Eye drops Levomycetin: instructions for use, analogues and reviews, prices in pharmacies in Russia. Eye drops Levomycetin: instructions for use for adults and children Levomycetin drops appointment

Levomycetin is an antimicrobial drug. It is used in the treatment of inflammation of a bacterial nature that appears in the conjunctiva or cornea. The advantage of this drug is its slow addiction.

Good to know

Forms of release and active ingredients

Eye drops Levomycetin 0.25% is available in sterile 10 ml bottles. The active component of the drops is chloramphenicol (25 mg in a 1 ml solution).

Auxiliary substances are:

• boric acid,
• purified water.

Applications of ophthalmic Levomycetin

These drops are prescribed for the treatment of eye infectious diseases:

• keratoconjunctivitis,

Sometimes it has a positive effect when other means do not help. This is noted by many patients, whose reviews can be found at the end of the article. According to the instructions, the medicine is applicable to children from 4 months of age.

Therapeutic effect

Ophthalmic Levomycetin is a broad spectrum antibiotic. It produces a bacteriostatic effect on both Gram-positive and Gram-negative bacteria. These include microorganisms that resist the effects of penicillins, tetracyclines and sulfonamides.

As a result of instillation of the drug, its active substance in the maximum concentration is collected in the area of ​​​​the cornea, vitreous body and iris. It does not penetrate the lens.

Who should not use

Levomycetin eye drops are contraindicated in cases of:

• kidney and liver failure,
• hematopoietic disorders,
• hypersensitivity to drug substances.

Women during pregnancy and lactation, as well as babies under 2 years of age, are rarely prescribed this drug. Patients in this category should be cautious about this medicine. Those suffering from psoriasis and eczema can use it only after consulting a doctor.

Possible side effect

Most patients tolerate it well. medicine.A side effect may occur if:

• the drug should be taken simultaneously with drugs that depress hematopoietic function (cytostatics, sulfonamides),
• radiation therapy is performed.

A common side effect is irritation in the eye area. Its symptoms:

• burning,
• increased tearing.

With prolonged use of eye drops, the pathology of the circulatory system may develop:

• thrombopenia,
• leukopenia,
• anemia, etc.

A secondary fungal infection may also occur. With these symptoms, the drug is canceled.

Children from Levomycetin may experience:

• diarrhea,
• vomit,
• decrease in hemoglobin,
• nausea.

After the introduction of drops, a decrease in the clarity of vision is possible. In this situation, it is better to give up driving and activities that require special attention.

Questions of practical use

Instructions for use

The standard scheme prescribes the instillation of Levomycetin drop by drop into conjunctival sac eyes every four hours. In accordance with the instructions, the treatment course should not be longer than two weeks.

With severe inflammation, you can drip every hour. The dosage is determined by the ophthalmologist depending on the characteristics of the disease.

The instillation technology includes the following steps:

1. Shake the bottle with drops.
2. Slightly pull back the head and pull the lower eyelid down. It is better to look far up.
3. Place the bottle over the eye with the open end down, then lightly press.
4. After completing the procedure with one eye, attach the index finger to its inner corner (closer to the nose). Hold it for a few minutes, slightly pressing. Due to this, the medicine stays in the eye longer.

Before using eye drops, soft contact lenses should be removed. Half an hour after the procedure is completed, the lenses can be returned to their place.

At overestimated doses, visual impairment may occur, which is quickly restored. In this case, the eyes should be rinsed thoroughly with plenty of water.

Storage conditions, price and analogues

The shelf life of Levomycetin drops is 2 years. They should be stored in an unlit place, the temperature of which is 8-15 ° C. Once opened, the bottle should not be used for more than a month.

In Russian pharmacies, the average price of Levomycetin eye drops is 19-24 rubles, in Ukraine - 15-19 UAH.

To analogues ophthalmic Levomycetin relate:

Reviews about the effectiveness of Levomycetin

Anna, 39 years old . I had conjunctivitis. The ophthalmologist prescribed me several medicines at once - Tobrex, Ophthalmoferon, Tetracycline ointment. The total amount of 1000 rubles. I don't make that kind of money. The pharmacy pharmacist advised Levomycetin drops for 15 rubles. After three days of prokapyvaniye all has passed or has taken place. Drops are effective and cheap.

Ivan, 27 years old . I suffer from conjunctivitis all the time. Previously used Albucid. It burns the eyes, and white stains remain on the face. Also, no results. Friends advised Levomycetin drops. Of course, you need to consult a doctor. But there is no time. The drops have been very effective. They help great.

