Fenistil properties indications for use. Fenistil drops: instructions, reviews, analogues

Children of different ages suffer from allergies caused by food, medicines, insect bites, etc. This problem is especially relevant for infants. An allergic reaction is manifested by red spots on the skin, itching, swelling, irritation of the mucous membranes. It is important to protect the child from the pathogen, and medicines will help eliminate unpleasant symptoms.

Fenistil is a popular antihistamine drug that quickly eliminates the negative manifestations of allergies. The drug reduces the sensitivity of cellular receptors to histamine. Whether it is possible to give the drug to infants will be discussed further.

Fenistil for newborns: description of dosage forms

The antihistamine is produced in the form of drops, capsules, emulsions and gels. For children, drops and gel are used, which have the following composition:

Fenistil gel for newborns colorless with a neutral aroma:

dimethindene maleate;
benzalkonium chloride;
trilon b;
carbopol;
food additive E1520;
caustic soda;
distilled water.

Drops Fenistil transparent odorless:

dimethindene maleate;
monopropylene glycol;
food additive E420;
distilled water;
sodium phosphate;
preservative E218;
ethanol;
food additive E330;
benzoic acid.

When an allergen enters the body, antibodies begin to be produced. Upon repeated contact with the pathogen, histamine is produced, which enters the bloodstream, causing a rash, swelling and itching.

Fenistil reduces the susceptibility of cellular receptors to histamine. Due to the action of the drug, the capillaries become stronger, the inflammatory process and pain decrease. As a result, allergy symptoms disappear.

Oral drops have a systemic effect, the therapeutic effect appears half an hour after ingestion, they act for 12 hours. The gel is applied externally, and about 10% of the active ingredient penetrates into the blood. Therapeutic action external agent appears almost immediately and lasts from 3 to 4 hours.

Indications

Fenistil for newborns in the form of drops is prescribed in the following cases:

Chronic runny nose of allergic origin.
Allergy to drugs.
Nettle fever.
Angioedema.
Allergy to food.
Allergic cough.
Itching caused by chicken pox, dermatitis, eczema, insect bites, etc.
Colds, such as laryngitis (to relieve symptoms such as irritation of the throat).
(symptomatic treatment).

The gel is prescribed to eliminate the external symptoms of allergies:

Itching on the skin due to nettle fever, dermatosis.
Itchy skin rash due to chicken pox, rubella, dermatitis.
Sun or domestic burns.
After insect bites.
Lichen.

Some doctors advise taking drops for 3 days after vaccination to prevent allergies. However, not all pediatricians approve of this practice, explaining that if the child does not have a predisposition to diathesis, then there is no need to give him the drug.

Application and dosage

Fenistil drops are intended for children from 1 month.

According to the instructions for use, the daily dosage for children up to a year is as follows:

up to 12 months - from 3 to 10 drops;
from 1 to 3 years - from 10 to 15 drops;
from 3 to 12 years - 15 or 20 drops;
from 12 years and older - from 20 to 40 drops.

The drug is taken three times a day, the final dosage is determined by the pediatrician after the diagnosis is established.

You can calculate the daily dose of the drug for allergies yourself:

The dose is determined by the calculation of 1 kg of weight / 0.1 mg of dimethindene. For example, the weight of a child is 5 kg, then 5 (kg) x 0.1 (mg) = 0.5 mg of dimethindene should be received by the infant in 24 hours.
1 ml of the drug contains 1 mg of the main component, so the baby should receive 0.5 ml of the drug.
1 ml of the drug contains 20 drops, 0.5 ml x 20 = 10 drops per day.
The daily portion is divided into 3 times: 10 drops: 3 doses = 3 drops.

Thus, a patient weighing 5 kg should take 3 drops of Fenistil three times. The medicine is given before or after meals. Before use, the medication must not be heated, as its effectiveness will decrease.

For newborns aged 1 month, the drug is diluted breast milk or a mixture, for a child of 6 months - juice or compote. Children 12 months and older take drops in pure form they taste good.

