drug from the group of enterosorbents. It is used in various fields of medicine for the treatment of diseases or conditions in which there is intoxication of the body.

The drug has the ability to adsorb toxic substances from the intestinal lumen, including bacteria, allergens, pathogenic microbes, metabolic products and other substances that disrupt the work human body. The drug has very good reviews. Many emphasize the fact that Enterosgel can be given to children from birth, which indicates the safety of the drug, the absence of all sorts of risks after taking it.

The use of the drug allows not only to cleanse the body of harmful compounds, but also to cover the intestinal mucosa with an invisible film that will protect against erosive processes, increase immune defense, neutralizes all harmful toxins that have entered the body. The advantage of the drug is the fact that when it is taken, other physiological processes of the body are not affected, the work is not disturbed. internal organs and systems.

The active ingredient of the drug is polymethylsiloxane polyhydrate. 100 grams of the drug contains 70 mg of the active substance, which, due to its structure, absorbs toxic compounds in the human body.

Pharmacological group

The instructions for use state that Enterosgel, due to the presence in its composition of the main component of polymethylsiloxane, polyhydrate, has a pronounced enterosorbing, enveloping and detoxifying property. Taking the medicine allows you to remove products of incomplete metabolism, various toxins, allergens, viruses and other harmful substances from the intestines, blood plasma. Enterosgel well eliminates the manifestations of toxicosis, improves the functioning of the stomach, liver, kidneys, removes pathogenic flora. In addition, taking the drug allows you to remove metabolic products from the body.

Indications for use

The gel, as well as Enterosgel paste, is intended to free the body from various intoxication syndromes. The drug is widely used in various fields of medicine. People of all ages can use the medicine, including children, pregnant women and the elderly.

For adults

The main indications for the use of the drug are the following diseases and states:

  1. diarrhea of ​​any etiology;
  2. peptic ulcer;
  3. elevated bilirubin;
  4. alcohol poisoning;
  5. dysbacteriosis;
  6. allergic skin diseases:, rhinitis;
  7. bronchial asthma;
  8. drug, alcohol or chemical intoxication;
  9. toxicosis of pregnant women;
  10. mechanical jaundice;
  11. skin diseases;
  12. pathology of the liver or kidneys.

Enterosgel is recommended for those persons who work in hazardous enterprises, mines, factories with high pollution. The medicine will also benefit people living in areas with high dustiness in the air or a low social level.

For children

For children, the drug can be used from birth. In pediatrics, Enterosgel is often used in the treatment of the following diseases:

  1. intestinal infections;
  2. allergic reactions of the skin and respiratory system;
  3. consequences of taking antibiotics;
  4. newborns;
  5. violation of the intestinal microflora.

Other conditions that cause intoxication syndromes in children may also be indications for prescribing the drug.

Enterosgel can be prescribed for conditions such as toxicosis, fetoplacental insufficiency, vaginal infectious diseases, disruption of the intestines and other acute conditions.

Contraindications

Despite the good tolerability of the drug, the absence of pronounced contraindications for use, Enterosgel has some contraindications:

  • hypersensitivity to the composition;
  • intestinal bleeding.

If the patient's history contains contraindications to the use of the drug, the doctor will prescribe another drug with a similar therapeutic effect, but with a different composition.

Applications and doses

For adults

Adults take 1 sachet of the drug (22.5 g) three times a day or one and a half tablespoons if the drug is packaged in jars. If necessary, the dose of the drug can be increased to 4 doses per day.

For children

  • Up to 5 years - 7.5 g or half a dining room.
  • From 5 to 14 years, 15 g each, which is equal to a tablespoon of medicine.
  • Newborns 2.5 g (half a teaspoon).

The frequency of taking the medicine is 3 times a day. For children, the drug can be diluted with breast milk or water.

In severe forms of intoxication, the dose frequency of taking the drug can be increased up to 6 times a day, but the doctor should prescribe the drug. The duration of the drug is 5 - 10 days, less often the doctor may prescribe a 3-week drug.

