Regulon treats myoma. The use of birth control pills in the treatment of uterine fibroids

About a third of gynecological pathologies are accounted for, which are found mainly in 35-50-year-old patients. They provoke changes in the hormonal status, which most often consist in an excess content of estrogens.

Uterine fibroids, although it is a pathology of benign origin, can lead to the loss of the patient's reproductive functions. Therefore, the disease requires mandatory medical supervision and specific treatment.

Based on a conservative approach, it is considered a priority by doctors and patients, because any, even the most, has certain risks.

Is it always necessary to treat the disease?

It is categorically impossible to leave myoma unattended, ignoring the ongoing changes.

If the fibroid was found at the initial stage of the formation of the node, while it does not tend to increase in size and progression, then the treatment will consist in a systematic visit to the gynecologist, who will observe the behavior of the tumor. Surveillance tactics can be chosen only if the fibroid formations do not show any signs and do not cause discomfort.

The doctor will periodically refer the patient to ultrasound examination to estimate the size of the formation. Such actions are necessary for the timely adoption of the necessary measures in case education begins to grow rapidly.

Most myoma nodes after the onset of menopause resolve on their own or simply become very small.

When is conservative treatment indicated?

Conservative therapy is used for small fibroid nodes (less than 6 cm or 12 weeks of pregnancy).

The goal of conservative therapy is to prevent further growth of the tumor, activate the reduction of its size and prevent possible myoma complications.

Usually indications for conservative antimyoma therapy are the following factors:

• Small node sizes;
• The absence of pronounced clinical manifestations such as unavoidable bleeding or unbearable pain;
• If there are contraindications to surgical treatment.

In addition, conservative therapy is quite appropriate if the fibroid does not compress adjacent urinary or intestinal structures, and does not prevent conception.

Medications for uterine fibroids

Conservative treatment for fibroids is based on taking the following groups of drugs:

1. Medications that help reduce the severity of clinical manifestations. These include hormonal agents, anti-inflammatory and fortified drugs, intrauterine device;
2. Drugs that help reduce tumor size, which include Ulipristal, GnRH agonists, Fribristal, etc.

Such an approach to treatment helps to cope with pain, reduce bleeding and compensate for large blood loss by curing anemia, induce artificial menopause and avoid total removal of the uterine body.

But when choosing such a therapy, it is worth considering that when the medication is over, the original clinical picture will gradually return.

Anti-inflammatory

Treatment of fibroids with the use of anti-inflammatory nonsteroidal drugs is complementary.

Drugs like Wobenzym, Ibuprofen, Nimesil and the like help eliminate spasms and pain, reduce the amount of intermenstrual and menstrual bleeding.

Such remedies are not a panacea and bring only temporary relief.

hormone therapy

Since the fundamental etiological factor of uterine fibroids is hormonal imbalance, then conservative treatment It is based on hormone therapy, in which medications are prescribed that suppress the production of pituitary hormones of the gonadotropic group.

In general, with antimyoma hormone therapy, COCs, antiprostagens and GnRH agonists, antigonadotropins, gestagens, etc. are prescribed.

Combined oral contraceptives

Preparations of the COC group are represented by various drugs produced on a hormonal basis.

Typically, for the treatment of fibroids, the following combinations of hormonal substances are used:

1. Desogestrel + Ethinylestradiol. A similar combination occurs in preparations like Marvelon, Novinet or Mercilon;
2. Norgestrel + Ethinylestradiol. The combination of these hormones is present in Regenidon and Ovidon;
3. Gestodene + Ethinylestradiol. These hormones are found in Lindinet and Logest.

Taking these drugs helps stop uterine bleeding and pain in the lower abdomen. As for the reduction of the nodes, in practice it is possible to achieve a similar effect with the help of combined oral contraceptives only in cases where the size of the formations does not exceed 15 mm.

Therefore, this group of drugs is not a priority in the treatment of fibroids.

GnRH agonists

Preparations of the group of agonists of gonadotropin-releasing hormones cause an artificial onset of menopause, which is achieved by inhibiting the production of gonadotropic hormones. The amenorrhea that occurs in this case is reversible, because it is temporary and stops after the cessation of therapy with GnRH agonists.

Among the funds of this group, drugs based on hormones are most often prescribed, such as:

1. Triptorelin (preparations Dekapeptil, Diferelin and Dekapeptil-depot). The drugs are administered subcutaneously once a day for a month;
2. Goserelin (contained in Zoladex). The drugs are injected subcutaneously or deep intramuscularly into areas of the body such as the abdomen, buttocks or shoulders;
3. Nafarelin (spray endonasal Sinarel);
4. Buserelina. The drug is available in the form of a nasal spray;
5. Leuprorelin. The substance is present in the basis of the drug Lucrin-depot. This medicine is produced in powder form for the preparation of an injection suspension.

When treated with drugs of this group, patients experience adverse reactions due to estrogen deficiency, such as hot flashes and decreased libido, demineralization of bone tissue, lability and frequent depressive disorders. To eliminate side effects, experts often recommend using various therapeutic tactics such as interval, add-back, drow-back, on-off.

In general, GnRH agonists are considered effective in the treatment of myomatous processes. With large formations, they contribute to the reduction of nodes, which facilitates surgical treatment, allowing for an organ-preserving sparing operation.

Antiprogestogens

Among the drugs of this group, Mifepristone is especially known.

This medication is usually used for medical abortion if the pregnancy is less than 9 weeks.

The use of this drug in myomatous processes provokes a short-term regression of the tumor and stops the symptomatic picture.

Therefore, antiprogestogen therapy is often used for the preoperative phase of treatment.

Antigonadotropins

This group of drugs is usually used in cases where other drugs are useless.

The main representatives of this group are products based on active substances like:

1. Danazol. Based on it, drugs like Danogen, Danol, Verodanazole or Danazol are produced;
2. Gestrinone (Nemestran).

These drugs are rarely used because they only smooth out clinical manifestations fibroids, however, do not affect the size of the nodes. Among adverse reactions antigonadotropic therapy, changes in the voice timbre, increased hair growth or profuse acne rashes can be distinguished.

Gestagens

This group of medicines is considered effective and affordable, because the cost of such drugs is relatively low. The action of progestogen drugs is aimed at blocking the production of estrogen hormones by the ovaries. But compared with GnRH antagonists, the severity of the effect of inhibition of hormonal activity is much lower.

Among the most common drugs are:

1. Norkolut;
2. Duphaston;
3. 17-OPK.

Of course, the use of gestagens does not fully justify the treatment, and in some patients, even after such therapy, a worsening of the condition was observed with an increase in the growth of nodes.

HRT-hormone replacement therapy

Such treatment helps to alleviate menopausal symptoms, reduces the likelihood of heart pathologies, prevents destructive changes in bones and atrophy of vaginal tissues.

The use of hormonal drugs in replacement therapy does not always make sense if the patient is in menopause. Usually at this time, tumor growth stops on its own without the use of any drugs. And if you take hormone-containing drugs, the reaction can become unpredictable.

Therefore, in menopausal patients, progestogens with antiproliferative effects, such as Kliogest or Trisequens, are recommended as hormone replacement therapy.

Hormonal drugs

The use of hormone therapy in the treatment of uterine fibroids is considered one of the most commonly used therapeutic methods.

Since the development of the tumor is based on estrogen excess and reduced progesterone activity, corrective hormonal therapy, which contributes to the normalization of hormonal status, ensures the reverse development of myomatous nodes.