Fenistil is used until the manifestations of allergies disappear, the shorter the therapeutic course, the better. The gel is used for newborns to eliminate external.

Rules for the use of the gel:

To eliminate a skin rash, the product is applied in a thin layer to the damaged area. The frequency of the procedure is from 2 to 4 times in 24 hours.
After treatment, avoid the sun.
Only the skin (forehead, cheeks, chin) is treated with the gel, the agent should not get on the mucous membranes.
Treatment lasts until the symptoms disappear completely. If after 4 days of using the gel the patient's condition has not improved, then you should contact your pediatrician.

Before applying the gel to the delicate skin of the child, you need to clean your hands with antibacterial soap.

special instructions

Fenistil for infants is contraindicated in the following cases:

Patients under 1 month, premature or small babies. Increased chance of stopping breathing.
Hypersensitivity to the components of the drug.
Angle-closure glaucoma.
Lung diseases.
Diseases of the bladder.
Violation of the functionality of the gallbladder.

With an increase in dosage or the presence of a contraindication, the likelihood increases side effects: lethargy, dizziness, drying of the inner membranes, skin rash and tissue swelling. Some patients experience nocturnal (temporary cessation of breathing) up to 12 months. After applying the gel, the skin may dry out, burning, itching, rash may occur.

With too long use, the likelihood of convulsions, heart rhythm disturbances increases, the child becomes lethargic, motor activity decreases, reflexes become dull. If such symptoms appear in an infant, you need to stop taking medicinal product and contact your pediatrician.

Similar anti-allergic drugs

If there is a contraindication in a child, Fenistil can be replaced with antihistamines with a similar mechanism of action. However, it is quite difficult to choose a drug for a patient younger than 12 months, since many antiallergic drugs are intended for children from 6 months and older.

Popular analogues:

Erius antihistamine syrup with desloratadine in the composition is used for patients from 1 year old, it rarely causes adverse reactions.
Agistam is a tablet based on loratadine against allergies, intended for children from 2 years of age.
Suprastinex in the form of drops with levocetirizine is prescribed for children from 2 years of age.
Zyrtec drops based on cetirizine are used to eliminate allergy symptoms in a child from 6 months.

The attending physician will help you choose the right analogue. The average price of Fenistil drops is 400 rubles, and the gel can be purchased for 350 rubles.

Thus, Fenistil is an effective antihistamine that eliminates the manifestations of allergies. The drug eliminates rash, itching, swelling of tissues. In order for the treatment to bring only benefit, before using the medication for the treatment of a newborn, you need to consult a pediatrician.

The composition of the medicinal product

active substance: dimethindene maleate;

1 ml contains dimethindene maleate 1 mg

Excipients: sodium phosphate dodecahydrate; propylene glycol; benzoic acid E 210; trilon B; citric acid monohydrate, sodium saccharin purified water.

Dosage form

Drops oral.

Colorless transparent solution, practically odorless.

Name and location of the manufacturer

Novartis Consumer Health SA / Novartis Consumer Health SA,

Route de Letra, 1260 Nyon, Switzerland / Route de l "Etraz, 1260 Nyon, Switzerland.

Pharmacological group

Antihistamines for systemic use. ATC code R06A B03.

Pharmacological properties"type="checkbox">

Pharmacological properties

Pharmacological. Dimethindene maleate is a histamine antagonist at the level of H1 receptors. At low concentrations, it has a stimulating effect on histamine methyltransferase, which leads to histamine inactivation. It exhibits high affinity for H1 receptors and is a mast cell stabilizer. Maleate does not affect H 2 receptors of dimethindene. It also has local anesthetic properties.

Dimethindene maleate is an antagonist of bradykinin, serotonin and acetylcholine. It exists as a racemic mixture with R - (-) - Dimetinden, which has a more pronounced H 1 -antihistamine activity.

Dimethindene maleate significantly reduces capillary hyperpenetration associated with immediate-type hypersensitivity reactions.

In combination with histamine H 2 receptor antagonists, it suppresses almost all types of histamine action on the circulatory system.