For pregnant women and during lactation

Pregnant women can stick to the standard adult dosage of 22.5 mg 3 times a day.

Side effects

The drug is well tolerated, but in some cases, if the composition is intolerant or if a person has a history of contraindications to taking, adverse reactions of the body may appear. A person may complain about:

  • discomfort in the stomach;
  • violation of the chair;
  • nausea.

Interaction with other drugs

Enterosgel is compatible with all medications. However, while taking the drug and other drugs, there may be a decrease in the effect of other drugs, which is explained by the adsorption of the drug.

special instructions

If the patient, in addition to Enterosgel, takes other medications, then the interval between taking the drugs should be at least 1 hour. In the process of taking the drug without prior consultation with the doctor, it is not necessary to reduce or increase the dose of the drug. If the doctor has prescribed a course of treatment, it should not be interrupted, even when the patient has become much better. Enterosgel is a safe drug that removes harmful substances from the body, so there will be no harm from taking it.

Analogues

Instead of Enterosgel, the following drugs can be used:

  1. Enterumin is a substitute for Enterosgel in the clinical and pharmacological group. The enterosorbent is produced in the form of a powder for the preparation of a suspension, which, according to indications, can be given to children, pregnant women and lactating women.
  2. is a substitute for Enterosgel in the therapeutic group. Enterosorbent is produced in tablets that can be prescribed to children, including infants. There are no data on the safety of the drug in pregnant and lactating women.
  3. - enterosorbent, which belongs to the substitutes for Enterosgel according to the pharmacological group. The drug is produced in the form of a powder for the preparation of a suspension with an orange or vanilla flavor, a ready-made suspension. The medicine can be prescribed to patients of all ages, it is allowed to drink it to pregnant and lactating women.
  4. is a substitute for Enterosgel in the therapeutic group. It is produced in powder, from which a suspension is prepared. It can be prescribed to patients of any age as an adsorbent and antidiarrheal agent.

Overdose

Symptoms of an overdose in the practice of doctors have not been met, but still doctors recommend strictly observing the prescribed doses of the drug.

Storage conditions

When storing the drug, it must be protected from sunlight, kept away from children. Storage temperature should not exceed 25 degrees. After opening the jar with the drug, it must be used within 3 months.

The price of the drug

The cost of the drug is an average of 381 rubles. Prices range from 310 to 719 rubles.

Registration number: P N003719/02

Tradename: Enterosgel ® .

Group name: polymethylsiloxane polyhydrate.

Chemical Name: non-linear polycondensation product

1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate.

Dosage form: paste for oral administration.

Composition:

100 g of the drug contains:

Active substance:
Polymethylsiloxane polyhydrate 70 g.

Auxiliary substance:
Purified water 30 g.

Description: Homogeneous pasty mass from white to almost white, odorless.

Pharmacotherapeutic group: enterosorbent agent.

ATX code: A07B.

Pharmacological properties

Enterosgel ® has a porous structure of an organosilicon matrix (molecular sponge) of a hydrophobic nature, which is characterized by a sorption effect with respect only to medium molecular weight toxic metabolites (m.m. from 70 to 1000). Enterosgel ® has pronounced sorption and detoxification properties. in the lumen gastrointestinal tract the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, salts of heavy metals, radionuclides, alcohol. The drug also sorbs some metabolic products of the body, including excess bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis. Enterosgel ® absorbs vitamins and microelements, restores disturbed intestinal microflora and does not affect its motor function.

Pharmacokinetics

The drug is not absorbed in the gastrointestinal tract, it is excreted unchanged within 12 hours.