Such treatment helps to reduce tumors, the main thing is that the therapy is selected individually, taking into account the characteristics of the patient's condition.

But hormonal therapy should be carried out for a long course, which can last for six months, or even several years. Oral contraceptives like Zhanin or Urozhestan, which are combined drugs, are considered popular with doctors for uterine fibroids. These drugs are usually given for small nodules (>15 mm).

If the formation is larger, then COCs can provoke the progression of the nodes.

In addition, the use of these drugs is justified only in subserous and intramural myoma formations, which are considered the most responsive to the therapeutic effects of drugs. Also, fibroids should not grow rapidly or squeeze nearby structures, disrupting their activity.

Phytoestrogens

Sometimes in the complex conservative treatment of uterine fibroids, phytoestrogens are used - prohormones of plant origin. They take such drugs for a long time until the final recovery occurs.

Unlike some medications, phytohormones are not addictive, because they are perceived by the patient's body as food.

Phytoestrogens are present in many herbal preparations, as well as in cultivated foods, for example:

• In hops;
• Flax;
• Lentils;
• Red clover;
• Tsimitsifuge, etc.

Phytoestrogens are often used as an alternative to HRT when the patient cannot take medication for some reason.

Mirena intrauterine device

Often, with uterine fibroids, an intrauterine device is used. It does not affect the development of the myoma node in any way, however, it can eliminate some specific manifestations of the pathology.

The Mirena spiral has a local effect, it secretes the hormone levonorgestrel in minimal dosages, which reduces the abundance of menstrual bleeding and promotes relief pain syndrome.

The spiral is set for 5 years, while the general condition of the patient does not change, since this hormone is secreted only within the uterine body and does not have access to circulatory system. The Mirena Navy also protects against unwanted conception, without affecting fertility in any way.

Homeopathy

Homeopathy is considered by some experts as an alternative treatment for uterine fibroids, although not all gynecologists agree with this, because homeopathic remedies can help women with early-detected formations, and with advanced fibroids, taking these drugs often turns out to be pointless.

The composition of complex antimyoma therapy often includes homeopathic preparations such as:

1. Cyclima;
2. Claires;
3. Bysanne;
4. Mastodinona, etc.

In terms of safety, homeopathic remedies are considered the most harmless, because they are not able to adversely affect the female body. Produce such drugs from natural ingredients of natural origin.

In addition to the above remedies, other drugs are used in homeopathic antimyoma therapy, for example, Hamamelis, Canadian goldenseal, Sepia, Potassium carbonate, Gold hydrochloride, etc.

Other medicines

Used in the treatment of fibroids and other drugs. For example, with uterine bleeding, which are considered typical for a myomatous tumor, they often resort to the drug Dicinon, which has a beneficial effect on the mucous tissues of the uterine body, normalizing blood clotting.

With an average size of myoma nodes, the drug Genistril, which belongs to hormonal drugs that block progesterone activity, often helps to reduce them.

Especially popular among women are local remedies for the treatment of fibroids such as tampons and suppositories for vaginal and rectal use. These are suppositories based on calendula, propolis, sea buckthorn, Phytoraxin suppositories containing celandine extract are also popular.

vitamins

Myomatous processes in the uterine body are often accompanied by uterine bleeding, and quite plentiful, as a result of which persistent Iron-deficiency anemia. Therefore, in the treatment of fibroids, vitamin therapy is additionally prescribed.

A woman with fibroids needs vitamin K, which helps to increase blood clotting. Since frequent bleeding provokes iron deficiency, it is necessary to take drugs containing this trace element.

No less important for a patient undergoing therapy for uterine fibroids is vitamin E (which significantly affects hormonal status), folic acid and B vitamins.

In addition, the herbal preparation Estrovel is indicated, which contains phytohormones, plant extracts, amino acids and vitamins. The drug helps to normalize the hormonal background and the cycle of menstruation, reduces blood loss and prevents the development of anemia.

Latest medical treatment research

In the spring of 2014, Gedeon Richter presented the latest drug, which is considered by many to be a breakthrough in the conservative treatment of myomatous processes in the uterus.

This is Esmya's medication - an antiprogestogenic hormonal medicine.

The duration of therapy with Esmya in general takes 8 months: 3 months - the 1st course, then 2 months - a break, then 3 months - the 2nd course. The daily dosage is determined by the doctor.

The main substance of the drug is Ulipristal, a substance that suppresses progesterone receptors. The components of the drug inhibit the division of myomatous cell structures, which leads to their destruction.

In addition, under the influence of the drug in the uterine body, the intensity of blood circulation decreases, and, therefore, blood loss due to uterine bleeding, which allows Esmya to be used in preoperative therapy.

Myoma is one of the most common diseases in the field of gynecology. Nodes of various sizes can be found even in young girls. For this reason, the question of the selection of contraceptives for fibroids is especially relevant.

Contraceptives for fibroids, in addition to the key action - protection from unwanted pregnancy, can reduce the growth and formation of nodes.

Benefits of contraceptives

It has been confirmed that the constant use of hormonal contraceptives reduces the increase in the growth of fibroids, and in addition, to a certain extent, stops the occurrence of others. In addition, against the background of fibroids, a woman can develop pathological disorders. Taking hormonal contraception has a beneficial effect on these processes. And directly the constant intake of these drugs will contribute to the treatment of conditions such as:

• Anemia and bleeding. When using oral contraceptives, the amount of menstrual blood is reduced. Correctly chosen hormones can even save a woman from surgical therapy.
• With fibroids, along with nodes, endometrial hyperplasia, polyps and other similar diseases can often be found. Hormonal agents at the same time carry out the therapy of these conditions.
• The use of oral contraception (and other forms of contraception - spirals, patches and others) is beneficial for women with mastopathy, since these diseases are closely related to hormone imbalance.
• Reduced pain during menstruation and severity premenstrual syndrome with correctly selected oral contraceptives.
• The use of OK during premenopause can help a quick transition to the normal course of menopause, which will help solve many of the difficulties that are typical for this period.

In addition, it must be taken into account that it is preferable for women with fibroids not to become pregnant, since the risk of violations during gestation is very likely. Hormonal remedies provide the utmost possible protection when used correctly.

How do they work

Myoma is a hormonally dependent disease. Even if at first it may seem that some pathologies are difficult to notice, with careful diagnosis they are detected in the bulk of situations.

It is believed that the primary or secondary node, even at an early stage of its own formation, expresses inadequate susceptibility to the influence of sex hormones, mainly to prolactin, gestagen and estrogen. In the tumor, the number of receptors for them changes, which subsequently activates its increase. The nodes react atypically to estrogens, and their excessive number helps the tissues grow and the neoplasm becomes denser. As a result, she is no longer able to regress even with a normal hormonal background.

An excessive amount of estrogen leads to a lack of gestagens, and this already contributes to the pathology of the cyclic production of luteinizing and follicle-stimulating hormones by the pituitary gland. In addition, the importance of prolactin in the formation of fibroids is unclear.

It turns out that with nodes in the uterus in a woman, it is possible to find an increase in the production of LH and FSH and an impaired balance of hormones in the genital area.

By using oral contraception, a woman introduces significant corrections to her own well-being. The key effect of contraceptives is through a decrease in the production of LH and FSH on the feedback principle. This fact leads to inhibition of the growth of nodes, even to a certain reduction in their volume.

There is an opinion that synthetic hormones that come with birth control pills bind to receptors in the nodes of fibroids. By this they imitate estrogens and progestogens. However, this does not trigger the subsequent mechanism of fibroid enlargement.