Studies have shown that the effect of a single dose of 4 mg dimethindene drops on skin reactions is determined up to 24 hours after drug administration.

Pharmacokinetics. The systemic bioavailability of dimethindene in the form of drops is approximately 70%. The initial response of the body to the drug is expected within 30 minutes after administration, the maximum response is within 5:00. After taking the drops, the maximum concentration of dimethindene in the blood plasma is reached within 2:00.

At concentrations from 0.09 to 2 µg/ml, the binding of dimethindene to plasma proteins is approximately 90%. Metabolic reactions of dimethindene include hydroxylation and methoxylation.

Its half-life is about 6:00. Dimetindene and its metabolites are excreted by the liver and kidneys.

Preclinical studies on safety, toxicity and genotoxicity did not reveal a risk when using the drug in humans. Studies in rats and rabbits did not reveal a teratogenic effect of the drug. Also, in the course of studies in rats, no effect was found on the ability to fertilize, as well as on the development of the fetus and newborns, when used at doses 250 times higher than those for humans.

Indications

Symptomatic treatment allergic diseases: urticaria, seasonal (hay fever) and year-round allergic rhinitis, allergies to drugs and food.

Itching of various origins, except associated with cholestasis. Itching in diseases with skin eruptions such as chickenpox. Insect bites.

Auxiliary remedy for eczema and other itching dermatoses of allergic origin.

Contraindications

Hypersensitivity to dimethindene maleate or to any other component of the drug. The patient has stenosis duodenum/ gatekeeper.

Appropriate safety precautions for use

As with other antihistamines, caution should be exercised when using Fenistil in patients with glaucoma, with impaired urination, incl. with prostatic hypertrophy, and chronic diseases lungs.

As with all H 1 receptor and partly H 2 receptor antagonists, this drug should be used with caution in patients with epilepsy. Antihistamines can cause agitation in children.

Use during pregnancy or lactation.

In animal studies, no teratogenic effect of dimethindene and any of its direct or indirect harmful effects on pregnancy, embryonic development and / or postnatal development have been identified. However, since there is currently no information on the use of the drug during pregnancy, Fenistil drops can be prescribed only when it is absolutely necessary. It is not recommended to take the drug during breastfeeding. If necessary, breastfeeding should be discontinued for the period of treatment.

The ability to influence the reaction rate when driving vehicles or operating other mechanisms

When taking Fenistil, it is possible to slow down the speed of psychomotor reactions, the occurrence of drowsiness, dizziness, so you should refrain from driving a car or working with mechanisms.

Children

Do not administer to children under the age of 1 month, especially premature. With caution, prescribe the drug in the form of drops to children under 1 year of age, sedation may be accompanied by episodes of sleep apnea. In young children, antihistamines can cause agitation.

Fenistil drops can be used in children aged 1 month to 1 year only after consulting a doctor and if there are clear indications for treatment with antihistamines. Do not exceed the recommended dose.

Dosage and administration

Adults, children over 12 years of age and elderly patients.

The recommended daily dose is 3-6 mg, divided into 3 doses - 20-40 drops 3 times a day. For patients prone to drowsiness, it is recommended to prescribe 40 drops at bedtime and 20 drops in the morning, during breakfast.

Children.

Taking the drug is recommended after consulting a doctor, children aged 1 month to 1 year can only be used after consulting a doctor. The recommended daily dose is 0.1 mg (i.e. 2 drops) per kg of body weight per day, divided into 3 doses.

20 drops = 1 ml = 1 mg dimethindene maleate.

Fenistil drops should not be exposed to high temperature. In a bottle of warm baby food, they should be added immediately before feeding. If the child is spoon-fed, the drops can be used undiluted, in a teaspoon. Drops have a pleasant taste.

The duration of the course of treatment is determined by the doctor individually.