Vera, 41 . For many years I have been fighting conjunctivitis with Levomycetin. First, I wash my eyes with furatsilin, and then I drip these drops. For three days, the eyes are normal.

Nina, 31 . I use Tobrex when vision gets a little worse. He acts very slowly. But with swollen eyes, I am saved only by Levomycetin. By evening, the pus decreases, only redness remains. The next morning and she passes. After I finish my treatment with Tobex, it is a little softer. But Levomycetin quickly clears the eyes.

Tatyana, 42 years old . In our home first aid kit, Levomycetin eye drops are constantly present. My husband is an electric and gas welder, he often has problems with his eyes. These drops always save. We treat not only ourselves. Our animals with eye diseases are also well helped. The drops are very cheap and so effective.

Galina, 23 years old . Levomycetin drops are universal. When my eye turned red and started to hurt (I don’t know why), they quickly helped. It stings a little, but it's gone. My sister had barley, so she brought it out with Levomycetin. We even dripped for our hamsters. They fought and hurt their eyes. The drops helped them quickly.

The active substance of Levomycetin in all its forms is chloramphenicol - a substance that belongs to the group of antibiotics amphenicols .

Drops in the eyes contain in their composition chloramphenicol at a concentration of 2.5 mg / ml.

Possible dosages of the active substance for capsules And tablets- 250 and 500 mg, for prolonged-release tablets - 650 mg (tablets have 2 layers - the outer contains 250, the inner contains 400 mg ).

Alcoholic solution of Levomycetin available in a concentration of 0.25; 1, 3 and 5%. Ointment Levomycetin can have a concentration of 1 or 5%.

Preparations from different manufacturers have a different composition of auxiliary components.

All variants of the same drug produced by pharmaceutical companies in the post-Soviet countries differ slightly, since they use the same technology for producing chloramphenicol. Thus, Levomycetin DIA eye drops do not differ from drops produced, for example, by Belmedpreparaty.

Release form

• eye drops 0.25%(ATX code S01AA01);
• liniment 1%, 5%;
• alcohol solution 1%, 3%, 5% and 0.25% (ATX code D06AX02);
• tablets And capsules 250 and 500 mg, 650 mg extended-release tablets (ATX code J01BA01).

pharmachologic effect

Antibacterial. The drug stops inflammation and cures infections of any tissues and organs, provided that they are caused by sensitive to chloramphenicol microflora.

Pharmacodynamics and pharmacokinetics

Levomycetin is antibiotic or not? Antibiotic of synthetic origin, which is identical to the product produced by microorganisms Streptomyces venezuelae in the course of their life.

Chloramphenicol destructive to most gram (+) and gram (-) bacteria (including strains that are resistant to , And ), spirochete , rickettsia , individual large viruses.

Shows low activity against Clostridium, Pseudomonas aeruginosa, acid-fast bacteria and protozoa.

The mechanism of action of the drug is related to the ability chloramphenicol interfere with protein synthesis in microorganisms. The substance blocks the polymerization of activated amino acid residues that are associated with mRNA.

Resistance to chloramphenicol in microbes develops relatively slowly; cross-resistance to other chemotherapy drugs, as a rule, does not occur.

When applied topically, the required concentration is created in aqueous humor, vitreous body fibers, cornea and iris. The drug does not penetrate the lens.

Pharmacokinetic parameters when taking chloramphenicol inside:

• absorption - 90%;
• bioavailability - 80%;
• the degree of binding to plasma proteins - 50-60% (in pre-born
• term of babies - 32%);
• Tmax - from 1 to 3 hours.

Therapeutic concentration in the bloodstream is maintained for 4-5 hours after oral intake. About a third of the dose taken is found in bile, the highest concentration of Levomycetin is created in the kidneys and liver.

The drug is able to pass the placental barrier, its serum concentration in the fetus can reach 30-80% of the serum concentration in the mother. Penetrates into milk.

Biotransformirovatsya mainly in the liver (90%). Under the influence of the normoflora of the intestine, it undergoes hydrolysis with the formation of inactive metabolites.

The elimination time is 24 hours. It is excreted mainly by the kidneys (90%). With the contents of the intestine, from 1 to 3% is excreted. T1 / 2 for an adult - from 1.5 to 3.5 hours, for children 1-16 years old - from 3 to 6.5 hours, for children 1-2 days after birth - 24 hours or more (with low weight body is longer), on the 10-16th day of life - 10 hours.