What are the best contraceptives for fibroids

Hormonal contraception can be different in structure and form. The most famous are:

• Monophasic two-component (include estrogen and progestogen in their composition);
• Mini-drank;
• Gestagen funds.

Gonadotropic hormone agonists also provide a contraceptive effect, but are used for therapeutic purposes. This happens for the reason that they cannot be taken for a long time (more than six months) and because they have many secondary reactions.

If we take into account the form of drugs, then the most common are tablets. However, there are other types of hormonal contraception:

• Ring inserted into the vagina (Novaring);
• Spiral (Mirena);
• Patch;
• Intramuscular injections.

What type and form means suitable each specific woman can only be a gynecologist, after the diagnosis.

For small knots

In order to prevent the onset of the disease and with small nodes, the typical means used to stop an unwanted pregnancy will do. It should be selected taking into account the design of the woman, the characteristics of her puberty, and the hormonal background. In addition, the use of mini-pills containing only progestogens and having fewer contraindications for use is effective and safe.

For large nodes

When using hormonal contraception with a bulky tumor, it must be taken into account that the fibroid will not go away on its own. Only with the use of serious drugs (Buserelina and similar drugs) can the volume of fibroids be slightly reduced with further surgical treatment. Simple contraception of a hormonal type will not bring a significant result.

In addition, large formations in the uterus can disrupt its cavity. This can cause incorrect placement of the intrauterine device (including its hormonal form), its movement and lunge.

This fact can cause inconvenience to a woman (pain, even during sexual intercourse, excessive bleeding during menstruation), and even provoke a spiral attack.

When combined with other pathology

Since the appearance of fibroids is closely associated with the production of sex hormones, “brothers” appear together with this disease. For this reason, the selection of contraception must be carried out taking into account this condition. The key options are:

Disease Selection of contraceptives

Anemia and excessive bleeding	The most rational solution in the bulk of such situations is an IUD with progestogen elements. The spiral is placed for a period of 5 years, provides a significant result and can often save you from surgical intervention.
Endometriosis and fibroids	In such a variant, it will be favorable to use not only contraception with the content of estrogens and progestogens, but also monocomponent means. In certain situations, agonists and antagonists will have to be used.
erosion and fibroids	If the cervix is ​​not healthy, then you do not need to use hormonal coils (for example, the Mirena coil). The tendrils of the spiral will additionally irritate the cavity of the epithelium. In addition, pathogens can easily take root on them. For this reason, due to the spiral in the zone of erosive formation, inflammation will always be visible, and this leads to the further development of the disease. For a similar reason, it is necessary to abandon the ring in the vagina. In this embodiment, it is better to use tablets and patches. If there is a need, then it is possible and injectable.
Endometrial disorders	If a violation of the endometrium due to fibroids is detected, simple contraception will not always help. For this reason, it is preferable to use prolonged forms and an intrauterine device.
Mastopathy	If a woman has mastopathy and fibroids, then pills will be the perfect option in this case. They help relieve all signs of tension in the breasts and prevent the progression of the disease.

For young girls

If we take into account age, then up to 30-35 years it is more correct to use products containing estrogens and progestogens in the form of tablets and rings for the vagina. In addition, in such a situation, mini-pills are also suitable. In this age period, there are the least restrictive measures for any drugs.

After 45 years

When approaching menopause, it is necessary to take into account that the number of somatic diseases in a woman increases, as well as gynecological disorders. For this reason, it is more correct to use either non-hormonal methods of contraception, or prolonged forms. They will be able to help a woman gently approach menopause.

After deleting nodes

Modern techniques enable women to remove nodes without removing the uterus itself. After such therapy, the question may arise of how to properly protect yourself and whether the use of hormonal drugs is allowed.

In fact, hormonal drugs should be preferred. They help prevent the formation of new tumors. It is more correct to use tablets or injections containing progestogen. However, mini-pills and even simple single-component tablets may also be suitable. When selecting, it is necessary to take into account age, illness and plans for pregnancy.

Is it possible to treat fibroids with hormonal contraceptives

The constant use of hormonal contraceptives can stop the occurrence of other nodes and, to a certain extent, reduce the growth of old nodes. However, it will not be possible to completely get rid of the nodes by this method. In what situations can hormonal contraception be used to obtain a therapeutic effect:

• For small knots;
• In order to reduce the volume of blood during menstruation;
• If concomitant disorders are present (endometrial disorders, mastopathy, etc.);
• Stage of preparation for surgical removal tumors.

The treatment of fibroids in a woman must be approached individually. Since this violation develops under the influence of many conditions, and only in 2/3 of women, pathologies in the hormonal background are confirmed by laboratory.

Rules for the use of contraceptives for fibroids

The dosage regimen in any particular case is set personally. Only a specialist can determine the most correct reception table. What options can be:

1. Traditional reception for 3 weeks with a break of a week (or dummy pills can be taken during this period). According to this scheme, patches and vaginal rings are used.
2. The use of hormonal agents exclusively in the 2nd phase. As a rule, in the interval of 14-28 days.
3. For prolonged forms - injections are carried out once every 21 days.
4. The intrauterine device is placed for 5 years of continuous use.

Possible complications when taking oral contraceptives for fibroids

Even with the right choice of drugs, there is a certain risk of complications, especially in women who are predisposed to hematopoietic diseases, nervous pathologies, and others. For this reason, it is necessary to carefully take into account all contraindications.

The most common complications:

• Periodic appearance of brown spotting blood discharge. There may even be heavy bleeding. As a rule, similar phenomena can be traced during the body's addiction during the first 2-3 months.
• Headache, migraine. If they occur, you must cancel the funds. If a woman even has cases of migraine in her medical history, then this is a contraindication to the use of hormonal-based oral contraceptives.
• Thrombosis. In particular, representatives of women with various diseases of the heart and blood vessels are subject to this fact. Hormonal contraception increases blood viscosity. For this reason, they may be contraindicated for those people who have had or have problems with blood vessels, heart attacks, strokes, and so on.
• Decreased libido. Determined by hormonal changes.
• A slight increase in the weight of a woman. Usually, no more than 3-5 kg.
• Biliary dyskinesia, especially against the background of disorders that a woman already has. It is expressed by nausea and vomiting.

Hormonal contraception for fibroids can bring results, especially in girls. These funds can reduce the rate of tumor growth, stop the formation of new nodes and free a woman from such diseases in the gynecological field. However, the selection of funds must be taken seriously and this should be done only in conjunction with a doctor.

Doctors' opinion

Almost all experts agree that hormonal contraceptives can help with uterine fibroids. However, they cannot be completely cured.

Alexandra Ivanovna, gynecologist:

Many women come to me with the question of which contraceptives they should use if they have uterine fibroids. The selection should take place individually with each woman, since each has her own reactions and her own medical history. Hormonal contraception can even somewhat reduce the volume of neoplasms with the right selection. But the whole disease cannot be cured only with the use of OK. Moreover, a noticeable result will be only with small fibroids.

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Questions

What birth control pills should be used for uterine fibroids?

Oral contraceptives for uterine fibroids should be taken only under medical supervision. Currently, progestin contraceptives containing levonorgestrel (Microlut) or monophasic combined contraceptive pills containing desogestrel (Novinet, Regulon, Marvelon, Mercilon) can be used to treat uterine fibroids. No other oral contraceptives should be taken for the treatment of uterine fibroids, as they can, on the contrary, provoke increased tumor growth.