Overdose

With an overdose of Fenistil, oral drops, as well as other antihistamines, the following symptoms may occur: depression of the central nervous system(CNS), drowsiness (mainly in adults), CNS stimulation and anticholinergic effects (especially in children), including agitation, ataxia, tachycardia, hallucinations, convulsions, tremors, urinary retention and fever. Also, after this, the development of arterial hypotension, commas and cardiorespiratory collapse is possible.

There is no specific antidote for overdose of antihistamines. Standard measures should be taken, including taking the patient activated charcoal, saline laxative, and taking measures to maintain the functions of the cardiovascular and respiratory systems. The use of stimulants is not custom. Vasoconstrictors can be used to treat arterial hypotension.

Side effects

The main side effect of the drug is drowsiness, especially at the beginning of treatment. In very rare cases allergic reactions may occur.

Tradename: Fenistil®

International non-proprietary name: dimetindene.

Chemical Name: 2-(2-dimethylaminoethyl)-3--(1H)-indene maleate.

Dosage form: drops for oral administration.

Description: colorless, clear liquid practically odorless.

Composition:

the active substance is dimethindene maleate.

1 ml of drops for oral administration contains 1 mg of dimethindene;

inactive substances - liquid sorbitol (non-crystallized), sodium dihydrogen phosphate dihydrate, methyl parahydroxybenzoate, ethanol 96%, purified water.

Pharmacotherapeutic group

Antiallergic agent - H1-histamine receptor blocker.

ATX code

Pharmacological properties

Antihistamine, antiallergic and antipruritic agent. H1-histamine receptor blocker, is a competitive histamine antagonist.

The drug reduces the increased capillary permeability associated with allergic reactions.

It also has antikinin and weak anticholinergic effects. When taking the drug during the day, there may be a slight sedative effect.

Pharmacokinetics

Quickly and fairly completely absorbed when taken orally. Bioavailability about 70%. The time to reach the maximum concentration of dimetindene in blood plasma after oral intake drops - 2 hours Communication with plasma proteins - 90%. It penetrates well into tissues. Metabolized in the liver by hydroxylation and methoxylation. The half-life is 6 hours. It is excreted in the bile and urine (90% as a metabolite and 10% unchanged).

Indications for use

Allergic diseases:, year-round, angioedema, and drug allergy.

Skin itching of various origins (eczema, itchy dermatoses; measles, rubella, chicken pox, insect bites).

Prevention of allergic reactions during hyposensitizing therapy.

Contraindications

Hypersensitivity to dimethindene and other components that make up the drug. Angle-closure glaucoma, prostatic hyperplasia, children under 1 month of age, especially premature.

Pregnancy 1st trimester. lactation period.

Carefully

Care should be taken when prescribing the drug to patients with bronchial asthma and chronic obstructive pulmonary disease.

Caution is also required when prescribing Fenistil® drops to children under the age of 1 year, since their sedation may be accompanied by episodes of sleep apnea.

Application during pregnancy

The use of Fenistil® during pregnancy (II-III trimester) is possible under medical supervision, only if the expected benefit to the mother outweighs the potential risk to the fetus.

Dosage and administration

For children aged 1 month to 12 years, the doses are shown in the table. Multiplicity of appointment - 3 times a day.

20 drops = 1 ml = 1 mg dimethindene maleate.

For adults and children over 12 years old, the daily dose is usually 3-6 mg (60-120 drops), divided into 3 doses, that is, 20-40 drops 3 times a day.

Side effects

Drowsiness (especially at the beginning of treatment), nausea, dry mouth and throat, dizziness, agitation, muscle spasm, respiratory dysfunction.

Overdose

Symptoms: depression of the central nervous system (CNS) and drowsiness (mainly in adults), stimulation of the central nervous system and anticholinergic effects (especially in children), incl. agitation, ataxia, tachycardia, hallucinations, tonic-clonic convulsions, mydriasis, dry mouth, flushing of the face, urinary retention and fever; decrease in blood pressure, collapse.

Treatment: activated charcoal, saline laxatives, drugs (drugs) to support the activity of the cardiac and respiratory systems (analeptic drugs should not be used).