Patients who have previously received cytotoxic drugs or passed , pregnant women, young children (especially the first 4 weeks of life), the medicine is prescribed for health reasons.

Side effects

Side effects of Levomycetin systemic nature:

• disorders of the digestive system - nausea, , dyspepsia, vomiting, irritation of the mucous membrane of the throat and oral cavity, dysbacteriosis;
• violations of hemostasis and hematopoiesis - reticulocyto-, leuko- and thrombocytopenia, agranulocytosis, hypohemoglobinemia, aplastic anemia ;
• sensory disturbances and nervous system- depression, optic neuritis , mental and motor disorders, headache, impaired consciousness and / or taste, hallucinations (auditory or visual), delirium, decreased visual acuity / hearing;
• hypersensitivity reactions;
• attachment of a fungal infection;
• cardiovascular collapse (usually in children of the first year of life).

When using eye drops, liniment and alcohol solution, local allergic reactions are possible.

Instructions for use Levomycetin

Eye drops Levomycetin: instructions for use

Eye drops Levomycetin (DIA, Akri, AKOS, Ferein) are introduced into the conjunctival sac of each eye, one 3-4 rubles per day. The course of treatment usually lasts from 5 to 15 days.

When using the drug, you should tilt your head back, gently pull the lower eyelid towards the cheek so that a cavity forms between the skin and the surface of the eye, and, without touching the eyelid and the surface of the eye with the tip of the dropper bottle, add 1 drop of medicine into it.

After instillation, the outer corner of the eye is pressed with a finger and does not blink for 30 seconds. If you can’t blink, do it as carefully as possible so that the solution does not spill out of the eye.

For children in the neonatal period (the first 28 days after birth), the drug is used for health reasons.

At purulent otitis media the drug is injected into the ear 1-2 rubles / day. 2-3 drops. With significant discharge from ear canal, which wash off the applied solution, Levomycetin can be used up to 4 rubles / day.

At bacterial rhinitis your doctor may recommend nasal drops.

Eye drops for barley

Application for barley chloramphenicol in combination with , which is part of the solution as an auxiliary component, helps to prevent infection conjunctiva and the development of complications after opening the abscess, accelerates the maturation barley , partially relieves redness and reduces the intensity of pain, reduces the recovery time by 2-3 days.

Treatment is carried out simultaneously for both the patient and healthy eye. The agent should be instilled 1-2 drops 2-6 rubles / day. With severe pain, Levomycetin can be instilled every hour.

Levomycetin tablets: instructions for use

Tablets and capsules are taken, depending on the indications, 3-4 rubles / day. A single dose of Levomycetin in tablets / capsules for an adult is 1-2 tab. 250 mg. The highest dose is 4 tab. 500 mg per day.

In particularly severe cases (eg. peritonitis or typhoid fever ) the dose may be increased to 3 or 4 g/day.

Duration of application - no more than 10 days.

Levomycetin is often used for diarrhea that occurs when food is poisoned, as well as in cases where intestinal upset is the result of a bacterial infection.

Levomycetin tablets for diarrhea are taken before meals, one every 4-6 hours. The highest dose is 4 g / day. If after taking the first 500 mg tablet the disorder has stopped, the second one should no longer be taken.

How to take Levomycetin for cystitis

Despite the fact that the use of Levomycetin drops in infants allows you to dry the mucous membrane and reduce the flow of snot, it has been proven that topical application antibiotics often fails to effectively deal with bacterial infection .

If we talk about the treatment scheme according to the principle “ off-label prescription” (not for its intended purpose), then Levomycetin is instilled into the ear 3-4 drops, into the nose - 1-2 drops. Treatment lasts from 5 to 10 days. The frequency of procedures is 1-2 per day.

Before you make the drug in the nose, you must first drip a vasoconstrictor. Before applying to the ear, the external auditory canal should be cleaned of pus.

Application in veterinary medicine

In veterinary practice, Levomycetin is used for colibacillosis , salmonellosis , leptospirosis , dyspepsia , colienteritis , coccidosis And pullorose chickens, infectious and mycoplasmosis birds, urinary tract infections And bronchopneumonia .

The dose for farm animals, as well as for cats and dogs, is selected depending on the weight and severity of the disease.