I am 44 years old. A year ago, an ultrasound showed that I had uterine fibroids for 7 weeks. Please tell me what hormonal preparation can be used for treatment. Thank you in advance.

For the treatment of uterine fibroids, various methods and treatment regimens are used. Only the attending physician can prescribe the necessary course of treatment for you, taking into account the characteristics of the course of the disease, the presence of indications and contraindications. As a rule, conservative treatment is based on such drugs as: gestagens, for example, Norkolut (the appointment is justified when uterine fibroids are combined with endometrial hyperplasia and adenomyosis), gonadotropin-releasing hormone (aGN-RH) agonists, antiprogestins, for example, Mifepristone is a synthetic steroid that It has both antiprogesterone and antiglucocorticoid activity. We recommend that you visit the attending gynecologist, who will prescribe you adequate treatment.

Which of the drugs (Novinet, Regulon, Marvelon, Mercilon) is the safest for the body? Thank you in advance!

Each of these drugs has its own characteristics, indications and contraindications, while all of them are safe and can be used for up to 5 years without interruption. Only the attending gynecologist can prescribe this or that drug to you after a personal examination, a general assessment of the state of health, the presence of indications and contraindications.

Hello, Please tell me, I took Jeanine for half a year, with a fibroid of 27 mm, a couple of days ago I checked for ultrasound, it became 38-27 mm, I was told that Jeanine is no longer an effective drug. what can you advise? I am planning a pregnancy, is it possible with such a myoma? how to proceed?

When planning a pregnancy, unfortunately, you must first undergo a course of treatment and achieve a stable absence of fibroid growth. We recommend that you first take a blood test for sex hormones, and then personally consult with a gynecologist-endocrinologist, who, after the examination, will prescribe you adequate treatment.

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Contraceptive pills - which are better for women to take and the rating of drugs without side effects

Any modern girl must take care of her health. Therefore, contraception plays an important role in the prevention of unplanned pregnancy. Today, medicine offers a huge range of various means, and a woman has the right to decide for herself which birth control pills to choose for her body.

Contraceptive pills after 40 years

Many women who have reached the age of forty are interested in the question, contraceptive pills - which ones are better to choose for protection and is it possible to choose such funds on your own? Only a qualified specialist will help determine the choice of drugs, who, having assessed the state of health, will be able to offer contraceptives for women after 40 years.

To prevent pregnancy, it is better to give preference to drugs that do not contain estrogen. This type of birth control is called a mini-pill. Their advantage is the ability to prevent the development of endometrial hyperplasia in its infancy. Other non-hormonal contraceptives in the form of ointments and suppositories are prescribed for women whose sex life is not permanent. The main difference between these drugs and the previous type is that they should not be taken daily, but only before sexual intercourse.

The modern pharmaceutical market is represented by a huge number of contraceptives. As a rule, after 40 years, gynecologists try to prescribe oral contraceptives, because. they 100% prevent pregnancy. In this case, the reception should be dosed, any deviations can cause unpleasant consequences. List of the best oral contraceptives after 40 years:

• Depo Provera is a drug sold as an injection.
• Jess - reduces puffiness.
• Marvelon - prevents pregnancy and improves the condition skin.
• Regulon is an effective contraceptive that normalizes the menstrual cycle.
• Silest - inhibits the activity of the egg.

Hormonal contraceptives after 40 years

After forty years, the real salvation for the fairer sex are hormonal preparations. As a rule, women who have reached adulthood complain of deterioration in health and failures of various functions in the body. This is due to the onset of menopause. The following hormonal contraceptives after 40 years can come to the rescue:

• Trisequence. Contains estrogen and progesterone, eliminates the painful symptoms of menopause.
• Femoston. Includes Estradiol, it is advised to use the drug to increase tone bone tissue.
• Janine. Changes the state of the uterine mucosa, affects the appearance of ovulation.
• Novinet. Normalizes the menstrual cycle, reduces blood loss.
• Silest. Suppresses ovulation.

Contraceptive pills after 40 years with myoma

In adulthood, many women experience diseases of the genital organs. The most common disease is uterine fibroids. The main danger of the disease is the formation of nodes that can burst and cause bleeding. Therefore, it is important to choose the right contraceptive. Experts advise giving preference to such contraceptive pills after 40 years with myoma:

• Diana 35. It has an estrogenic, antiandrogenic, contraceptive effect.
• Regulon. Reduces blood loss during menstruation.
• Yarina. Blocks ovulation and increases the viscosity of mucus in the uterus.
• Regividon. Oppressive effect on the production of gonadotropic hormones.

Many young women, when choosing contraceptives, are interested in the question, which birth control pills do not get better? Doctors advise, in the absence of contraindications, to take medium and low-dose hormonal contraceptives, which are convenient to use. Barrier and chemical methods protection (condoms, suppositories) at this age should not be used because of the high probability of pregnancy, but birth control pills up to 30 years old can help:

• Charosetta contains desogestrel. The drug is suitable for breastfeeding.
• Femulen. Increases antisperm aggressiveness.
• Yarina. Changes the properties of the secret (mucus) that is in the cervix.
• Logest. Inhibits the maturation of follicles.

Microdosed birth control pills

For nulliparous young women who are sexually regular, microdosed birth control pills are best suited. The drugs in this group do not have side effects and are easily tolerated by the body. Great for those who have never used hormonal contraceptives. List of the most popular microdosed tablets:

• Qlaira. As close as possible to the hormonal natural background of a woman.
• Jess Plus. It has a cosmetic (antiandrogenic) effect.
• Zoely. Monophasic drug that contains hormones similar to natural ones.
• Lindinet-20. Reduces the occurrence of ectopic pregnancies.
• Dimia. Changes the endometrium and increases the viscosity of the secret, which is located in the cervix.

The best birth control pills for giving birth - rating

For women who have already experienced the happiness of motherhood, low-dose preparations are best suited, which, although they contain estrogenic components, are safe to use. From micro and high-dose drugs in mature women, unplanned bleeding may occur during menstruation. List of the best birth control pills for giving birth:

• Silhouette. Inhibits ovulation, eliminates acne.
• Midian. The action of the contraceptive is aimed at reducing the likelihood of ovulation.
• Milisiston. Treats dysmenorrhea, eliminates functional disorder menstrual cycle.
• Silest. Changes the implantation ability of the endometrium.
• Marvelon. Prevents the maturation of the egg.

The best birth control pills without side effects

Many girls refuse to use birth control pills because of the hormone content. But modern pharmaceutical companies have created the latest drugs, in which the content of synthetic hormones is minimized. This helps to reliably protect women from pregnancy and does not harm the body. At the same time, a decrease in the dose of hormones does not reduce the effectiveness of the drug. List of the best birth control pills without side effects:

• Yarina. Prevents the appearance of edema and weight gain, treats acne.
• Janine. Reduces the intensity of bleeding.
• Regulon. Resolves ovarian cysts, treats dysfunction of uterine bleeding.
• Logest. Prevents the development of many gynecological diseases.

Good non-hormonal birth control pills

Non-hormonal drugs are not taken orally, but are inserted into the vagina. The mechanism of action of such contraceptives lies in the high content of active substances: nonoxynol or benzalkonium chloride. These compounds, damaging the membrane of spermatozoa, destroy them, which leads to the destruction of tadpoles. List of good non-hormonal birth control pills:

• Pharmatex. The activity of the drug lasts for three hours.
• Erotex. In addition to the contraceptive effect, it also has an antimicrobial effect.
• Gynecoteks. The contraceptive effect lasts 4 hours.
• Benatex. The activity of the tablet is maintained for 3 hours.
• Patentex Oval. It has a high contraceptive activity.