Interactions with other drugs

Enhances the action of anxiolytics, sleeping pills.

With the simultaneous use of ethanol - slowing down the rate of reactions.

Tricyclic antidepressants, anticholinergic drugs increase the risk of increased intraocular pressure.

MAO inhibitors enhance anticholinergic and CNS depressant actions.

special instructions

Fenistil® drops should not be exposed to high temperatures; when administered to infants, they should be added to a bottle of warm baby food immediately before feeding. If the child is already spoon-fed, the drops can be given undiluted. Drops have a pleasant taste.

Patients whose activities require an increased concentration of attention and quick reactions (driving a car, working with mechanisms) are not recommended to take the drug.

Not effective for itching associated with cholestasis.

Release form

20 ml in a dark glass bottle, equipped with a dropper dispenser made of low density polyethylene and a polypropylene cap, equipped with a first opening control system.

1 bottle, together with instructions for use, is enclosed in a cardboard box.

Best before date

3 years. The drug should not be used after the expiration date.

Storage conditions

At a temperature not exceeding 30 ° C, out of the reach of children. Store the vial in its own carton.

Terms of dispensing from pharmacies

Fenistil drops are available without a prescription.

The price of Fenistil

drops - about 300 rubles.

Buy now for 341.10 rub.* * Product prices may vary

Modern medicine has invented effective medicines that allow you to quickly cope with the symptoms of allergies in babies. However, it must be remembered that although children older than a month can already use drugs such as Fenistil, they are dangerous for newborns due to possible respiratory arrest. But even children under one year old should be given these drugs with great care.

In addition, it is important to understand that Fenistil is a symptomatic agent, it blocks the action of inflammatory agents on tissues, but does not reduce their formation in the area of inflammation. Therefore, the use of the drug must necessarily be combined with measures to eliminate the allergen itself.

Mechanism of action

Fenistil belongs to the group of antihistamines. It blocks receptors in tissues for histamine, a substance that is released in large quantities during allergic reactions. Thanks to this, the drug quickly eliminates such signs of allergy as itching, rashes or hyperemia.

Fenistil also has the ability to reduce the permeability of the vascular wall. Due to this, the release of fluid into the intercellular space slows down and swelling of the tissues is eliminated.

Many parents of young children are interested in the question of how long the drug begins to act. As a rule, the effect of the use of Fenistil is observed within 15-30 minutes after its administration. Therefore, it is especially indicated in acute allergic conditions, and in some cases helps to avoid the injection of antihistamines.

Composition

The main active ingredient of Fenistil is dimethindene. This is an artificially synthesized substance that can suppress allergic reactions and eliminate symptoms such as swelling, itching, redness.

Table - The concentration of the active substance in the dosage forms of Fenistil

Release form and storage conditions

The drug is produced by the Swiss pharmaceutical concern NOVARTIS. In pharmacy chains, Fenistil is presented in the following dosage forms:

drops;
gel;
emulsion;
capsules.

Fenistil in drops is available in 20 ml bottles, it is used for allergies in babies aged from one month to a year, as well as for the treatment of older children. For ease of use, there is a special dispenser with which you can quickly count the required number of drops.

The gel is produced in tubes of 30 g and 50 g, and the emulsion in glass bottles of 8 ml. Capsules Fenistil 24 are in blisters, 10 pieces each.

It is better to store the medicine in a cool place, it is undesirable to expose it to direct sunlight. The best option would be the door of the refrigerator, where the bottle or tube should be placed immediately after use.

For young children, including infants, the most acceptable form of Fenistil are drops, gel or emulsion. Adults and children adolescence for oral administration, capsules are recommended, externally gel (emulsion).

Indications

The main indications for the use of Fenistil in children are various allergic reactions, regardless of the zone of their localization:

allergies to food or drugs;
atopic dermatitis (diathesis);
seasonal hay fever;
angioedema;
itching of the skin of an allergic or infectious cause;
reaction to an insect bite;
prevention of allergic diseases.