How to give chickens the drug? To avoid mass death of chickens from intestinal infection they are given 1 tablet of Levomycetin 2 times a day with food for 3-5 days. This dosage is calculated for 15-20 chicks.

Analogues

Coincidence in the ATX code of the 4th level:

drugs with the same active substance: Levomycetin Aktitab , Levomycetin sodium succinate .

Analogues according to the mechanism of action:

• for Levomycetin tablets - ;bacterial keratitis , purulent ulcers of the cornea of ​​the eye , blepharitis, conjunctivitis , chlamydial And gonorrheal diseases in adults, and blennorey in newborn babies.

  Albucid , unlike Levomycetin, causes severe eye irritation.

  The use of Levomycetin for children

  The use of Levomycetin tablets in pediatrics

  Tableted forms of the drug in pediatrics are used under constant monitoring of serum concentrations. chloramphenicol . Depending on age, the dose of Levomycetin tablets for children ranges from 25 to 100 mg / kg / day.

  For newborn infants under the age of 2 weeks (including premature infants), the formula for calculating the daily dose is as follows: 6.25 mg / kg for each dose with a frequency of applications up to 4 r. / Day.

  For infants older than 14 days, 12.5 mg / kg is prescribed for 1 dose every 6 hours or 25 mg / kg every 12 hours.

  For severe infections (eg. ) the dose is increased to 75-100 mg / kg / day.

  How to take Levomycetin for diarrhea?

  The drug is a fairly serious remedy and therefore should be prescribed by a doctor. However, it is often given to children when needed to relieve an intestinal disorder.

  As a rule, the dose for children 3-8 years old is from 375 to 500 mg / day. (125 mg per 1 dose), for children 8-16 years old - 750-1000 mg (250 mg per 1 dose).

  With diarrhea, a single use of the drug is allowed. If the child's condition does not improve, and the symptoms persist even 4-5 hours after taking the pill, you should consult a therapist.

  Eye drops Levomycetin for children

  Eye drops for newborns (in the first 4 weeks after birth) are used only for health reasons.

  Levomycetin eye drops for infants are also used with caution. Usually, antibiotic instill 1 drop into conjunctival sac each eye every 6-8 hours.

  At barley eye drops are not recommended for children under 10 years of age.

  The use of external therapy in children

  The solution is not intended for the treatment of children under 1 year old, liniment is not used to treat premature and newborn babies.

  Levomycetin and alcohol

  Alcohol and chloramphenicol incompatible. With simultaneous use with ethanol, there is a high risk of developing a disulfiram-like effect, which manifests itself , hyperemia skin, nausea and vomiting, reflex cough, convulsions.

  Levomycetin during pregnancy

  Levomycetin for external and systemic use is contraindicated in pregnancy. If the drug is prescribed to a nursing woman, the child must be transferred to artificial feeding for the duration of treatment.

  If indicated, eye drops can be used in pregnant women and during lactation, however, provided that the dosages recommended by the instructions are not exceeded.

Instruction

for medical use

medicinal product

Levomycetin

Tradename

Levomycetin

International non-proprietary name

Chloramphenicol

Dosage form

Eye drops 0.5% 8 ml, 10 ml

Composition

1 ml of solution contains

active substance- chloramphenicol 5 mg,

Excipients: boric acid, polyvinylpyrrolidone, water for injection

Description

Yellowish clear or slightly opalescent liquid

Pharmacotherapeutic group

Drugs for the treatment of eye diseases. Antimicrobials. Antibiotics. Chloramphenicol

ATX code S01AA01

pharmachologic effect

Pharmacokinetics

When instilled into the eyes, a therapeutic concentration of chloramphenicol is created in the vitreous body, cornea, iris, aqueous humor of the eye. Levomycetin does not penetrate into the lens of the eye. Due to the presence of polyvinylpyrrolidone, the drug has a high viscosity and good adhesive properties in relation to the anterior surface of the eye, the duration of contact of the solution with the cornea increases, and the therapeutic effect of the drops is extended. A uniform, long-lasting precorneal tear film is formed, which is not washed off for a long time when blinking and does not cause a decrease in visual acuity.

Pharmacodynamics

Levomycetin is a broad-spectrum antibiotic, effective against many gram-positive and gram-negative bacteria. The mechanism of antimicrobial action is associated with inhibition of RNA synthesis at the level of 50-S ribosome substance and inhibition of protein synthesis.