Hormonal birth control

The essence of the hormonal contraceptive method is to suppress ovulation. For this, synthetic analogues of sexual female hormones. Hormonal contraception is represented by two types: oral tablets and prolonged means. List of the most popular hormonal contraceptives:

• Regulon. The main advantage of using pills is that the remedy does not add weight to a woman.
• Lactinet. Does not affect the lipid spectrum of the blood.
• Three-regol. Reduces the chance of sperm entering the uterus.
• Femoden. Reduces the susceptibility of the endometrium to fixation of the blastocyst.

Combined birth control pills

To avoid unwanted pregnancy, you can use a new generation of combined contraceptive pills, which include synthetic substances in small therapeutic doses. Depending on the qualitative composition, the following classification of combined products is distinguished:

1. Monophasic (Cilest, Belara, Logest, Demulen, Chloe, Mercilon, Regulon, Ovidon, Non-Ovlon). They contain gestagen and estrogen in a single dosage, painted in the same color.
2. Biphasic (Anteovin). Consist of two tablets painted in different colors.
3. Three-phase (Three-regol, Tri-merci, Triquilar, Triseston). They contain three groups of tablets, which are considered more adapted to the woman's natural cycle.

Cheap birth control pills - names

Inexpensive oral contraceptives contain only female hormones - gestagens and estrogens, expensive drugs additionally include antiandrogens - they have fewer side effects and a lower chance of getting fat. Moreover, the price of such funds is more than 1000 rubles for 28 tablets. Good cheap birth control pills are:

The price of birth control pills

You can buy contraceptives at a pharmacy. In addition, a suitable medicine can be found, ordered in online catalogs and bought in an online store. The cost of drugs, as a rule, depends on the number of tablets in the package, the manufacturer's company, the region where they are sold. Approximate prices for birth control pills:

How to choose birth control pills

To choose the right birth control pills with maximum effect and minimum side effects, you should seek medical advice. Self-selection can cause negative consequences for the body. It is possible to determine the appropriate drug only after analysis. An approximate scheme for the selection of tablets will be as follows:

• consultation of a gynecologist (the specialist must know the height, weight, age of the patient; whether there were abortions / childbirth, the duration and abundance of menstruation);
• analysis for oncocytology;
• contacting a mammologist;
• cluster blood test for biochemistry, including determination of hormone levels;
• OMT ultrasound on the seventh day of the cycle.

Video

Contraceptive pills - reviews

Karina, 29 years old

For a long time I wanted to find a contraceptive from which you can not get fat. A friend advised me to pay attention to Pharmatex. After consulting with a specialist, I bought this drug. This contraceptive medicine should not be drunk, it should be placed inside the vagina before sex. You can't recover from pills.

Olga, 35 years old

My husband and I have been living for 10 years. Became protected only 5 years ago. During this time I tried different methods of contraception. She put a spiral, introduced a special ring. We used a condom, but there are only minuses from it. After consulting with the doctor, I bought inexpensive pills called Regulon. Both are happy with the result.

Elena, 30 years old

Non-hormonal contraceptives have always fascinated me. But I had to pay attention to them during lactation. After studying the reviews on the Internet, after consulting with a doctor, I chose Patentex Oval. The medicine is convenient to use, it is designed for one dose, which protects the body from the load of various medicines.

The information presented in the article is for informational purposes only. The materials of the article do not call for self-treatment. Only a qualified doctor can make a diagnosis and give recommendations for treatment based on the individual characteristics of a particular patient.

sovets.net

2018 Women's Health Blog.

The female hormonal background determines her health, general well-being and even mood. But there is also a feedback - stress, pathology from the side various bodies can affect the balance of hormones.

Interference with the natural fluctuation of their concentration can lead to serious pathology.

A benign tumor formed from the smooth muscle cells of the uterus is called a fibroid. It develops in women of reproductive age, but most often a few years before menopause.

The nodes can be single and multiple, have a different size, in advanced cases reach several kilograms. For convenience, the size of the fibroids is defined as the correspondence of the volume of the uterus to the gestational age.

The tumor can be located in the thickness of the muscles, closer to the inner cavity of the uterus or under the serous membrane. This determines the development of symptoms.

Causes of the tumor

For tumor growth, a combination of two factors is necessary - uterine trauma and hormonal imbalance. Traumatization can occur regularly - infections, abortions and curettage, childbirth with damage to the walls of the uterus or deep ruptures of the cervix.

In theory myometrial hyperplasia develops during the menstrual cycle. Smooth muscle cells appear in which the system of apoptosis (programmed death) is disturbed. Gradually, their number increases and it is they, as growing cells, that are exposed to damaging factors.

Hyperplasia, or an increase in the myometrium, occurs physiologically under the influence of progesterone, the concentration of which in the blood gradually increases after ovulation and the formation of the corpus luteum. An increase in estrogen content supports a further increase in pathological foci.

Some of the changed cells are destroyed by the immune system, and the rest form myomatous nodes. At first, their growth is supported by a periodic increase in estrogen in the blood. With an increase in the size of the tumor, it itself begins to produce a hormone and switches to self-regulation.

Hyperestrogenism can develop through three mechanisms:

• independent conversion of estradiol to estrone by the tumor, which affects the growth of the uterus;
• the location of more estrogen receptors in tumor cells than in normal uterine tissue;
• synthesis of estrogens from androgens in fibroid cells due to the high activity of enzymes of the cytochrome system.

Therapy to shrink the tumor

The sensitivity of fibroids to sex hormones directs treatment to eliminate the cause of tumor growth - increased estrogen. It can be stabilized or reduced in various ways. But hormones cannot be used for every case, there are certain indications:

• slow node growth;
• the uterus is enlarged no more than 12 weeks of pregnancy;
• the size of the foci does not exceed 2 cm;
• there is no violation of the functions of adjacent organs;
• nodes are located intramurally or subsurozno;
• other symptoms are expressed slightly;
• There are no contraindications for groups of drugs.

In some cases hormonal treatment used before the operation to remove the nodes. With its help, they achieve a reduction in the size of the node, which is less traumatic and reduces blood loss during surgery.

Combined oral contraceptives

The drugs in this group consist of two components - estrogen and gestagen. During the reception, ovulation does not occur, which means that there is no increase in progesterone. Estrogen levels are also controlled by COCs.

Therefore, the growth of the tumor is restrained or it regresses backward. But this is possible only with small sizes of fibroids - up to 1.5 cm in diameter, until the mechanisms of autoregulation are formed. The state of the hypothalamic-pituitary system, ovaries and myometrium is normalized.

• Lindinet contains ethinylestradiol and gestodene, one tablet is prescribed once a day at the same time. Start taking from 1 to 5 days of the menstrual cycle, continue along the arrow to 21 tablets. Then they take a 7-day break and resume the course. Price from 400 rubles.
• Jess consists of ethinylestradiol in the form of betadex clathrate and drosperinone. Take from the first day of menstruation according to the arrow on the package to the last pill. No break required. After the first, they immediately move on to the next package. The price is about 1000 rubles.
• Logest includes ethinylestadiol and gestodene. Take from the first day of the cycle on a tablet at one time for 21 days. Take a break, during which menstrual-like bleeding begins. Resume after 7 days. Price from 700 rubles.
• Regulon made from ethinyl estradiol and desogestrel. Reception is carried out as the previous drug. Price from 350 rubles.