There are also recommendations of pediatricians on the use of the drug in order to prevent allergic reactions after vaccination. However, this is not shown to all children. This medicine is prescribed only to patients with a history of hypersensitivity reactions to the vaccine, or suffering from allergic diseases. The need to take Fenistil after vaccination should be clarified with a doctor.

The list of indications for prescribing gel and emulsion is somewhat smaller, since they are used only externally, mainly to eliminate allergy manifestations. Indications for their use are itching and redness of the skin of various origins:

against the background of allergies;
at infectious diseases(rubella, chickenpox);
with neurodermatosis.

In addition, the gel well eliminates the effects of insect bites, and is also used for unexpressed sun or thermal burns.

How to take the drug in drops

Methods of using drugs with dimethindene for internal and external use differ significantly. Therefore, the features of the use of each of these pharmaceutical forms will be discussed below.

Standard dose calculation

The drug is recommended for children from the age of one month. Babies who are on breastfeeding, the right amount of medicine is poured into a bottle of milk formula or into water. It is not recommended to add the drug to hot liquid, as it may lose its properties.

For children older than three years, Fenistil can not be diluted, but given in its pure form. According to patients, it has a rather pleasant taste.

The medicine is usually taken three times a day. Before giving Fenistil to a baby, you should clarify the daily and single dosage. The latter is determined by dividing the daily amount of the drug into three doses. The table below will help you choose the right dosage of medication for your child.

Table - Doses of Fenistil for children of different ages

This table contains Fenistil dosages for children under one year of age who have weight and height corresponding to age norms. For children with low body weight, it is recommended to calculate the amount of the drug individually.

Individual dosages

The calculation is made on the basis that the daily amount of Fenistil should be 0.1 mg per kilogram of the child's body weight. It is also taken into account that 20 drops of the drug contain one milligram of the active substance (dimethindene). The calculation sequence is in three steps.

We determine the daily dosage. Example: the weight of a child is 5 kg, so 0.1 × 5 = 0.5 mg. Thus, the daily dose is 0.5 mg.
We calculate the number of drops per day. Example: 20 drops × 0.5 mg = 10 drops, the daily amount of Fenistil will be ten drops.
Calculation of a single dose of the drug. We divide ten drops into three doses, approximately three drops are obtained.

After receiving the daily and single dosage, you should compare it with the data in the table. If the calculated data exceed the tabular data, it is better to consult a pediatrician and once again clarify the medication regimen.

Duration of administration and prophylactic doses

Most often, the duration of admission and how to take Fenistil for children is determined by the pediatrician. Usually this drug is prescribed for five to seven days.

If Fenistil is taken to prevent a post-vaccination reaction, then it should be given three to five days before vaccination, and two to three days after. Recommended prophylactic dosages are shown in the table.

Table - Prophylactic doses of Fenistil for children of different ages

Fenistil gel, emulsion

They are recommended for children of any age, including newborns. Apply Fenistil to dry skin without visible traumatic injuries (cuts, abrasions). First, a small amount of gel is squeezed out of the tube and evenly distributed in a thin layer on the site of a rash or insect bites. The emulsion is applied using a special roll-on applicator. The procedure is repeated two to four times a day.

After applying the drug to the skin, it is not recommended to stay in the open sun for a long time. It is also necessary to ensure that the child does not put the gel into his mouth or eyes with his hands. This is especially true in cases where it is necessary to treat the face area.

The duration of use depends on the severity of skin manifestations of allergies. With significant itching, it is allowed to combine the gel (emulsion) and Fenistil drops.

Contraindications and side effects: is it safe to use Fenistil for the treatment of newborns

children under the age of one month. Under no circumstances;
children of any age. In the presence of allergies or individual intolerance to dimethindene and other components of the drug.

There are also contraindications for the use of the drug in bronchial asthma or having glaucoma.

As a rule, children tolerate Fenistil well, and therefore it is widely used in pediatric practice. Very rarely, side effects may occur:

daytime sleepiness;
nausea;
feeling of dryness in the mouth;
dizziness;
increased nervous excitability;
skin rashes;
muscle spasms;
respiratory disorders, especially in children under one year old.