Effective against strains of bacteria resistant to penicillin, tetracyclines, sulfonamides. Active against Escherchia Coli, Haemophilus influenzae, Klebsiella pneumoniae, some Enterobacter and Neisseria species, Staphylococcus aureus, Streptococus spp. Not effective against Pseudomonas aeruginosa, Serratia marcescens.

It has a bacteriostatic effect. Habituation of microorganisms to chloramphenicol develops slowly.

Indications for use

Conjunctivitis

Keratitis

Keratoconjunctivitis

Corneal ulceration

Blepharitis

Blepharoconjunctivitis

Dosage and administration

1-2 drops 3-4 times a day for 5-7 days. Then you need a break for 3-5 days.

Side effects

Possible local allergic reactions

With prolonged use - a decrease in visual acuity

Neuritis of the optic and peripheral nerves

Contraindications

Increased individual sensitivity to the drug

Inhibition of bone marrow hematopoiesis

Skin diseases (psoriasis, eczema, fungal diseases)

Pregnancy and lactation

Acute intermittent porphyria

Glucose-6-phosphate dehydrogenase deficiency

Liver/renal failure

Children's age up to 1 year

drug interaction

To prevent an increase in the inhibitory effect on hematopoiesis, it is not recommended to use it together with sulfanilamide drugs, cytostatics.

special instructions

Unreasonable use of the drug is not allowed, especially in childhood.

Do not use for viral and fungal eye infections.

It is used with caution in patients receiving cytostatics and radiation therapy.

It is necessary to ensure that the tip of the dropper bottle does not come into contact with the surface of the mucous membrane of the eye. After instillation, the dropper bottle is closed with a cap.

With prolonged use, systematic monitoring of peripheral blood is necessary, since chloramphenicol can cause aplastic anemia, agranulocytosis.

Features of the effect of the drug on the ability to drive vehicle or potential dangerous mechanisms

The drug does not affect the ability to drive vehicles and work with other dangerous mechanisms.

In order to treat bacterial inflammatory processes in the organs of vision, antimicrobial eye drops Levomycetin are used. One of the advantages of using the drug is that a person does not get used to it too quickly, so drops are allowed to be used even for the treatment of infants.

Composition and form of release

Levomitsetin 0.25% eye drops are produced in sterile 10 ml vials. Also on the shelves in pharmacies you can see a gel or eye ointment with chloramphenicol. The active ingredient in the preparation is chloramphenicol. Auxiliary components - boric acid and purified water.

To date, many pharmaceutical factories and firms are engaged in the production of drugs with Levomycetin. Basically, the name of the drug consists of the active substance and the name of the company or manufacturer (for example, Levomycetin-AKOS, Levomycetin-DIA, etc.). Imported drugs containing levomycetin may be called differently.

pharmachologic effect

The instructions for use say that Levomycetin eye drops help to overcome infections of bacterial origin that affect the eyeball. The drug is often prescribed when weaker drugs and antibiotics of the penicillin series are powerless.

The drug, once on the mucous membrane, inhibits the production of protein in pathogens. The resistance of these microorganisms to the drug is very low, so a long course of treatment will be required, during which there is no need to replace the medication. The drug is actively introduced into the sclera and vitreous body and, without touching the lens, begins to be actively absorbed into the systemic circulation. The effect of the drug begins already half an hour after the procedure.

Mode of application

Based on the instructions for the use of Levomycetin, instillation should be carried out three times a day, one drop in each eye. The duration of therapy is on average a week, but only a doctor can determine exactly how many days it will take.

Before dripping the drug into the eyes, wash your hands, then shake the contents of the vial thoroughly. A huge number of people do not understand whether the medicine is considered an antibiotic or not. Levomycetin is antibacterial drug therefore, it can be used in the treatment of eye diseases only after receiving a prescription from a doctor.

For instillation, you need to pull the lower eyelid down, forming a conjunctival sac, and look up. The bottle with the drug is brought to the eye so as not to touch it with the tip of the eyeball (this can injure the organ). After hitting the medicine, you need to blink several times, and then repeat the procedure for the second eye.

Correct instillation of eye drops is very important for effective treatment.

When using Levomycetin ointment, it is laid behind the lower eyelid five times a day. The tube with the drug is pre-heated in the hands. When the ointment is already under the eyelid, it is necessary to make circular movements with the hand so that the product evenly spreads.

Indications for use

The use of eye drops with chloramphenicol is recommended for such ophthalmic diseases of an infectious nature:

• barley;
• conjunctivitis;
• blepharitis;
• keratitis.