Indications for use

In adults and children as a detoxifier:

  • acute and chronic of various origins;
  • acute potent and toxic substances, including drugs and alkaloids, salts of heavy metals;
  • of any genesis as part of complex therapy (, non-infectious origin,);
  • purulent-septic diseases, accompanied by severe intoxication, as part of complex therapy;
  • hyperbilirubinemia (viral hepatitis) and hyperazotemia (chronic);
  • in order to prevent chronic intoxication for workers in hazardous industries (professional intoxication with polytropic chemical agents, incorporated compounds, arsenic, oil products, organic solvents, nitrogen oxides, carbon oxides, fluorides, salts of heavy metals).

Contraindications

Individual intolerance to the drug, intestinal atony.

Use during pregnancy and during breastfeeding

Enterosgel ® is not contraindicated during pregnancy and breastfeeding.

Dosage and administration

Enterosgel ® paste is taken orally 1-2 hours before or after eating or taking other medications with water.

It is recommended to mix the required amount of the drug in a glass in a triple volume of water at room temperature or take it orally with water.

  • Dosage for adults: 15 g - 22.5 g (1 - 1.5 tablespoons) 3 times a day.
    Daily dose of 45 g - 67.5 g.
  • Children aged 5 to 14 years - 15 g (1 tablespoon) 3 times a day.
    Daily dose 45 g.
  • Children under the age of 5 years - 7.5 g (0.5 tablespoon) 3 times a day.
    Daily dose 22.5 g.
  • Infants are recommended to mix 2.5 g (0.5 teaspoon) of the drug in a triple volume breast milk or water and give before each feeding (6 times a day).
  • For the prevention of chronic intoxication - 22.5 g 2 times a day for 7-10 days monthly. In case of severe intoxication during the first three days, the dose of the drug can be doubled.

The duration of treatment for acute poisoning is 3-5 days, and for chronic intoxications and allergic conditions, 2-3 weeks. Repeated course on the recommendation of a doctor.

Side effect

Nausea, constipation are possible. With severe renal and / or a feeling of disgust for the drug.

Overdose

Cases of overdose have not been identified.

Interaction with other drugs

It is possible to reduce the absorption of other drugs while taking it with Enterosgel ® .

special instructions

The drug can be used in complex therapy with other drugs, subject to the rule of taking 1-2 hours apart in time before or after taking other drugs.

Influence on the ability to drive vehicles, mechanisms

Effects of Enterosgel® on the ability to drive vehicles mechanisms have not been identified.

Release form

Paste for oral administration

Production site at the address: Lipetsk region, Dankov, st. Zaitseva, d.8

225 g in laminated tubes from combined materials.
Each tube of 225 g, together with instructions for use, is placed in a pack of cardboard.

Paste Enterosgel refers to sorption preparations that have a detoxifying effect. The product effectively cleanses the gastrointestinal tract from metabolites, decay products and vital activity of pathogens, toxins. Enterosgel is used as part of the complex therapy of intestinal infections, poisoning, allergic reactions, diseases of the gastrointestinal tract. The tool is non-toxic and has a short list of contraindications.

International non-proprietary name

Polymethylsiloxane polyhydrate.

Atx and registration number

ATX code - A07BC. Registration number - LSR-003840/09.

Pharmacotherapeutic group

The drug belongs to the group of intestinal absorbents.

Mechanism of action

Absorption of Enterosgel in the gastrointestinal tract does not occur. It does not penetrate into the bloodstream and is excreted from the body after 12 hours unchanged.

Once in the digestive tract, the active substance of the paste binds and absorbs:

  • endogenous toxins (metabolic products of bacteria, viruses, fungi);
  • exogenous toxins (tobacco, air pollutants, drugs);
  • toxic substances, salts of heavy metals;
  • food allergens, aldehydes;
  • some metabolites (excess bilirubin, cholesterol, urea, lipid compounds).

These substances are excreted from the body along with Enterosgel, restoring the disturbed intestinal microflora.

The drug also has a slight anti-inflammatory, antipyretic and antidiarrheal effect, improves the functioning of the kidneys, liver and intestines. Enterosgel protects the mucous membrane of the digestive system from the formation of ulcers and erosions.