Parents of the child must strictly observe the dosage of the medicine and in no case exceed it. Otherwise, overdose symptoms may occur:

cardiopalmus;
convulsive twitches;
temperature rise;
urinary retention;
excitation;
severe drowsiness.

If these symptoms appear, you should immediately seek medical help.

It must be remembered that children under one year of age can be given the drug with great care and only as directed by a pediatrician. And in babies up to a month, any dosage forms of the drug administered orally are prohibited. That is, Fenistil capsules and Fenistil drops for newborns are contraindicated.

Where to buy the drug

You can buy Fenistil drops or gel in a retail pharmacy chain. It usually does not require a doctor's prescription to purchase it. However, before using Fenistil to treat a child, especially younger than 1 year old, you should consult a pediatrician.

The average cost of a drug in pharmacies is:

Fenistil drops, 20 ml - 370 rubles;
Fenistil gel, 30 g - 390 rubles;
Fenistil gel, 50 g - 490 rubles;
Fenistil emulsion, 8 ml - 380 rubles.

Prices are as of June 2017.

Also, pharmacists can offer cheaper analogues containing another active ingredient (Loratadin, Cetrin, Diphenhydramine, Diazolin).

Fenistil is enough effective medicine, capable of stopping allergic manifestations and skin itching in small child. The external forms of the drug Fenistil are especially good: they are suitable for infants and newborns as well as for adults. But when taking the drug inside, it is necessary to strictly adhere to the dosage and frequency of administration. Only in this way the likelihood of side effects will be minimized, and the positive properties of Fenistil will help eliminate allergy symptoms.

To prevent an allergic reaction or in a situation where an allergy has already appeared in a child, drugs from the group of antihistamines are prescribed. One of the most popular in childhood drugs of this group is Fenistil. It is often prescribed to children in the form of drops, so parents should know in which cases such a medicine is indicated, from what age it is permissible to use it, and what dosages of Fenistil are used for children.

Features of Fenistil in drops

This dosage form is produced in a glass bottle with a capacity of 20 ml of dark color, supplemented with a special dispenser.
The liquid inside the bottle is clear, odorless, with a sweet taste.
The medicine is safe for infants, so doctors often prescribe it for allergies in children older than 1 month.
Drops are convenient to dose and easy to mix with baby food or drink.
The active substance in this preparation is dimethindene maleate. One milliliter of Fenistil drops contains 1 mg of this active ingredient.
1 ml of the drug contains 20 drops.
Additional substances in Fenistil drops are water, sorbitol, preservative, ethyl alcohol, sodium dehydrophosphate. Also in pharmacies there is Fenistil new, the main difference of which is the absence of ethanol in the composition.
The medicine is produced not only in drops, but also in the form of a gel, as well as in encapsulated form.
Fenistil drops are stored at a temperature not exceeding +25ºС in a place where a child cannot reach. Once opened, the vial can be stored for up to 24 months.

Action

The drug blocks receptors that are sensitive to the compound released during allergies - histamine. In healthy children, such a compound is located inside the cells, but during a pathological process, for example, when exposed to an allergen, histamine begins to be actively released into the blood. The result of this process is tissue swelling, smooth muscle spasm, blood stasis in small vessels, itching and other allergy symptoms.

When taking Fenistil, the production of histamine is suppressed, so itching decreases, capillary permeability decreases, which leads to the elimination of edema and other uncomfortable symptoms. Dimetinden begins to act half an hour after application, and the maximum effect is observed after two hours.

Indications

The drug is often prescribed with preventive purpose, for example, after vaccination or before vaccination, if the baby has a tendency to allergies.

Contraindications

Drops of Fenistil are not prescribed if the child has:

Intolerance to any component of the drug.
Bronchial asthma.
Glaucoma in closed-angle form.

It is also important not to forget that the drug is not used in the neonatal period, since its age limit is 1 month old. At the same time, for babies under 12 months old and with chronic pathologies of the respiratory system, the medicine is prescribed with caution in order to prevent nocturnal apnea attacks.