GnRH agonists

This group of drugs affects the pituitary gland by binding to gonadotropic hormone receptors, preventing them from stimulating estrogen synthesis. Medical castration develops, the size of the tumor decreases.

The danger is that after the drug is discontinued and the function of its own hormones is restored, the tumor may begin to grow again. This treatment is used before surgery.

• Zoladex is a depot form for subcutaneous administration. The capsule is placed under the skin on the 2-3rd day of menstruation and left for 28 days. Repeat the introduction within 4-6 months. Price from 8400 rubles per capsule.
• Decapeptyl depot ( active substance triptorellin) is applied once every 28 days under the skin of the abdomen, thighs or buttocks. Treatment up to 6 months. The price is about 8000 rubles.
• Buserelin- nasal spray. Spray into the nose after cleansing it. Apply from the second day of the cycle daily for 4-6 months. Price from 600 rubles.

Antiprogestogens

The drugs of this group are rapidly absorbed into the blood and enter the uterus, where they bind to progesterone receptors in the myometrium. This leads to a decrease in its effect on the uterus. Drugs are contraindicated in fibroids more than 12 weeks of pregnancy.

mefipristone take 50 mg once a day for 3 months. Price from 1500 rubles.

Androgens

The action is based on the inhibition of the steroid function of the ovaries. Thus, the synthesis of estrogens is suppressed, the fibroids regress.

Danazol- the dosage and frequency of administration are selected individually. The minimum effective dose is selected, which should not exceed 800 mg / day. Price for 60 capsules of 200 mg from 19,000 rubles.

Forecast

With conservative treatment using hormones for early stage a complete cure is possible. Often it depends on the number of estrogen receptors in the tumor and its individual sensitivity to hormone therapy.

Fibromyomas of larger sizes, approaching 12 weeks of pregnancy, regress under the influence of drugs. But if the cause of the increase in estrogen is not eliminated, then after the drug is discontinued, a relapse is possible. Therefore, conservative treatment is often used as a preparation for surgery.

The use of oral contraceptives in healthy women reduces the risk of developing uterine fibroids for two reasons:

1. The hormonal background is normalized, the secretion of hormones by the ovaries is reduced, they are in the resting phase, there is no ovulation.
2. No risk of getting pregnant and complete everything with an abortion, which injures the uterus, causes hormonal failure and contributes to the development of fibroids.

HRT

After removal of the uterus, the blood supply to the ovaries is disturbed, their hypofunction and gradual atrophy develop.. Therefore, the concentration of estrogen in the blood decreases. This leads to the appearance of endocrine, metabolic, vegetative and psychological disorders. Hormone replacement therapy helps eliminate the symptoms of hypoestrogenism.

In women with a removed uterus, there is no risk of developing tumors of the mucous layer of the uterus, in contrast to the processes that occur during natural menopause. That's why the hormonal background helps to restore pure estrogens, without the addition of progesterone.

This therapy helps to:

• tides and temperature drops stop;
• blood pressure normalizes;
• attacks of shortness of breath and tachycardia stop;
• the condition of the skin and hair improves, sweating stops;
• eliminates vaginal dryness;
• the risk of developing osteoporosis is reduced;
• the mental state returns to normal, the mood rises, the woman comes out of depression.

Gradually, their ovaries, which were left after a hysterectomy, begin to function. But with severe manifestations of the posthysterectomy syndrome, HRT is continued until the age of the natural onset of menopause.

Prevention

To prevent the development of a tumor, a woman must take care of her health. The body must perform its function. Just as breastfeeding reduces the risk of developing breast cancer, having children reduces the chance of fibroids.

At a young age, for the purpose of prevention, it is necessary choose the right methods of contraception to prevent abortions. The best choice, if there are no contraindications, is oral contraceptives.

Obesity, eating foods rich in animal fats and excess cholesterol contribute to hyperestrogenism.. In adipose tissue, the androgens produced in the female body are transformed into estrogens, their excess occurs. Therefore, women with increased body weight, but not yet obese, fall into the risk group for the development of fibroids.

Chronic stress leads to a tense state of the female reproductive system. Excessive stimulation of the hypothalamic-pituitary system leads to stimulation of the adrenal glands. Their area increases, the production of cortisol increases. This hormone is able to cause the deposition of adipose tissue, the menstrual cycle is disturbed.

Possible excessive hair growth. It also increases the production of androgens, which in adipose tissue are transformed into estrogens. This is how elevated level female sex hormones, which contributes to the development of fibroids.

Therefore, for the purpose of prevention, it is necessary to avoid nervous overstrain, engage in auto-training in order to reduce the level of anxiety and stress.

IN connection with the well-known "originality" of our country, only in the last decade the problem of contraception has attracted due attention of doctors and the public. The question arose about the possibility of using certain methods of contraception in different age groups and in the presence of various diseases.

So, although uterine fibroids is one of the most common gynecological pathologies, there are still no clear ideas about contraceptive methods that are acceptable in women suffering from this disease.

More recently, the vast majority of patients with fibroids underwent supravaginal amputation of the uterus, which in itself was considered "the most reliable method of contraception" for this group of women. In many respects, this situation was due to the then-existing idea that uterine fibroids are an estrogen-dependent tumor that can become malignant, as well as the lack of opportunities for early diagnosis of the disease. Currently, uterine fibroids are increasingly being diagnosed at a younger age in women who are sexually active and planning a pregnancy, which makes hysterectomy excluded from the list of contraceptive methods offered to these women.

As a result of recent studies of uterine fibroids, it was possible to take a different look at the nature of this disease. According to modern ideas, uterine fibroids - monoclonal, hormone-sensitive proliferate (formation), consisting of phenotypically altered smooth muscle cells of the myometrium. As it turned out, h The frequency of occurrence of this disease in the population ranges from 70 to 85% - such indicators were given by a thorough analysis of the autopsy material. Uterine fibroids, manifested by various symptoms, occurs in 30-35% of women over the age of 40, while in a significant proportion of women this disease is asymptomatic.

The issue of oncological alertness in patients with uterine myoma has also been revised. It has been established that the potential for malignancy in fibroids and normal myometrium is the same, that is, in the case of the formation of leiomyosarcoma in patients with uterine myoma, the process occurs de novo, and not due to malignant transformation of the myomatous node. In addition, the incidence of leiomyosarcoma is only 0.3%.

Regardless of how the precursor cell of uterine fibroids originated, its further growth is determined by a number of factors. In particular, these include: dysregulation of genes belonging to the high mobility group proteins family, disturbances in the balance of various growth factors and their autocrine and paracrine regulation, dysfunction of local enzyme systems and dysregulation of the synthesis and degradation of connective tissue. According to the results of our research, trigger factors that initiate and/or maintain the growth of uterine fibroids include : infection, traumatic effect on the endometrium and / or myometrium (as a result of invasive medical interventions) and endometriosis. Apparently, the listed trigger factors are links of one process.

The understanding of the role of various sex hormones in the pathogenesis of uterine fibroids has also changed significantly. If earlier the main role in maintaining the growth of the myomatous node was attributed to estrogens, it has now been proven that the growth of fibroids is mainly stimulated by progesterone, while estrogens play only an auxiliary role.

Today, enough data have been accumulated that allow in the vast majority of cases to resort to medical or organ-preserving surgical treatment of patients with uterine myoma. Every year, the number of women with uterine fibroids who have not undergone the "old-fashioned" hysterectomy, that is, women who have undergone drug reduction of nodes to clinically insignificant sizes or conservative myomectomy, is growing. It is for this group of women that the question of choosing a method of contraception is extremely relevant.