In this article, you can read the instructions for use medicinal product Enterosgel. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Enterosgel in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications were observed and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Enterosgel in the presence of existing structural analogues. Use for the treatment of intoxication, poisoning, dysbacteriosis, allergies and diarrhea in adults, children (including infants and newborns), as well as during pregnancy and lactation. The composition of the drug.

Enterosgel- enterosorbent.

Enterosgel has a porous structure of an organosilicon matrix (molecular sponge) of a hydrophobic nature, which is characterized by a sorption effect in relation to only medium molecular weight toxic metabolites (m.m. from 70 to 1000).

Enterosgel has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including bacteria and bacterial toxins, antigens, food allergens, drugs, poisons, salts of heavy metals, alcohol.

The drug also sorbs metabolic products of the body, incl. excess bilirubin, urea, cholesterol, lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.

Enterosgel does not reduce the absorption of vitamins and microelements, helps restore disturbed intestinal microflora and does not affect its motor function.

Pharmacokinetics

The drug is not absorbed in the gastrointestinal tract.

It is excreted unchanged within 12 hours.

Indications

In adults and children as a detoxifier:

  • acute and chronic intoxications of various origins;
  • acute poisoning with potent and toxic substances (including drugs, ethanol, alkaloids, salts of heavy metals);
  • as part of complex therapy for acute intestinal infections of any origin (including toxic infections, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbacteriosis);
  • as part of complex therapy for purulent-septic diseases accompanied by severe intoxication;
  • food and drug allergies;
  • hyperbilirubinemia (viral hepatitis, jaundice of various origins);
  • hyperazotemia (chronic renal failure);
  • prevention of chronic intoxication among workers in hazardous industries.

Release form

Gel for the preparation of a suspension for oral administration.

Paste for oral administration.

Instructions for use and regimen

Enterosgel in the form of an aqueous suspension or paste should be taken orally 1-2 hours before a meal (taking other medications) or after a meal. To prepare an aqueous suspension, the required amount of the drug should be thoroughly rubbed into 1/4 cup of water. Before each dose of the drug, it is recommended to prepare a fresh suspension.

Adults and children over the age of 14: 1 tablespoon (15 g) 3 times a day (45 g).

Children under the age of 5 years (including infants and newborns up to a year of life) 1 teaspoon (5 g) 3 times a day (15 g).

Children aged 5 to 14 years: 1 dessert spoon (10 g) 3 times a day (30 g).

In case of severe intoxication during the first three days, the dose of the drug can be doubled. The duration of treatment is 3-5 days.

In chronic intoxications and allergic conditions, the duration of treatment is 2-3 weeks.

Side effect

  • nausea, constipation;
  • in severe renal or hepatic insufficiency, a feeling of aversion to the drug may occur.

Contraindications

  • intestinal atony;
  • hypersensitivity to the components of the drug.

special instructions

According to available literature data, Enterosgel is used as part of the complex therapy of postpartum endometritis, colpitis, bacterial vaginosis, inflammatory diseases uterus and appendages, with urogenital infections, with caesarean section in the postoperative period. There are literature data on the use of Enterosgel as part of therapeutic measures for late gestosis and placental dysfunction.

The drug can be used in complex therapy with other drugs, subject to the rule of separate intake in time.

drug interaction

With simultaneous use with Enterosgel, it is possible to reduce the absorption of other drugs.