Adverse reactions and contraindications

Often, if the use of Levomycetin drops was carried out correctly, side effects not visible. However, with the parallel use of the drug with other drugs that depress hematopoiesis, the patient may experience:

• active tearing;
• itching in the eyes and eyelids;
• redness around the conjunctiva;
• secondary fungal infection.

When such adverse reactions specialists replace the drug with an analog one.

Contraindications to therapy:

• hypersensitivity to the components of the drug;
• kidney and liver failure;
• violation of hematopoietic function;
• the period of bearing a baby;
• breast-feeding;
• eczema.

Use in children

Levomycetin is contraindicated in children who are under two years old. The drug is prescribed to newborns from the age of four months, however, therapy is carried out under the full supervision of a specialist. When using a drug to treat a child, you need to be aware of the possible occurrence of adverse reactions in the form of nausea, vomiting, and gastrointestinal upset.

Terms and conditions of storage

In a pharmacy, the drug can be stored for no more than two years, after which the remains are disposed of. If the bottle has been opened, it must be used within a month. Store the drug in a dark place, observing the temperature regime from eight to fifteen degrees.

Analogues

In drops with levomycetin, there are analogue preparations that have differences in composition, but have a similar therapeutic effect:

• Sulfacyl sodium. The drug is prescribed for the treatment of conjunctivitis, keratitis, ulcers in the cornea. The downside of the drug is that pathogens develop resistance to it, so the specialist has to replace the drug;
• Albucid. The medicine helps to eliminate inflammation of the eyeball, lesions of the anterior segment of the eyes. Many recommend the use of the drug in order to prevent infectious diseases in the organs of vision;
• Phloxal. This is a broad-spectrum antibacterial drug that is used to treat infectious and inflammatory diseases of the anterior part of the organs of vision, bacterial infections resulting from eye injury or surgery;
• Tobrex. A drug that has repeatedly shown its effectiveness in the fight against inflammatory and infectious eye diseases. The medicine has a minimum number of possible side effects and is approved for use by both adults and children.

Drugs with a similar effect

Price

The popularity of Levomycetin drops is due not only to their effectiveness, but also to their low cost. On the territory of Russia, the price of a bottle of drops is from forty to fifty rubles. In Ukraine, the drug costs from seven to twelve hryvnia.

Levomycetin is an effective and inexpensive eye drop based on chloramphenicol. Ophthalmologists recommend the use of Levomycetin eye drops in most cases of infectious lesions of the cornea and deeper structures of the eye.

At the heart of these budget drops (the price for a bottle of 10 ml is in the range of 19-27 rubles) is the chloramphenicol compound. In 1 ml of eye drops it is 2.5 mg. Boric acid is also present here in small quantities. Chloramphenicol is antimicrobial drug broad spectrum (antibiotic). In addition to these two components, the composition also includes purified water, some other excipients.

Drops are sold in a convenient plastic container - dropper bottles of 10 ml.

The mechanism of action of Levomycetin

Levomycetin is indicated in many cases of infection of the eye and its components. It is effective against infection with gram-positive and gram-negative strains. Including in many of those cases when bacteria are insensitive to penicillins, streptomycins and sulfonamides.

The action of chloramphenicol is due to the inhibitory effect on protein production in the DNA of microorganisms. As a result, they are stabilized. important points in the use of Levomycetin there will also be the fact that it has a low level of resistance (adaptability) of microorganisms, which allows it to be used for a long time with high efficiency results.

Chlorampinecol penetrates the iris, sclera, eye chambers and vitreous body, but does not penetrate the lens. In addition, it is absorbed into the systemic circulation.

The maximum efficiency comes in 30 min. after the instillation procedure. The highest concentration is recorded in the anterior chamber of the eye.

Indications for the use of eye drops Levomycetin

Levomycetin drops are used for infectious diseases eyes caused by microorganisms sensitive to this drug. So in figures 1-3 the main types of eye diseases are presented, in which this medicine should be used. Among those will be:

• conjunctivitis (inflammation of the inner layer of the eyelids - conjunctiva) of infectious origin;
• keratitis (inflammation of the cornea);
• blepharitis (inflammation of the eyelids or barley);
• keratoconjunctivitis.

Eye keratitis

Ophthalmologists also attribute Levomycetin in cases where other non-steroidal anti-inflammatory ophthalmic drugs are ineffective. It quickly relieves purulent inflammation, clears the eyes. This drug is used to treat eye infections in children.