Sterilization, barrier methods, calendar method, coitus interruptus - it is obvious that, in principle, all these methods of contraception are acceptable in patients with uterine myoma. That is why we will dwell here in more detail on such an aspect of the problem as the use of hormonal agents.

Oral contraceptives

Oral contraceptives (OCs) are one of the most common hormonal methods of contraception. According to a study involving a large group of women, it was shown that long-term use of oral contraceptives reduces the risk of developing uterine fibroids . In particular, with a five-year duration of taking OK, the risk of developing uterine fibroids is reduced by 17%, with a ten-year duration - by 31%. A more differentiated statistical study, including 843 women with uterine fibroids and 1557 women in the control group, found that the risk of developing uterine fibroids decreases with increasing duration of continuous OC use. The authors suggested that the mechanism by which OC prevent the development of uterine fibroids is most likely associated with the progestogen component.

The type and amount of the progestogen component of the OK also matter in the complex effect of the contraceptive on the risk of developing uterine fibroids. Immunohistochemical studies of one of the representatives of the third generation of gestagens - desogestrel revealed its ability to have a blocking effect on progesterone receptors, which probably explains the mechanism by which OCs have a preventive effect, since, as noted above, progesterone is the main hormone that stimulates the growth of uterine fibroids .

Taking oral contraceptives has not only a preventive effect. If a woman has uterine fibroids, OK, in particular, containing desogestrel or other representatives of the third generation of gestagens, are able to stabilize the size of myomatous nodes, also due to competitive inhibition of progesterone receptors. However, the growth of myomatous nodes is not always effectively stabilized by taking OK. As a result of our research, the stabilizing effect of OC extends to myoma nodes up to 1.5 cm in diameter, the appointment of OC for large nodes can have both a positive and a negative effect (myoma growth). Apparently, this is due to the fact that the main pathological vicious circles (local enzyme systems, autonomous production of connective tissue) have not yet been fully formed in small myomatous nodes, and therefore the growth of such a node is controlled by the exogenous effect of progestogen OK, which is weaker. » in comparison with other drugs used in drug treatment uterine fibroids (GnRH agonists, mifepristone, etc.).

Thus, long-term use of oral contraceptives significantly reduces the risk of developing uterine fibroids. The use of OK by patients with uterine myoma should be differentiated. If the size of myoma nodes does not exceed 1.5 cm in diameter, the appointment of OK (especially those containing third-generation progestogens) is not only not contraindicated, but is also one of the most effective means of preventing further growth of fibroids. In the event that the size of the nodes is larger, then such patients should undergo a drug reduction in the size of the nodes to the maximum possible. In the future, such women can use OK, which, in addition to the contraceptive effect, will prevent the recurrence of uterine fibroids. In cases where conservative myomectomy is unavoidable, women can use OCs after removal of myoma nodes, which will also provide reliable contraception and relapse prevention. In other words, oral contraceptives are possible and even indicated for women with small nodes. In the presence of large myomas, oral contraceptives are also possible and indicated to be taken, but only after treatment.

Intrauterine devices

Intrauterine devices are a common method of contraception, especially in the older age group. There are three types of intrauterine contraception: the copper intrauterine device, the progesterone-releasing intrauterine system, and the levonorgestrel-releasing intrauterine system.

copper spirals are the most widely used in the world. The mechanism of action is associated with the spermicidal activity of copper and the reaction of the endometrium to foreign body, which disrupts the processes of fertilization and nidation. The only purpose of this type of spirals is contraception.

Such spirals can be used by women with uterine fibroids if the myoma nodes have not deformed the uterine cavity. The use of this type of spirals will provide only a contraceptive effect, however, it must be remembered that in case of insufficient decontamination of a woman before installing the spiral, there is a high probability of developing inflammatory processes, which will lead to the growth of myomatous nodes.

progesterone releasing system mainly provide their contraceptive effect by changing the properties of cervical mucus and the reaction of the endometrium to a foreign body. Their term of use is limited to 12 months. Given the role of progesterone in the pathogenesis of uterine fibroids, the use of such spirals in patients with myoma is contraindicated.

Intrauterine levonorgestrel-releasing system (Mirena) is a polyethylene T-shaped system containing a container that contains levonorgestrel. This container is covered with a special membrane that provides a continuous controlled release of 20 micrograms of levonorgestrel per day. The term of effective contraception when using Mirena is 5 years.

Unlike other intrauterine contraceptives, Mirena has a number of non-contraceptive effects. The use of Mirena leads to a decrease in the volume and duration of menstruation and, in some cases, to oligo- and amenorrhea. It was this effect that became the basis for the use of Mirena in patients with menometrorrhagia associated with uterine myoma and adenomyosis. As a result of a series of studies, including a large number of women with uterine myoma and adenomyosis, accompanied by menometrorrhagia, it was reliably shown that the introduction of Mirena leads to the normalization of menstrual function, a significant decrease in the volume and duration of menstruation, amenorrhea develops in 20-25% of cases, hemoglobin values ​​decrease. back to normal. Against the background of the use of Mirena, there is no increase in the size of myomatous nodes, that is, their stabilization is observed. And in this case, the smaller the size of the myomatous nodes, the more pronounced the stabilizing effect of Mirena.

In addition, the introduction of Mirena is effective tool, providing prevention of recurrence of growth of myomatous nodes and normal volume and duration of menstruation after medical or organ-preserving surgical treatment uterine fibroids.

Obviously, all patients with uterine fibroids, regardless of the size of the nodes, should be adequately treated. The position - "we will observe, we will grow - we will cut off" in modern conditions is a crime! Only after the treatment is carried out, it is necessary to decide on the choice of a method of contraception. The exception is small myomatous nodes, which, as noted above, are stabilized while taking oral contraceptives. Thus, the choice of contraception in patients with uterine myoma is generally determined not only by the preference of one method or another, but also by the need to prevent recurrence of fibroid growth, that is, preference should be given to oral contraceptives containing modern progestogens and intrauterine levonorgestrel-releasing system. It should also be noted that what longer woman takes oral contraceptives, the lower her risk of developing uterine fibroids becomes.

Local funds

The use of all the above contraceptives should take into account all contraindications to their use. In the event that none of the listed drugs can not be used, due to the presence of contraindications to their use, it is possible to recommend the use of local funds, one of which is domestic drug Contraceptin T . It contains oxyquinoline sulfate, boric acid and tannin. Tannin causes mucus proteins to coagulate to form a protective film that prevents the seminal fluid from coming into contact with the vaginal mucosa. Oxyquinoline sulfate has a spermicidal effect. Boric acid creates an acidic environment in the vagina, which is unfavorable for sperm survival. In addition, oxyquinoline sulfate and boric acid have an antiseptic effect.

Literature:

1. Ross R.K., Pike M.C., Vessey M.P., et al. Br. Med. J. 1986

3. Chiaffarino F, Parazzini F, La Vecchia C, et. Br. J Obstet Gynaecol 1999; 106:857-860

Article last updated 07.12.2019

Every 4 women of childbearing age are diagnosed with uterine fibroids. This is a neoplasm that can cause bleeding, anemia, deterioration of well-being, infertility. On the initial stages the disease does not manifest itself in any way, so the diagnosis is often random.

It is not desirable to become pregnant and give birth to a child with fibroids, because there is a high risk of complications, miscarriages, and tumor degeneration. Contraceptive pills for fibroids will help prevent unwanted pregnancy.