Enterosgel's analogues

Among the structural analogs for active substance the medicine has only one drug analogue: Polymethylsiloxane polyhydrate. However, there is a whole class of other drugs that are similar in mechanism of action to Enterosgel, but are used to prescribe in similar cases:

  • Carbactin;
  • Carbopect;
  • Karbosorb;
  • Polysorb;
  • Sorbex;
  • activated carbon;
  • Ultra adsorb.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

The basis of the drug Enterosgel includes methylsilicic acid in the form of a hydrogel. Enterosgel refers to enterosorbents. It has a detoxifying effect when taken orally. The organosilicon matrix of the methylsilicic acid hydrogel effectively absorbs from the blood (due to the action through the membranes of the villi of the cells of the intestinal mucosa) and from the intestinal contents the products of incomplete metabolic reactions, medium molecular weight toxic substances (with a molecular weight of 70-1000) and incorporated radionuclides. After absorption, they are excreted from the body with feces. It also binds and removes microorganisms (opportunistic and pathogenic). Does not suppress coli-, lacto- and bifidobacteria due to the reduced adhesiveness of normal intestinal microflora. Stops manifestations of toxicosis, normalizes laboratory parameters of urine and blood, improves the functioning of the liver, kidneys and intestines. Prevents the development of erosive and ulcerative lesions of the mucous membrane of the gastrointestinal tract under the influence of aggressive external factors due to the enveloping action. Improves parietal digestion. Activates peristaltic bowel movements, does not cause atony. The drug is not absorbed into the systemic circulation. Stabilizes immune responses through effective detoxification.

Indications for use

A drug Enterosgel shown at:

Infectious and toxic diseases of the liver (viral hepatitis A and B, toxic hepatitis, cirrhosis of the liver, hepatocholecystitis);

Kidney disease, especially with the development of chronic kidney failure(glomerulonephritis, pyelonephritis, polycystic kidney disease, etc.);

cholestasis various genesis, including with the addition of allergic reactions and liver failure;

Diseases of the gastrointestinal tract (enterocolitis, gastritis, colitis, diarrhea, post-resection syndrome, gastric ulcer and duodenum and etc.);

Food and drug allergies, infectious-allergic and atopic bronchial asthma, atopic dermatitis, urticaria, eczema, etc.);

Diarrhea and dyspepsia of non-infectious origin,

Infectious diseases (salmonellosis, food poisoning, dysentery, rotavirus infections);

Intoxication (including narcotic, burn, purulent-septic and alcohol intoxication);

Skin diseases (neurodermatitis, diathesis, etc.);

early gestosis,

Comprehensive treatment of intestinal dysbacteriosis,

Malignant diseases (for detoxification before and after surgery, during radiation or chemotherapy).

Mode of application

Enterosgel assigned inside. The dosage form - paste - is completely ready for use. The duration of treatment is determined individually. On average, the duration of therapy is 7-14 days, in case of severe intoxication, it is possible to increase the dose by 2 times in the first 3 days of therapy. With obstructive jaundice, cirrhosis of the liver, it is possible to prescribe a longer time (2 months or more). Enterosgel should drink plenty of water. Enterosgel should be taken between meals of food (2 hours after taking a meal or medicine, or 1.5-2 hours before taking). The daily dose (45 g for adults) is divided into 3 doses. Single dosage - 1 tablespoon (15 g) - for adults. In pediatrics: children under 3 years old - 1 teaspoon (5 g) 2 times a day ( daily dose- 10 g); children 3-5 years old - 1 teaspoon 3 times a day (daily dose - 15 g), children 5-14 years old - 1 dessert spoon (10 g) 3 times a day (daily dose - 30 g).

Side effects

Constipation may occur (especially in patients with a tendency to constipation) in the first days of taking the drug. With the development of constipation, it is recommended to carry out a cleansing enema (in the first 2 days of application enterosgel).

Contraindications

Enterosgel not prescribed for acute intestinal obstruction. After elimination of intestinal obstruction enterosgel is not contraindicated.

Pregnancy

Enterosgel not contraindicated in pregnancy and lactation.

Interaction with other drugs

Enterosgel can be used in complex therapy, subject to the terms of taking enterosgel in relation to others medicines, including adaptogens, immunomodulators, bacterial preparations (lactobacilli, bifidobacteria) and herbal preparations.