Side effects

The most frequent side effect Fenistil in the form of drops is drowsiness. It manifests itself in most babies in the first days of admission, and then often passes. In addition to drowsiness in children taking this antihistamine, it happens:

Dizziness.
Dry mouth.
Nausea.
Headache.
Muscle spasms.
Rash on the skin.
Disturbed breathing.

Dosage: how many drops to drip?

The required dosage of Fenistil is often calculated based on the weight of the child. The number of kilograms of the child's body weight is multiplied by 2 and the number of drops is obtained, which is the daily dose. It is divided into 3 doses, receiving a single dosage for a particular child.

The average dosages of Fenistil in the form of drops are:

In the first year of life (from 1 to 12 months) - 3-10 drops, taking into account the weight of the child at one time, only 9-30 drops per day.
Children older than one year to 3 years of age - 10-15 drops at a time, the daily dosage is from 30 to 45 drops.
At the age of 3-12 years - at one time from 15 to 20 drops, in just a day from 45 to 60 drops.
Children over 12 years old - 60 to 120 drops as daily dose, that is, 20-40 drops per reception.

If Fenistil is taken before vaccination, the medicine is given to the child 3-5 days before vaccination at the following dose:

Children under one year old - in the morning and in the evening, 4-5 drops.
Babies aged 1-3 years - twice a day, 10 drops.
A child older than three years - 20 drops three times a day.

If the drug causes severe drowsiness in the baby, the daily dosage of the drug can be divided into doses so that the child receives most of the drug at bedtime. For example, a child needs to be given 40 drops of Fenistil per day. You can give 10 drops in the morning, 10 drops in the afternoon and 20 drops at night.

When calculating the dosage taking into account the weight of the child, also compare the daily amount with the allowable amount for a certain age. For children under 1 year old, this is 30 drops, for children 1-3 years old - 45 drops, and for children over 3 years old - 60 drops. If the calculation turned out to be more than these numbers, the dose is reduced and the child is given the drug at the maximum allowable dosage at his age.

Instructions for use

The required number of drops is diluted with a small amount of non-hot liquid, and then given to the child. You can also give drops undiluted.
The drug is given every 8 hours.
Eating does not affect the reception of Fenistil drops.
It is impossible to heat the drug, as it will lose its medicinal properties.

You can learn about the treatment of allergies in a newborn with the help of Fenistil drops by watching the video.

Features of use in infants up to a year

Fenistil is approved for use in infants who are one month old. However, before using the medicine in infants, you should definitely consult a pediatrician. Many doctors do not advise giving such drops for up to a year, as they have a sedative effect and can provoke respiratory arrest at night.

To give drops to a baby, you need to multiply the weight of the child by 2, and then divide the resulting number by 3 doses. After calculating a single dose for a child, the drops are mixed with expressed human milk or a small amount of a warm mixture. As a rule, babies do not protest against such a medicine, because it has a sweet aftertaste.

Overdose

If you exceed the dose of drops, in a child, this situation will be manifested by fever, increased heart rate, dryness in oral cavity. Hallucinations and seizures may occur. Even if the dosage is exceeded once, you should consult a doctor, and if the baby accidentally drank the entire contents of the bottle, you can’t hesitate - call an ambulance immediately. Doctors will prescribe medications to support the heart and respiratory system, and also quickly remove the drug from the body of the crumbs.

Komarovsky's opinion

Komarovsky emphasizes that Fenistil is classified as an antihistamine drug of the so-called first generation, which affects the functioning of the central nervous system. And that is why such a drug has a lot side effects, which are not observed in more modern antihistamines of the latest generation.

In addition, a well-known pediatrician focuses the attention of parents on the fact that Fenistil, like any other antihistamines, is designed to deal only with allergy symptoms, but is unable to eliminate it completely, since it does not affect the cause. He advises to focus on identifying allergens and try to exclude their contact with the child's body.

See more about this in the program of Dr. Komarovsky.