You can also use condoms or an intrauterine device for contraception. The use of medications is the most effective option, because it not only prevents pregnancy, but also has a therapeutic effect on the tumor, allowing it to be reduced to an operable size. An experienced doctor should choose the drug. If you drink contraceptives for fibroids without a gynecologist's appointment, this can aggravate the situation, cause problems, uterine bleeding and other complications. The doctor will be able to choose the optimal protection regimen based on clinical picture disease and test results.

Contraceptive pills for uterine fibroids provide effective protection and prevention of various diseases of the reproductive system. The preparations are based on special substances - analogues of female hormones. Myoma develops due to an excess of estrogen and hormonal failure. A properly selected drug and taking the medication according to the prescribed scheme will stop the growth of the node.

Pharmacies offer a wide range of hormonal drugs that are effective for fibroids. They differ in name, composition, dosage and the result obtained. The choice of the appropriate one should be made only after consulting a gynecologist who knows the nature of the disease, the degree of its neglect, the type of node, etc. Artificial hormones, entering the body, block their natural production, which allows you to stabilize the hormonal background. Doctors divide drugs that can affect the tumor into two large groups:

• Combined oral contraceptives for fibroids or COCs. They include estrogen substitutes and progestogen.
• monophasic drugs. Their main distinguishing feature is that each tablet contains an equal amount of active substances and active ingredients.

In practice, COCs are more often used, such as Microlut, Novinet, Marvelon, etc., they have proven themselves well. An effective drug is "Silhouette".

This combined contraceptive with antiandrogenic effect. It is completely absorbed and easily excreted in the urine during the day. The main action of the tablets is the inhibition of ovulation and a change in the structure of the endometrium.

Retail prices for "Silhouette" tablets vary from 650 to 1600 rubles, depending on the geolocation and packaging of the tablets. usually packaged from 21 to 63 pieces.

A course of hormone therapy can reduce the manifestations and symptoms of the disease, such as uterine bleeding and pain. In combination with hormonal drugs can be used folk recipes based on herbs, bee products, plant components. An integrated approach, diet, restriction is welcome physical activity and aces of sun exposure.

Rules for taking contraceptives

When treating fibroids, it is extremely important to follow all the recommendations of doctors. The course and dosage of the drug should be prescribed by a gynecologist, based on the indications of the disease. There are several simple rules, which must be followed when taking COCs, namely:

• taking hormonal drugs should be started from the first day of menstruation;
• do not exceed the prescribed doses;
• it is not recommended to alternate the course with breaks, after the end of the prescribed regimen, treatment should be continued;
• take the tablets systematically, preferably at the same time;
• in case of vomiting, you need to repeat the medication;
• as soon as a woman starts taking COCs, the first two weeks should be protected with a condom;
• if the time of taking the drug was missed or you do not remember when you last took the pill, you need to take the medicine as soon as possible.

It is worth noting that bleeding and vaginal discharge between periods when taking COCs is not an alarming sign, it is necessary to continue the prescribed course. Remember that contraceptives are not a method of treatment, they are intended to exclude conception, and have more of a preventive and anti-symptomatic effect.

Combined drugs are effective if there is a mini node.

If the tumor size is more than 1.5 cm in diameter, COCs are not used.

In this situation, the correct solution would be to remove the tumor by surgery. Today, minimally invasive techniques are actively practiced that reduce pain, the risk of complications and the rehabilitation period.

The effectiveness of birth control pills after 40 years

Often women are interested in whether it is possible to take birth control pills after 40 years? Doctors are unanimous in their opinion that the use of oral contraceptives is not only necessary, but also useful, because it has an excellent therapeutic effect. They not only prevent the conception of a child, but also have a positive effect on general well-being, the body as a whole becomes more cheerful and healthy.

If you systematically use contraceptives after forty years, this will allow you to appreciate the many benefits, namely:

• reducing the risk of developing cancer;
• antisymptomatic action;
• normalization of the menstrual cycle;
• reduction of manifestations of pain syndrome and PMS.

It is believed that a woman enters menopause at the age of 45-50 years. This age indicator is purely individual. Often under the influence bad habits, ecology or genetic predisposition menopause occurs earlier. During this period, menstruation may be absent, but the ability to conceive is still preserved.

The use of contraceptives after the age of 40 eliminates the possibility of pregnancy, and also reduces the negative manifestations of menopause - hot flashes, bloody issues, pain in the lower abdomen, etc.

Before a doctor prescribes oral contraceptives to a patient aged 40+, he needs to conduct an examination, find out if the woman smokes, if she has any diseases of cardio-vascular system whether he lives a regular sexual life, whether there are tumor formations. An important role is played by the state of immunity. If it is weakened, the absorption of drugs worsens, which reduces the effectiveness of the drugs.

Opinions of women about contraceptives for fibroids

The effectiveness of contraceptives for women diagnosed with uterine fibroids is better than any advertisement will be told by the reviews of those who took them.

Irina, 39 years old

“A year ago, a fibroid 2.7 cm in size was discovered. It was diagnosed by chance during a routine examination. The doctor decided to observe, and not immediately operate, for which I am very grateful. Hormonal drugs were prescribed, a diet was developed. They also prescribed contraceptives. The gynecologist said that "Regulon" with myoma is extremely effective, which I was convinced of.

Since the beginning of the drug, I felt an improvement in well-being. During menstruation, she stopped experiencing pain, became calmer. After a year and a half, the size of the fibroids decreased to 1.5 cm. Based on this, I can conclude that the effectiveness of treatment by 50% depends on how competent and experienced your doctor is, and the remaining 50% depends on the drugs used.”

Ekaterina, 45 years old

“When myoma was discovered, the gynecologist prescribed Regulon as a contraceptive. The drug is effective, and most of all I liked the fact that it does not irritate the stomach, does not cause nausea, vomiting and other side effects. I have been taking the drug for a year now. Satisfied with them 100%. I advise everyone."

Zhenya, 33 years old

“Treatment of fibroids is a long and complicated process. Everything is very individual, and what works for everyone does not always work for you.

Before I felt an improvement in well-being, I had to try more than one drug. Basically, the gynecologist prescribed COCs, but they did not help. Then I imputed the doctor, underwent a second examination, and I was prescribed Regulon. This is a monophasic drug, the effect of which I felt after two weeks of taking it. I drink it systematically, but I'm thinking about an operation.

Elina

“I took Silhouette as a contraceptive. It is very convenient that you need to take the tablets at the same time. The body gets used to it and it is almost impossible to forget about the medicine. I like the drug, because it really helps. For a year and a half of admission, there were no problems in the gynecological area.

Tatyana, 47 years old

“When I started menopause (43 years old), the doctor immediately prescribed Silhouette. The medicine helps to prevent the risk of developing tumors, reduces the manifestations of menopause. I almost did not feel hot flashes and other unpleasant symptoms. I still drink Silhouette, while I advise all my friends to use this particular drug during the onset of menopause.

Kirill, 38 years old

“I am a doctor with many years of experience. I can speak firsthand about the effectiveness of Regulon. The drug really works well as a contraceptive, and also allows you to influence the growth rate of the myomatous node.

Marina, 41 years old

“I prescribe Regulon to women diagnosed with fibroids, because I am confident in the effectiveness of the drug. I myself drink pills as a contraceptive, as well as a preventive measure. If you follow all medical recommendations and drink the drug according to the scheme, the reduction of fibroids is noticeable after 3-4 months.