Blepharitis eyes

When Levomycetin can harm

However, Levomycitin eye drops are an NSAID-based medicine. And they, like other drugs, have a number of contraindications for use, they can have side effects.

So, among the side effects will be:

• burning sensation in the eyes;
• redness of the cornea and eyelids;
• hyperlacrimation.

In addition, children may experience:

• nausea and vomiting;
• diarrhea;
• drop in the level of hemoglobin in the blood.

Conjunctivitis of the eye

With long courses of treatment, hematopoietic disorders are very rarely observed: leukopenia, anemia or thrombopenia.

Careful application of eye drops Levomycetin

Due to possible side effects, in some cases, chloramphenicol eye drops should be used after consultation with an ophthalmologist and in strict accordance with the instructions. They are used with caution in the following cases:

• for children over 2 years old. Here, treatment with Levomycetin should take place after consultation with an ophthalmologist, pediatrician and with strict adherence to the instructions. In some cases pediatric ophthalmologist can prescribe the drug to a child from 4 months, but here the expected useful action should exceed possible side effects;
• chlorampinecol penetrates into the systemic circulation, so it should be used carefully by nursing mothers, it is better to stop feeding. It is necessary to consult and supervise a doctor;
• with radiation therapy or a history of cytostatic treatment, treatment with Levomycitin should be carried out very carefully. Perhaps the development of bone marrow hypoplasia;
• if the work involves a strain of attention or vision. If you need to work with complex mechanisms or drive a car. due to decreased visual acuity.

Contraindications to the use of eye drops Levomycetin

Among the contraindications for use, first of all, allergic reactions to the constituent drugs should be noted.

Do not use chloramphenicol eye drops also in the following cases:

• in acute hepatic or kidney failure or their chronic forms;
• if there is a history of porphyria;
• with diseases of eczema and fungal diseases of the skin, as well as psoriasis;
• during pregnancy;
• children under the age of 4 months;
• in violation of hematopoiesis. Here anemia, leukopenia can intensify.

Interaction of eye drops Levomycetin with other antibiotics

Levomycetin has the ability to reduce the effectiveness of other antibiotics. In this case, the beneficial effect of the drug itself is also reduced. When using these eye drops at the same time as one of the following NSAIDs:

• erythromycins;
• lincomycin;
• phenobarbitals;
• phenytoin;
• penicillin preparations;
• cephalosporins

the action of Levomycetin, as well as another drug, will decrease.

Interaction of Levomycitin with other drugs

With simultaneous use with radiation therapy or drugs that depress hematopoiesis, there is an increase in side effects. As a rule, for violations of hematopoiesis, radiation therapy and treatment with hemostatics, Levomycetin drops are not used.

How and when is it better to drip Levomycetin eye drops

Usually this drug is prescribed 1 drop into the conjunctival sac every 4 hours. In the most difficult cases, the instruction provides for a reduction in the interval to 1 hour.

If there are lenses, they should be removed before instillation and put on no earlier than 0.5 hours after the procedure.

The vial is an individual package and should only be used for one patient.

When digging in, it is very important to adhere to simple rules hygiene:

• wash your hands before the procedure;
• do not touch the tip of the dropper to the eye and other surfaces;
• carry out the procedure in a clean room;
• keep the vial tightly closed.

The dose must be discussed with the optometrist and before using the drug, study the instructions.

An overdose is manifested by a decrease in vision. In these cases, the medicine from the eye should be washed with plenty of clean water.

Cases of poisoning with chloramphenicol during the treatment of eye diseases have not been recorded.

Children should not use drops without consulting a doctor. In addition, before using the medicine, be sure to carefully study the instructions.

Analogues of eye drops Levomycetin

Among the analogues of this drug can be called a number of eye drops: Floxar, Normax, Tsipromed, Sulfacyl sodium and Albucid, as well as Tobrex. All of them in their composition have antibiotics, a wide spectrum of action. If we compare them with Levomycetin eye drops, then they will have:

• narrower spectrum of action;
• a higher degree of resistance (microbes get used to them faster, and this reduces their effectiveness);
• and also have a much higher price compared to Levomycetin.

Levomycetin eye drops are indicated for use both for adults and for children from 4 months, they have an extensive antimicrobial effect and a relatively low price. This makes them indispensable in every home first aid kit.